In a large Canadian cohort of 132,256 births, maternal exposure to NO was associated with increased risk of development of autism spectrum disorders in children (OR 1.07, 95% CI 1.01–1.13 per IQR increase), whereas associations were less pronounced (or only showed a trend) for PM2.5 (OR 1.04, 95% CI 0.98–1.10) and NO 2 (OR 1.06, 95% CI 0.99–1.12) [ 97 ].
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In the literature
The effect of Si306 was similar in U87-TxR cells, while pro-Si306 showed a trend of decreasing the pAKT/AKT relative expression.
In another study, the single nucleotide polymorphism rs35829419 revealed a significant association with increased IL-1β levels, but showed a trend with lower levels of plasma CRP, suggesting a relevant complexity in the impact of these SNPs [ 64 ].
Moreover, placebo treatment showed a trend towards heart rate increase reaching comparable values of the Red Bull group until the end of hypoxia ( Figure 1 ).
A nonparametric test for trend across ordered groups, an extension of the Wilcoxon rank-sum test, was used to explore the relationship between tertiles of dairy consumption and change in clinical outcomes followed by step-wise univariate and multivariable linear regression models adjusted for candidate covariates to investigate the association between average dairy consumption and selected outcomes that showed a trend in the initial analysis (changes in HDL-C, and VLDL-C).
With regard to MS prevalence and its individual components ( Table 3 ), the age-, sex-, baseline status- and CPAP use-adjusted relative risk of decreased HDLC was significantly lower in both intervention arms compared to the SCG, the MLG additionally presented a lower relative risk of increased WC, increased TG and hypertension compared to the SCG, while the MDG only showed a trend for a lower risk of increased TG and hypertension compared to the SCG.
Kaplan-Meier survival analysis showed a trend of shorter progression time by interim imaging reassessment for patients with at least three CTCs (median TTP 79 days) at baseline compared to 0–2 CTC (median TTP 94 days) ( p = 0.090) ( Figure S2A ). 2.2.3.
Elderly HNSCC patients with reduced kidney function who were treated with radiotherapy alone showed a trend towards lower OS, although statistical significance was not reached ( p = 0.112).
Moreover, three of them showed a trend of upregulation during disease progression from healthy controls to primary and metastatic melanoma cases. 2.
LPCs showed a trend towards reduced levels in samples from CCA, which reached statistical significance in those from PDAC patients.
Subtype was significantly associated with the presence of distant metastasis at diagnosis and showed a trend towards significant association with lymphovascular invasion (LVI) at diagnosis, with a higher proportion of cases with LVI and distant metastasis for subtype A compared with B.
It should be noted, however, that at day 3 the CK levels showed a trend to be greater in the placebo group (∆456 (IQR: 209–885) U/L) compared to the protein group (∆283 (IQR: 182–662) U/L).
In all cases, the proportion of cells expressing CD62L showed a trend to increase with age (~64% rise, day 21 vs. day 14), and the percentage of cells expressing CD103 tended to decrease with age (~63% of reduction, day 21 vs. day 14), without significant differences observed among the groups. 4.
Thus, according to the results of basic postural tests in a bipedal stance with EO and EC, COP fluctuations did not correlate with performance level in Figure Skating and showed a trend to increase in high-class athletes. 4.
At the same time point, in MV plants (condition corresponding to the challenge state), ABA level showed a trend towards a decrease in favor of SA accumulation, possibly due to the antagonistic role of ABA and SA in defense responses [ 46 ].
Group A showed a trend toward a higher clinical pregnancy rate than Group B or Group C, but there was no statistical significance, whatever by IVF or by natural.
For the above two inflammatory factors in the serum, the ELISAs showed a trend similar to that in the cartilage tissue.
Relative to the Peceol ® suspension, sLBF showed a trend towards a quicker absorption and shorter MRT and t max .
Although not significant, CV death showed a trend toward a higher rate in the PCI group.
MET FISH analysis showed no benefit of onartuzumab, while EGFR -mutated patients showed a trend toward short OS when treated with onartuzumab (HR: 4.68; 95% CI: 0.97–22.63).
didyma showed a trend not very different from its spontaneous emission because it conserved the predominance of the same class of compounds: OM (84.5%).
On the other hand, the electronic density of Au 60 S n (SR) 36 ( n = 0–12) showed a trend that from the metal NC Au 60 (SR) 36 to the gold-sulfide QD Au 60 S 12 (SR) 36 , the LUMO density distribution gradually changed from the local distribution on the Au core to the diffusion distribution on the Au–S(μ 4 ) skeleton.
Of note, the after-image duration showed a trend towards elevation (in comparison to the interictal phase) starting 2 days before the headache and lasted up to 1 day after the headache stopped ( 22 ).
In our study, the mildew resistance locus 12 gene ( MLO12 ) had one associated transcript with complete downregulation in all treatments ( Figure 5C ), and a second transcript slightly upregulated at 7 dai in both genotypes ( Supplementary Figure S3A ), while a transcript matching MLO2 showed a trend similar to the second MLO12 transcript.
In addition to this, the study found that, among the tested onset times, the earlier ones showed a trend for bigger reductions of the activation of the soleus muscle during stance, while the later ones led to a bigger reduction in the metabolic cost of walking in the assisted walking trials as compared to the unassisted condition.