“showed a trend”

A more detailed assessment of the HRT formulations evidences a modest increased risk of PD in users of estrogen replacement therapy (ERT) in 2 cohort studies ( Simon et al., 2009 ; Liu et al., 2014 ) in contrast to 6 case–control studies ( Benedetti et al., 2001 ; Baldereschi et al., 2003 ; Currie et al., 2004 ; Ragonese et al., 2004 ; Gatto et al., 2014 ; Lundin et al., 2014 ) that showed a trend for a protective or no effect of ERT.

It has not been possible to identify a single treatment associated with statistically higher QoL; however, parents showed a trend toward the belief that their children with SMA have a greater QoL with current treatments compared to supportive care [ 78 ].

Moreover, the divergent regions include trn K- trn Q, trn S- trn G, trn C- pet N, trn E- trn T, pet G- trn W- trn P, and trn L- rpl 32, where previous reports found that these divergent regions were mostly present in the SSC and LSC regions and showed a trend toward more rapid evolution [ 22 , 57 , 58 , 59 ].

( 23 ) suggested a trend toward reduced rates of 1-year death with TAVI in RCTs in low-risk populations, whereas observational studies with PSM in the same meta-analysis showed a trend toward increased rates of death with TAVI.

The mean overall parkour error showed a trend to increase with decreasing TNO and the mean overall parkour time showed a trend to decrease with decreasing TNO.

The mixture of Zr(i-PrO) 4 and G-CGS/ZnS and R-CIS/ZnS QDs showed a trend of photo-stability as a function of UV irradiation similar to that of pristine G-CGS/ZnS and R-CIS/ZnS QDs.

In the microarray Cohort-A, B cells and mast cells were significantly higher, the T cell and TIS signatures showed a trend for higher expression.

Correlation analysis of activity grade with serum TSP2 levels based on fibrosis stage showed a trend towards correlation in F2 and F3–4 patients, although this difference did not reach statistical significance (P = 0.2182 and P = 0.0624, respectively) (Fig. 2 d).

In addition, an exploratory comparison between the current study data and historical data showed a trend toward earlier negative blood viral load in patients treated with viral adsorption therapy.

In contrast, plasma glucagon levels only showed a trend of decrease in the whole gut gcg knockout mice and no change in distal gut gcg knockout mice compared with wild type mice, suggesting glucagon production is mainly produced from the pancreatic α-cell.

The transcriptional levels of these tested genes through qRT-PCR analysis showed a trend similar to that of the RNA-Seq data ( Supplementary Figure S2 ), indicating the high reliability of the RNA-Seq data.

Most of the risky genes showed a trend of positive correlation with macrophage infiltration and negative correlation with B cells.

Moreover, the total citations showed a trend similar to that of annual publications.

Except for fluoroquinolones, the DOT per 1,000 PD for carbapenems, piperacillin-tazobactam, and cefepime showed a trend toward a significant increase (Supplementary Fig. 1 ).

The same results were observed for the CEA values that showed a trend of reduction although not statistically significant.

T cell subsets, NK cells and natural killer T cells (NKT) showed a trend for reduction, although not significant (CD3 + CD4 + T cells: 0.39 ± 0.05 vs. 1.67 ± 0.15 * 10 2 cells/μl; CD3 + CD8 + T cells: 0.16 ± 0.03 vs. 1.03 ± 0.12 * 10 2 cells/μl; NK cells: 0.15 ± 0.03 vs. 1.00 ± 0.25 * 10 2 cells/μl; NKT cells: 0.02 ± 0.01 vs. 0.11 ± 0.03 * 10 2 cells/μl; for all cell subsets p > 0.05).

As depicted in Figure 5 , the economic linkage of the GBA from 2010 to 2020 was rising fast, and the linkage of Guangzhou-Foshan occupying the core position showed a trend of extending from the central city to the peripheral cities.

Survival curve analyses showed that a significantly higher number of H-GSH rats reached higher breakpoints ( Figure 3—figure supplement 1h ) and this group also showed a trend toward nosepoking over a longer period of time ( Figure 3—figure supplement 1i ).

Patients with Non-painful Diabetic Neuropathy (NPDPN Q+SOC) showed a trend toward an improvement of the warm threshold, but it was not statistically significant.

Correlation of DTI metrics and cognitive output Low diffusivities showed a trend towards higher cognitive scores in many ROIs but in most cases, it did not reach statistical significance after correction of the p -value for multiple comparisons.

The RMSD of the compound relative to 3-C like protease maintained an increasing trend in the first 25 ns or so, and showed a trend of decreasing and then increasing to the RMSD value at 25 ns from 25 to 40 ns, and basically maintained equilibrium with less fluctuation in the last 10 ns.

Both EXTEM and INTEM CT showed a trend towards longer clotting time indicating reduced amounts of clotting factors.

Since in TASTPM we detected a significant sham effect and SNI ipsilateral thresholds showed a trend to be higher than WT, we performed an area under the curve (AUC) analysis.

Mice subsequently treated with Abatacept and IgG-(IL-2) 2 showed a trend towards retention of more functional beta cell mass as judged by glucose tolerance tests (Supplementary Fig. 8 ).

The third study failed to demonstrate antidepressant efficacy of pioglitazone over placebo and in fact showed a trend favoring placebo.