Barely Significant

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a statistical trendp < 0.081.6× alphagold
In r-axSpA, there was a statistical trend for higher VEGF levels in A2AP 6Trp carriers (6Trp: 412 ± 251 pg/mL; 6Arg/Arg: 367 ± 253 pg/mL; p < 0.08) and in nr-axSpA patients, this difference was more pronounced (6Trp: 524 ± 429 pg/mL; 6Arg/Arg: 379 ± 335 pg/mL; p = 0.02). 2.3.
a nonsignificant trendp = 0.081.6× alphagold
If the cohorts were analyzed independently, the significances remained for the Lund cohort, but only mutational status, not histological type, correlated significantly to PD-L1 expression in the Halmstad cohort (in the Lund cohort, there was only a nonsignificant trend for lower PD-L1 in cytology than biopsies, p = 0.08). 2.3.
borderline significantp = 0.08051.6× alphagold
The correlation was weak and borderline significant according to the Pearson correlation coefficient ( r P = −0.115, p = 0.0805), but significant according to the Spearman correlation coefficient ( r S = −0.157, p = 0.0163), possibly indicating a homeostatic effect of increased heterozygosity.