Excerpts

To note, we do not see a significant change in protein turnover between no recovery and 4 h, and a weakly significant difference between 30 min and 4 h (Dunn ́s, p < 0.05).

On the other hand, when we used the ACh stimulation protocol ( Figure 2 e–h), the average distance between DBH centroids and the nearest α3β4 nAChR centroids (184.0 ± 50.2 nm) was not only significantly lower than the average one when compared with a random simulation for α3β4 nAChR structures (605.7 ± 9.7 nm; p -value < 0.0001, Figure 2 i), but also showed a moderately significant average distance reduction to that obtained for the K + stimulated assays ( p -value < 0.05).

Any difference was considered significant and highly significant at p ≤ 0.05 and p ≤ 0.01, respectively.

In JB6 cells, the administration of 20 μg/mL and 40 μg/mL LQ interventions significantly decreased the level of TNF-α ( p < 0.05) ( Figure 3 D); the administration of 40 μg/mL LQ interventions significantly decreased the level of IL-1β ( p < 0.05) ( Figure 3 E); and the administration of LQ interventions failed to significantly decrease the level of IL-6, but it also followed an increase in dose and showed a decreasing trend ( p > 0.05) ( Figure 3 F). 2.4.

Although not statistically significant, there was an obvious trend with worse OS in women with EC expressing a high NCL quick score (≥6), than in women with low NCL quick score (<6) ( p = 0.05) ( Figure 2 C), with median survival in those with a low NCL quick score (<6) at 96 months when compared with the 30 months median survival in those with high NCL quick score (≥6).

demonstrated an increasing trend ( p < 0.05, Figure 3 B,D).

Borderline significance was found for rs1014290 and rs12498742 in GLUT9 during pregnancy ( p = 0.050 and p = 0.096, respectively, Kruskal–Wallis ANOVA).

In contrast, only a slightly significant recovery of movement was guaranteed by 200 μM ERN on α-syn::YFP nematodes compared to untreated worms ( p < 0.05 for 200 μM ERN) ( Figure 5 B).

The opposite was also observed in tolerance with an evident trend towards lower K/T ratios and higher STF levels in the tolerant recipients ( p < 0.05 by t -test).

Analysis of clear cell and endometrioid ovarian cancer subtypes revealed nearly significant upregulation ( p = 0.05).

Data analysis for ACR70 showed a favorable trend toward anti-IL-17 (OR 2.62, 95% CI 1–6.89, p = 0.05, I2 15%).

In the SPR experiments, a statistical trend was considered to be statistically significant if its p -value was 1 > p > 0.05.

Although no individual lipid species remained significant after Benjamini–Hochberg false discovery rate correction, the lipid alterations showed systematic class-level trend which was significant for several lipid classes under Fisher’s combined probability test (as seen in Figure 1 ), and therefore, species-level results are still reported as nominally significant (unadjusted p < 0.05).

An almost significant increase ( p = 0.05) was found in the activation of p38, downstream of Y1214 signaling.

Although odds ratios associated with the CC genotype were between 1.77 and 2.26 indicating an approximately doubled risk of breast cancer, these observations did not quite attain significance at the p < 0.05 level, which may be due to the small number of CC patients ( Table 2 ).

Carlo permutation tests showed that the first and all canonical axes were highly significant ( p < 0.05), suggesting that these physico-chemical parameters played important roles in driving the shifts of the fungal community composition.

A total of 205 risk factor associations were found to be nominally significant ( p < 0.05).

Figure 6 c shows the data for eIF2α protein expression, indicating that the HCD groups exhibited an increasing trend compared to the SD group, whereas the HCD + EA group showed a decrease in expression compared to the HCD group ( p > 0.05).

2003 [ 38 ] showed no differences between cases and controls, in comparison of genotype frequencies except for a modestly significant difference for the 8393 ( Hin dIII) variant ( p = 0.05).

When we divided the cases into two groups according to the timing of the initiation of PEG-IFN (N=32, each group), mildly significant differences ( p < 0.05) were found in some clinical characteristics between the patients in the first-half group and those in the second-half group ( Supplementary Table S3 ).

) dosing with 10 mg/kg a highly significant ( p < 0.05, n = 6, repeated measures ANOVA, Figure 1 B) level of BBI-11008 (post hoc tests at single time points: * p < 0.05, n = 6, Figure 1 B) can be measured from dialysate of the DLS.

In addition, il-6 and il1-β are precursors of hamp ; therefore, the expression levels of hamp1 and hamp2 in the 0-R group showed an increasing trend ( p < 0.05).

Circulating levels of FSH, which plays a role in limiting thermogenesis and WAT browning in mice [ 17 ], trended downwards in female Trsp Agrp KO mice, although the change was not quite statistically significant ( p = 0.05).

In line with these results, there was a highly significant correlation between sequencing data and qPCR output (normalized reads vs. normalized Ct) for the four upregulated microRNAs (all with p < 0.05; Spearman correlations) ( Figure S4 ).

Moreover, it was found that the HIF2α, BNIP3L, Beclin1, and LC3-II mRNA expression levels were almost significantly lower in the cerebral cortexes, hippocampi, thalami, medulla oblongatae, and cerebella of the low-altitude yaks compared to the high-altitude ones ( p < 0.05).