Barely Significant

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a trend towards significancep = 0.061.2× alpha
The use of b/tsDMARDs was significant in the SCORE2 algorithm in the listwise analysis [coefficient −0.006 (95% CI −0.011 to −0.0016) p = 0.010] and showed a trend towards significance in the computation analysis [coefficient −0.003 (95% CI −0.008 to 0.0002) p = 0.06] ( Table 4 ). 5.
did not reach statistical significancep = 0.061.2× alphaplainly factual
showed a trendp = 0.061.2× alpha
Although patients with NLR ≥ 2.5 showed a trend toward more frequent postoperative complications (59.8%) compared to the NLR < 2.5 group (40.2%), this difference did not reach statistical significance ( p = 0.06).
borderline significancep = 0.0601.2× alpha
In the multivariate analysis, only age (4% risk increase) and preoperative diastolic ABP (risk decrease of 6% with higher diastolic ABP) remained significant; however, incidental diagnosis showed borderline significance (2.8-fold risk increase; p = 0.060).
borderline significancep = 0.061.2× alpha
Interestingly, secondary analysis of data from a study of van Grootven and colleagues [ 47 ] revealed that among 86 patients aged 80 ± 7 years undergoing orthopedic surgery, the lowest intraoperative diastolic BP was the protective factor for POD (OR = 0.92; 95%CI 0.85–0.99, p = 0.03) and the protective impact of the highest systolic BP was of a borderline significance (OR = 0.97; 95%CI 0.94–1.0; p = 0.06).
a trend towards significancep = 0.061.2× alpha
A greater affectation was found in patients with MHE compared to NMHE in the modality of conduction heat pain detection in the foot, with a trend towards significance ( p = 0.06) in the sensitive sensory threshold value (0.5 JND) and a significant increase in the maximum value reached during the heat pain test (5.0 JND) ( p = 0.04).