“showed a trend”

Signs of life ( p = 0.03) and witnessed cardiac arrest ( p = 0.04) showed a trend towards improved neurological outcomes, however both failed to reach the Bonferroni-corrected p-value threshold.

Further analysis of the individual lesions showed a trend towards a higher level of tumor heterogeneity, as measured by K app , in the pseudoprogressive lesions throughout the first 12 weeks of treatment (baseline: 0.84; 3 weeks: 0.64; 12 weeks: 0.76) compared with the responding lesions (baseline: 0.59; 3 weeks: 0.54; 12 weeks: 0.56); although this did not reach statistical significance, it may reflect underlying immune cell infiltration or cell death over the course of treatment.

In our current study we found that microstate D showed a trend toward a decrease in CHMP2B -FTD as compared to controls.

The IgG responses to the seven vaccine serotypes showed a trend consistent with the OPA responses (Supplementary Figure 2).

27 Despite the proven benefits of statins, the data from the SPARCL (Stroke Prevention by Aggressive Reduction of Cholesterol Levels) trial showed a trend toward an increased rate of ICH with statin therapy. 28 However, a post hoc analysis revealed that the highest risk was linked to previous hemorrhagic stroke, and there was no relationship between ICH and low‐density lipoprotein cholesterol levels. 29 , 30 In the present study, we found that statin therapy was associated with a lower risk of ICH.

In Cluster II, the DEGs showed a trend of increased expression and were identified to be related to the deposition and formation of SCW, biosynthesis of secondary metabolites, various transport pathways, and signaling pathways, and as those dramatically enriching lignin biosynthesis, transport of nitrogen compounds, and transmembrane transport of amino acids, like the PAL gene (PH02Gene27016) and LAC gene (PH02Gene03534).

In a phase II clinical study focusing on head and neck cancer that enrolled seven NPC patients, sorafenib was well tolerated and showed a trend of longer time to progression, but this was not statistically significant. 298 The combination of sorafenib, cisplatin, and 5‐fluorouracil was shown to be tolerable in 54 recurrent/metastatic NPC patients, but the contribution of sorafenib to the chemotherapy was not clear. 299 In a phase II trial of pazopanib in 33 patients with recurrent/metastatic NPC, the partial response rate was 6.1%, with the clinical benefit rate of 54.5%. 300 Sunitinib was assessed for its efficacy and safety in 14 pretreated recurrent/metastatic NPC patients.

High SREBP1c also showed a trend of association with poor survival, although not statistically significant (Figure 4C ).

Indeed, our analyses showed a trend of T cells to move towards tumor cells following CXCL12 inhibition in all patients that were classified as tissue responders ( figure 6E ).

Inflammatory cytokines IL6 and TNFα mRNA levels showed a trend for increased expression at early time-points to end with a significant decrease at 48 h after surgery.

In order to validate the presence of IFN-γ cytokine that could induce this pattern of gene expression by the tumor cells, we tested whole tumor lysates with an IFN-γ ELISA (data not shown); this showed a trend for more IFN-γ in tumor-bearing mice compared with healthy brains, presumably derived from infiltrating T cells and NK cells.

Combined DB extract and THP treatment showed a trend suggesting that cardiotoxicity could be strengthened by DB supplementation.

For example, previous experimental results of endothelial cell transcriptome analysis of sepsis revealed that AL132709.5 lncRNA was significantly upregulated, while CTC-45916.1 lncRNA, 45916.1 lncRNA, and lncRNA XLOC_007697 showed a trend of downregulation ( 26 ).

The younger adolescent group showed a trend toward more perseverative errors in the Environmental Noise condition ( M = 5.52, SD = 4.72) compared to those in the White Noise condition ( M = 3.08, SD = 2.25), p = 0.064; however, there was no difference between the noise conditions for the older adolescents ( M enviro = 4.26, SD enviro = 3.99 and M white = 5.19, SD white = 4.73), p = 0.49.

They found that treatment with anti–Tim-3 alone had little or no effect and treatment with anti–PD-L1 alone showed a trend toward delayed tumor growth, but this varied between experiments and did not reach statistical significance.

The pump prime group showed a trend toward less inotropic support, shorter LOS, and less oxidative stress, but the study was, again, not powered for outcome measures.

Knowledge of the number of contraception methods " Known modern methods" showed a trend of dose-response relationship supporting a stronger causal relationship between knowledge of the number of contraception methods and utilization of contraception.

The study completed by Caironi et al and showed that there was no difference in mortality for patients with septic shock between patients receiving albumin versus normal saline, but a meta-analysis by Xu et al showed a trend toward lower 90-day mortality in severe sepsis patients treated with albumin versus crystalloid therapy [ 10 , 11 ].

Simultaneously, Col 1 and Col 3 protein expression showed a trend similar to that of CTGF (Figures 7(c) and 7(d) ).

2 showed a trend similar to that in Fig. 1 .

17 , 20 , 40 , 41 Multivariate model in our study showed a trend toward significant decrease of dysrhythmia with greater CD4 counts which was close to previous reports. 42 This may underline the role of optimal treatment for reducing dysrhythmias particularly prolonged QT.

Evaluation of patients who did not do well showed a trend of falling PA pressures with raising CVP and falling urine output.

Second, the graphitization degree of deadman coke was extremely high and showed a trend of first increasing and then decreasing.

With the extension of smoking time, the L* values of smoked chicken thighs generally showed a trend of decreasing (0–12 min) and then stabilizing (12–16 min).

The GTV of all patients had different degrees of change from C 0 to the last SCTS and showed a trend of gradual shrinkage, in which the largest volume shrinkage rate was 78.1% (gefitinib, thick red solid line) and the smallest was 18.8% (icotinib, thick black solid line) ( Figure 1 ).