Barely Significant
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trending toward significance

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In the literature

trending toward significancep = 0.071.4× alpha
Ventral prostate lobe mass decreased in the 1 mg/kg PCB treatment group compared to the 0.1 and 6 mg/kg PCB treatment groups with no changes in any other prostate lobes ( Figure 1 A–C); however, when normalized to body mass, there were no significant differences in prostate lobe wet weights between treatment groups, though the same ventral prostate phenotype was trending toward significance with p = 0.07 ( Figure 1 D–F).
trending toward significancep < 0.0711.4× alpha
2A ) revealed a non-significant (though trending toward significance) difference in mean PSC values for the Transfer run (TR) and for the last run with the active rtfMRI-nf (A2) (TR vs A2: t (17)=1.92, p < 0.071, d = 0.45), and a significant difference in mean PSC values for the TR and for the last run with the sham rtfMRI-nf (S2) (TR vs S2: t (17)= 3.38, p < 0.004, d = 0.80).
trending toward significancep = 0.0781.6× alpha
As such, we repeated the logistic regression excluding these specific subgroups (remaining n = 989) and found that SO 1000cs remained a significant independent variable for unexplained visual loss relative SF 6 (p < 0.001) and SO 5000cs trending toward significance (p = 0.078) (Additional file 2 : Table S2).
trending toward significancep = 0.0881.8× alpha
The linear mixed model M5-(described in the Methods “Statistical analyses”)-based post-hoc comparisons of 31 P MRS parameters in the hippocampus, the motor cortex, and the premotor cortex between MMD patients and control family members revealed significantly ( p < 0.05) decreased levels of PCr (phosphocreatine)/ATP and PCr/P i (inorganic phosphate) and increased (trending toward significance; p = 0.088) levels of P i /ATP in all selected brain areas of MMD patients (Table 1 and Fig. 6 ).