showed a trendP = 0.054
This analysis indicated that the microbicide alone over the entire course of parts 1 and 2 showed a trend toward protection (OR, 0.26 [0.06:1.02]; P = 0.054; Table 6 ), whereas the microbicide and vaccine combined provided significant protection, with a 91% reduction in the per-exposure probability of infection ( P = 0.004; Table 6 ).