Patients harboring the Broad11934905A allele were found to have a higher pathologic stage (pT3-4) and showed a trend toward earlier biochemical recurrence, compared to individuals with the wild type allele.
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As regards the prognostic significance of the JAK2 haplotype GGCC_46/1 in AML cases, it was demonstrated that cases with a normal karyotype bearing the haplotype GGCC_46/1 showed a trend towards myelomonocytic proliferation and shorter disease-free survival and overall survival compared to GGCC_46/1 non carriers; on the other hand, the haplotype GGCC_46/1 had no impact on prognosis in the subgroup of AML with an abnormal karyotype [ 13 , 25 ].
However, experimental groups of some donors showed a trend of higher ALP activity/total protein content than the corresponding positive control. 2.2.
1c ), and although the gene expression of catalase, superoxide dismutase 1 showed a trend to decrease in the presence of taurine, it was not significant (Fig. 1d ).
In addition, adjusted Cox proportional-hazards regression analysis showed a trend towards higher risk of RRT with lower calcium levels at baseline (Supplementary Table S11 ).
Stepping Parameters All of the stepping parameters showed a trend of decline by frailty progression ( Table 2 ).
Data from the primary prevention ICD patients with ischaemic heart disease enrolled in the Danish ICD registry also showed a trend towards higher mortality in men. 23 In patients with non-ischaemic cardiomyopathy, however, there was no difference in mortality. 16 In contrast to our results, the French DAI-PP registry only showed a lower mortality in women receiving a CRT-D (HR 0.68; P = 0.034) but no significant lower mortality of women in the overall primary prevention ICD cohort (HR 0.87; P = 0.32). 17 This difference to our findings can in part be explained by the fact that 61% of women in the French study but only 51% in our study received a CRT-D.
Vision-related quality of life showed a trend toward improvement in the DHA supplementation group at 45 and 90 days as compared with baseline, and a trend toward worsening in the control group (between-group differences P =0.037) ( Figure 5 ).
The LPSp-treated mice showed a trend towards an increase in phagocytosis compared with the HFD-fed mice.
Cravings to smoke did not differ significantly across Phases A1, B and A2, but graphical analysis showed a trend for decreasing cravings.
Ptges3 and Cbr1 were found to be significantly up-regulated in Cyp2j4 −/− macrophages ( Figure 5 D) whereas Cyp2j4 −/− SVF showed a trend for up-regulation of Ptgis after CAF ( Figure 5 E).
The general LI of Ki67 showed a trend of gradually increasing from NAG stage to GC stage groups, except slightly decreased in CAG groups.
Subgroup analyses of ACR response rate, EULAR response, and proportion of patients with low disease activity and remission (according to the DAS28, SDAI, and CDAI) showed a trend toward decreased efficacy in antidrug antibody–positive patients (n = 84) compared with antidrug antibody–negative patients (n = 423) in all treatment groups (see Supplementary Table 1 , http://onlinelibrary.wiley.com/doi/10.1002/art.40444/abstract ).
The EORTC 26981/22981-NCIC CE3 study excluded patients over 70 [ 1 , 2 ], and although a subgroup analysis showed a trend toward benefit in patients over 60 years old, the degree of benefit diminished with increasing age [ 19 ].
Looking at longer term effects, all methods showed a trend with the treatment effect becoming more negative through time, with truncated IPW estimating the largest difference in ppFEV 1 between those taking and not taking treatment of −8.81% (95% CI, −10.50 to −7.12, P < .001) and HA‐MSM the smallest effect of −1.52% (95% CI, −3.30 to 0.27, P = .097).
The ITT conducted at 16th week on HFD revealed that insulin sensitivity of the NEU1-GFP AV-infected group showed a trend for reduction as compared with the GFP AV-infected group ( Figure 6 B).
In addition, Lac/Cr in tumor showed a trend towards association with OS-1, with higher Lac values predicting poorer outcome (AUC = 0.78, 95% CI: 0.49 to 1.00).
A fixed effects model showed a trend in improving family functioning at post-intervention in intervention group couples.
Although rMRP14-injected mice showed a trend towards an increase in inflammatory molecules compared with PBS-injected controls during Pb-infection, we found no significant differences among the two groups.
Data We also wanted to evaluate whether PTB generally showed a trend toward moderate or high within-herd prevalence in dairy herds.
Whereas, the rest of the 6 in the HI group showed a trend of lesser masking release than the NM group.
Anti-CD37 antibody also showed a trend toward the inhibition of SGC formation in Cl and NCl monocytes.
In the results of IOA, the values varied through most cases and showed a trend of gradual increase with the amount of error, demonstrating strong distinguishability of QA results.
Patients with pre-treatment HER2-positive tumors showed a trend towards better overall survival, but no association between HER2 discordance and survival was seen.
Analysis of data from 1,926 NSCLC patients showed a trend of high FLAP expression correlating with a lower overall probability of survival, but this was not statistically significant ( P = 0.15, HR = 1.1) (Figure 1A ). 1,244 of these patients had an NSCLC subtype associated with their data.