Excerpts

The analysis showed that only the presence of cutaneous symptoms is a significant positive predictor of BST; there was also a positive trend for the KIT p.D816V mutation ( p = 0.053). 3.

Among the NTRs, there was a borderline significant difference (two-tailed independent t -test, p = 0.053, n = 6) in the level of p75NTR expression in the MOE with a higher level in vehicle-exposed TRPM5-GFP than in Skn-1a −/− mice, implying that TRPM5-MCs might, to some degree, modulate p75NTR expression.

Although not statistically significant, higher TGF-β levels at three months post-treatment initiation showed a trend toward association with worse outcomes [mean (standard deviation) 43.2 (28.2) pg/mL vs. 29.6 (46.9) pg/mL, p = 0.053] ( Figure 5 ).

In contrast, including plasma samples from BC patients in the statistic tests introduced a certain degree of noise and the mutation c.742C>T in sample 079MS was not detected despite being close to significance ( p -value = 0.053) ( Table S4 ).

Notably, when comparing ether-lipid-deficient mice against WT, wall stress at end-diastole was significantly increased at the septal wall ( Figure 3 C) and almost reached statistical significance for the free ventricle wall ( p = 0.053; Figure 3 D).

However, it should be mentioned that borderline significance was obtained for alleles of POLG c.-1370T > A (rs1054875) ( p = 0.053). 2.4.

Regarding the number of granulocytes, in AD it was much lower than in HCs, and the result was very close to statistical significance (U = 418; p = 0.053; p (BH) = 0.053; r G = −0.23).

Although the time course of left ventricular ejection fraction (LVEF) showed a trend toward reduction in the sham compared to the V-V ECMO group after the end of the experiments, the difference failed to reach statistical significance ( p = 0.053). 2.3.

Post hoc comparisons also revealed that J+A rats covered less distance in the open quadrants of the EZM compared to control ( p = 0.003), showed a borderline significant reduction compared to juvenile stress exposed (juv stress; p = 0.053), and showed a significant reduction compared to adult stress exposed rats (adult stress; p = 0.014) ( Figure 3 B).

The hsa-miR-155-3p target SP4 showed a trend for down-regulation (FC = 0.43, p = 0.053). 3.

The results show that the average NE concentration was higher after WECS treatment, at the margin of statistical significance ( p = 0.0531) ( Figure 4 A).

In particular, miR-101 ( p -value = 0.0023) and miR-26b ( p -value = 0.0016) expression levels were significantly lower in tumors than in normal tissues, while miR-200c showed borderline significance ( p -value = 0.0537). 2.3. miR-101, miR-26b, and miR-200c are Confirmed to be Significantly Downregulated in IGC The levels of the 3 miRs differentially expressed in the exploratory case series were analyzed in the case series of 33 IGC patients by RT-qPCR using specific TaqMan gene expression assays.

Vglut2-cKO mice showed a trend of increased episode number of wakefulness ( p = 0.0539) and NREMS ( p = 0.0786) ( Figure 5 C), whereas the average episode duration of NREMS was shorter in Vglut2-cKO mice than in WT littermates ( Figure 5 D).

In women, however, the Friedman ANOVA test did not show statistically significant differences, although the p -value approached significance ( p = 0.054), with Kendall’s coefficient of concordance at 0.18.

A nearly significant inverse correlation was observed between circulating APC and cfDNA levels in controls ( p = 0.054), the neutrophil activation marker associated with the greatest increase in thrombotic risk.

Cosinor analysis detected no significant rhythmicity in the 6-meals-a-day groups ( p = 0.139) and a marginally significant rhythm in the ad libitum group ( p = 0.054) ( Figure 4 D). 2.7.

This lower level is almost significant in normal glucose with MGO (11.478 ± 0.725 ng/μg; p = 0.054).

We observed a statistically significant association for the GC rs7041 polymorphism in the additive ( p = 0.028) and allelic ( p = 0.031) models, and a tendency toward statistical significance in the dominant ( p = 0.054) and genotypic ( p = 0.088) models ( Table S5 ).

Additionally, there was a marginally significant increase in I-FABP levels in lean patients when compared to non-lean individuals ( p = 0.054, Figure 7 a).

While OGA expression showed an increasing trend in aortic lysates from hyperglycemic vs. non-hyperglycemic smOGT WT mice, this difference did not reach statistical significance ( p = 0.054).

In the GBM cluster, high and low CKAP2L expression groups’ curves only revealed borderline significance ( p = 0.054). 2.2.

The pre-administration baseline AαVal541 level of the AATD patients before they received their first AAT augmentation therapy showed no correlation with baseline pulmonary function, although diffusion capacity (KCO) showed a trend to a negative correlation with baseline AαVal541 level (Spearman’s correlation coefficient—0.624, p = 0.054). 2.4.

post stimulation 18.54 ± 5.25 ng/mL, p = 0.002), with a statistical trend during stimulation (baseline vs. stimulation 23.64 ± 7.84 ng/mL, p = 0.054) ( Figure 4 ). 2.2.4. 5-HIAA Levels Were Selectively Reduced in DYT1 KI Mice During and After Optogenetic Inhibition of PV+ FSI Serotonin (5-HT) was below the limit of detection (< LOD), but its metabolite 5-hydroxyindolacetic acid (5-HIAA) was reliably quantified.

In particular, OUT 3 showed a statistically significant reduction ( p = 0.048), while OTU 2 and OTU 4 approached significance ( p = 0.054 and p = 0.057, respectively).

The baseline concentration of the biomarker higher than 212 μg·mL −1 was significantly associated with increased risk of disease progression (PFS HR 2.5 (1–6), p -value = 0.042, Figure 3 F), and there was a borderline significant association with increased risk of death (OS HR 2.6 (0.98–7.1), p -value = 0.054, Figure 3 H).