Excerpts

The expression of Bcl-2 was lower in the P-10-M group than in the P-10 group ( p < 0.05) and has a decreasing trend compared with the P group (0.05 < p < 0.1), indicating that cell apoptosis can be promoted in HPC GCs by overexpression of MAPK12 . 2.10.2.

PD-NC) and PLA score, as independent variables, and the latter was confirmed as a significant predictor of ΔMMSE ( p = 0.027), whereas a non-significant trend toward significance ( p = 0.1) was found for ΔMoCA.

Additionally, dietary supplementation with magnolol showed an increasing trend in the serum concentrations of methionine, aspartate, and cysteine ( p < 0.10).

A summary of the numbers of biochemicals that achieved statistical significance ( p ≤ 0.05), as well as those approaching significance (0.05 < p < 0.10), is shown below.

The threshold for statistical significance was set at * p < 0.05, while a difference approaching significance was indicated at i p < 0.1 for all analyses. 5.

While the Luminal B poor-prognostic gene set showed a trend toward worse outcomes (HR = 1.663, 95% CI: 0.9–3.074), this association did not reach statistical significance (Log-rank p = 0.1; Figure 6 D).

Of the 19 miRs consistently expressed across all four biological repeats, it was shown that 14 were significantly downregulated upon 4 h PLK1i, with an additional 3 trending towards significance ( p ≤ 0.1) and 1 unchanged (miR-652-3p) ( Figure 3 E).

Although a clear trend was observed, the difference did not reach statistical significance (exact Fisher’s test: p = 0.10).

Carfilzomib alone or DC101 alone also prolonged the survival compared with the control, with borderline significance (carfilzomib; p = 0.1, DC101; p = 0.07).

The female offspring glucose levels also increased (8%; p < 0.05) by the maternal administration of methyl donor substrates, while total cholesterol also showed a trend to increase in these groups (10%; p < 0.1).

Several genes of the immune and inflammatory response showed a trend of decreased expression ( p < 0.1) in the presence of low doses of DON, Il-10, CXCL8, IFN-γ, and TNF-α ( Figure 5 ).

However, this difference was only marginally significant ( p < 0.1, using Student’s t -test). 2.4.

Early-life intervention with FMT-CS significantly increased the Chao1 estimator and ACE estimator of fecal microbiota at the age of 7 d ( p < 0.05) and 27 d ( p < 0.01) in comparison with those in control piglets, and showed a trend to increase the Shannon diversity index at the age of 27 d (0.05 < p < 0.1).

Another study observed a nonsignificant trend for higher expression of let7-c in LCLs from ten patients with BD nonresponders compared with ten responders to lithium (fold change [FC]: 1.6, p = 0.1) [ 97 ].

The ISF/SF showed a trend toward affecting plasma interleukin-2 (IL-2) levels in neonatal piglets ( p < 0.10). 2.3.

However, the real-time PCR (RT-PCR) results of PCNA and CCND1 revealed borderline significant differences between the HBM and LBM groups ( p < 0.1).

However, no significant association with DFS was observed, although the results showed a trend toward such a relationship ( p < 0.1).

The concentration of diamine oxidase (DAO) showed a decreasing trend in response to magnolol supplementation ( p < 0.10).

In our analysis, there was a nearly significant elevation in APP WT beginning at 3 h ( Figure 3 e, p = 0.10), and the activation was sustained at a similar level throughout the experiment (approximately 3–4-fold upregulation, 0.07 < p < 0.1).

Notably, other features such as number of branches and number of slab voxels had near-significant increases in the sham group (0.05 < p < 0.1). 2.3.

A nonsignificant trend towards higher levels of VDR mRNA was observed in the endometriosis group ( p = 0.10).

Univariate variables with a trend towards significance ( p < 0.10) and after testing of the proportional hazards assumption were used for analysis in the multivariate model.

In addition, 11 compounds showed a trend towards a change by hRSV ( p < 0.10), of which eight were increased and three were reduced.

p -Values ≤ 0.05 were considered statistically significant and values approaching significance ( p < 0.10) were reported as well.

Transfection of [m6A1]miR-494-3p resulted in a significant increase in mRNA expression of LRP6 and AVCR1 and a trend towards significance ( p < 0.1) of FGFR2 and FZD2 compared to its unmethylated equivalent, indicating a decrease in target repression after [m6A1]miR-494-3p transfection ( Figure 6 B,E–G).