Effect of skull density ratio, dose volume, lesion size, and normative tractographic coefficients on QoL outcomes Stratified by patient QoL assessment at last follow-up, the skull density ratio (SDR) of “worse” patients was highest (0.64 ± 0.03), followed by “better” (0.58 ± 0.02), and lastly “same” (0.53 ± 0.03), with the group differences trending toward significance (Kruskal-Wallis H = 4.7705, p = 0.09).
The increase of the proportion of c‐Fos‐positive cells in the TXL_10_50 group was trending toward significance to that in the PTZ‐control group ( p = 0.093; two‐tailed Mann–Whitney U test).
Also in keeping with the pilot nature of this study, results of statistical analyses are described in terms of being statistically significant ( p < 0.05), trending toward significance ( p < 0.10), and not significant ( p > 0.10).
Exact p values are provided if significant (p<0.05) or trending toward significance (0.05<p<0.1).
Statistical significance was assumed when p ≤ 0.05, trending toward significance at p ≤ 0.10.
The variables significantly associated, or trending toward significance ( p < 0.1), with non-responsiveness to splenectomy in univariate analyses were combined into a prognostic score.
We used a significance level of P ≤ 0.05 and trending toward significance at a level of 0.05 < P ≤ 0.1.
10 μM NPA-, 50 μM NPA-, and 100 μM NPA-treated gametophytes exhibited a median RMR comparable to the DMSO solvent mock, although the 100 μM NPA-treated group was trending toward significance ( p = 0.15) in comparison to either of the lower concentrations of NPA ( p > 0.99) ( Figure 6 k).
Interestingly, while baseline [MBNL] inferred did not contribute significantly to the predictive power of either model, it was trending toward significance in the model for adults, but not in the model for CDM ( p = 0.1675 & p = 0.7125, respectively).
Greater EC FTP slope was not correlated with NM decline in the PiB– group but was trending toward significance in the PiB+ group (PiB–: r = −0.18, P = 0.25; PiB+ r = −0.3, P = 0.08; Figure 2B ).
For this reason, relationships with a p-value between 0.05 and 0.10 were additionally considered as trending toward significance [ 36 ].
The negative relation was particularly pronounced when considering the specific social media platforms of Twitter and Facebook (though this negative relation was only trending toward significance for Facebook).
Clinical trials for AD therapeutics have commonly used some version of the ADAS‐Cog at longitudinal visits to assess the efficacy of the treatment in slowing cognitive decline; for nearly two decades, trials of amyloid beta (Aβ)‐targeted therapies have failed to show efficacy, 28 although some have shown results in the ADAS‐Cog that were trending toward significance. 29 If language item scores are reliable and most heavily influenced by the progression of mild AD, the clinical trial data might be reassessed post hoc using language subdomain items, or specifically “comprehension of spoken language,” as most items from the other subdomains were less reliable, and their reliable information was more heavily related to interindividual trait differences.
ALT levels were decreased in both groups from 25.1 to 22.9 U\L in the statin group, with a p -value of 0.09 trending toward significance, and from 27.2 to 25.2 U\L in the no statin group.
23 , 24 The difference in tobacco use is only trending toward significance but this is likely the result of the limited number of patients included in this study.
When controlling for Wave 2 scientific literacy scores, we see Wave 2 home science environment predicting Wave 4 scientific literacy scores, B = 0.06 (SE = 0.03), p < 0 .05, and trending toward significance for Wave 5 but not at Wave 3.
In the 40-mmHg trial, a single fenestration resulted in a mean fluid egress of 213.75 μL, two fenestrations 293.75 μL; not significantly different with a P -value of 0.08, but notably trending toward significance.
Values of P > 0.05 and P < 0.1 were referred to as trending toward significance.
Significant results are shown in white, values trending toward significance in light gray, and non-significant results in dark gray.
Finally, our failure to find a lexicality effect in pMTG for tongue twisters suggests that evidence for such an effect trending toward significance in prior research may reflect a false positive result.
With DAPT treatment, we observed a significant increase in the % NEUROD1 + cell population of the MEL1-INS GFP/w cells and an increase trending toward significance in the % NEUROD1 + population of the H1 cells (Figs. 4 A,B,D,E, and S7 D).
Under the stringent binding assay involving incubation in 1.5 M NaSCN, the avidity of the antibodies elicited by SAS- adjuvanted JRFL-L60-C3d trimers was higher and trending toward significance than that from SAS- adjuvanted JRFL trimer- vaccinated mice (G4 vs.
Although only trending toward significance, likely due to the low number of patients in this subgroup analysis, these data suggest that there may be a clinically meaningful benefit from the IO score or the IO + /TMB high model (IO HR 0.3001, 95%CI 0.0773–1.165, p = 0.0819; IO + /TMB high HR 0.3432, 95%CI 0.09792–1.203, p = 0.0946) (Figure S2A).
We also report p-values <0.10 as a trending toward significance.
A probability level of p < 0.05 was defined as statistically significant and a probability below 0.1 was defined as trending toward significance. 3.