Excerpts

Additionally, a highly significant Spearman’s correlation was found between the reciprocal expression of SST mRNA and SST1 mRNA in the control group (R = 0.69, p < 0.05) ( Table 4 ). 3.3.

The remaining analyzed risk parameters—T and N pathological stage, and LVI and PNI status—did not show a statistically significant association with overall survival time by univariate analysis ( p > 0.05), while received adjuvant therapy almost reached statistical significance ( p = 0.05).

Experiencing TRAEs of grade 3 or higher showed a trend towards worsening OS (HR 1.79, 95% CI 1.00–3.21, p = 0.05) and PFS (HR 1.53, 95% CI 0.90–2.59, p = 0.12).

Even though these differences were not statistically significant, there was a clear trend towards a delay in the liver tumor colonization in Id1 -deficient LLC-tumor-bearing mice ( p > 0.05).

For Audencel patients, a similar trend was visible; however, it did not reach statistical significance ( p = 0.05, Figure 4 ).

Statistical results were considered significant (*) or highly significant (**) at p < 0.05 and p < 0.01, respectively. 3.

A negative correlation trending toward significance was observed between the percent tumor volume of the HV-HC habitat and the percent tissue area of necrosis identified from H&E-stained slides ( r 2 = −0.47, p = 0.05, Figure S6B ).

BRAF mutation burden ( p = 0.001- post estimation by Pearson χ2 goodness-of-fit test p = 0.4) depended significantly on age at diagnosis ( p = 0.001) and in borderline significance on the anatomical site where CM developed ( p = 0.05).

The interaction between tobacco consumption and GDM was non-significant ( p = 0.60) but the interaction between age and GDM was marginally significant ( p = 0.05).

According to other studies [ 36 , 37 ], our patients whose tumor occurred with obstruction or perforation showed a worse DFS compared with the other tumor manifestations, although with a trend towards significance (HR = 2.65, 95% CI 1.00–7.01, p = 0.050).

The baseline analysis demonstrated the marginally significant linear association of NTG incidence with the gamma dose, taking into account non-radiation factors and neutron dose; ERR/Gy = 0.53 (95% CI 0.01, 1.68; p < 0.05) ( Table 4 and Figure 1 ).

Second, there are genes (seen in green) that show a moderately significant change in expression ( p -value < 0.05) and an absolute value of log 2 FoldChange > 2.

Patients who had not received (β = 1.05) or who completed RT (β = 1.08), showed a better SumSc score compared to those who were receiving RT, but with a borderline significance ( p = 0.05) ( Table 5 ). 4.

ADC Values and Progression-Free Survival There was a marginally significant association between nADC min and progression free survival (PFS) ( p = 0.05, HR = 0.602, 95%CI = 0.344–1.053).

SDRs due to ovarian cancer showed a decreasing trend between 2007 and 2021 (APC = −0.5%, p < 0.05).

An absence of primary osteosarcoma metastases was of borderline significance for both overall ( p = 0.050) and event-free ( p = 0.063) survival. 4.

We observed statistically significant differences in age ( p < 0.001), mortality (P-POSSUM; p = 0.027) and almost significant differences in the history of previous surgeries ( p = 0.05).

One study showed a trend toward increased risk with prior WBRT ( p = 0.05).

showed a potential reduction in the mortality rate in the CGA-driven intervention group, but the study failed to reach significance ( p = 0.05) [ 25 ].

In patients with UICC stage III disease, we registered a slightly non-significant improvement in the disease-free survival (UICC III: p = 0.050).

A constant increase in intracellular production was observed in CD3, CD3/CD4, and CD3/CD8 cells, which became highly significant already at T3d for IFNγ ( p < 0.05) and at T7d for TNFα ( p < 0.005), and increased further at later time points ( Figure 4 A,B).

Model 4 constrains the MZ pair correlation to be twice the correlation for DZ and sister pairs combined, and the comparison of the log-likelihoods with those of Model 2 shows that, except for Cirrocumulus , there was at least nominally significant evidence that the MZ correlations were more than twice the corresponding correlations for DZ and sister pairs combined (all p ≤ 0.05).

Additionally, most of the detected miRNAs, including the selected miR-150-5p and miR-23b-3p, did not reach the conventional significance threshold of adjusted p -values < 0.05, but they showed a trend toward significance with p < 0.05.

In total, 18 (CRNN, DDX3X/DDX3Y/DDX4, DESP, DHB4, DSG3, ELAF, GBP6, K1C14, K1C16, K2C1, LEG7, PKP1, PKP3, PLAK, SPR1A, SPR1B, SPR2A, and TGM1, Figure 2 ) of these 207 proteins were found to have nominally significant ( p < 0.05, Wilcoxon ranked sum test) differences in abundance levels between cases and controls.

For overall survival, only the detection of ctDNA at baseline emerged as independent factor associated with shorter OS (HR: 2.3; 95% C.I.: 1.1–5.1, p = 0.041), while only gender had a marked trend (HR: 2.0, 95% C.I.: 1.0–4.1, p = 0.05). 4.