Excerpts

Evidence of association was also inferred when a locus had marginally significant signals in association testing and meta-analysis.

Variants for which the Benjamini-Hochberg false discovery rate (FDR) was less than 0.05 and P > 5e-08 were considered of marginal significance.

Temporal dynamics in tidal flat width and the underlying elastic responses Tidal flat width shows a clear trend of overall erosion (Fig. 3a, c ).

In particular, the PSS of WenHai shows a positive trend for all the ocean variables as the forecast lead time increases, suggesting that WenHai can capture the temporal variations of the eddying ocean reasonably well.

Due to ion-selective accumulation, the osmotic potential ( V os ) exhibited an increasing and then a decreasing trend versus the concentration gradient ( C H /C L ), while the positive osmotic current ( I os ) increased from 22 to 47 nA, demonstrating a cation selectivity at pH = 3.5 (Fig. 5c ) 43 .

Pathway enrichment analysis demonstrated highly significant (q < 1e −30 ) enrichments in downregulated pathways associated with “mitochondrial respiratory chain”, “mitochondrial electron transport” and “mitochondrial ATP synthesis” (Fig. 2D ).

This is filled in the hydrogenated reaction and only a barely significant dip at large internal excitation is remaining.

The complex viscosities of r-PAR ranged from 8200 to 2800 Pa s at temperatures between 280 °C and 320 °C, showing a decreasing trend as the temperature rose.

Post-hoc t -tests showed that the ripple rate of the strengthening condition was significantly higher than that of control conditions ( t (10) = 2.31, p = 0.043), and showed an increasing trend than that of the decaying conditions, but did not reach statistical significance ( t (10) = 2.174, p = 0.054).

Statistical significance was set at p < 0.05, with p < 0.005 considered highly significant.

While NET39 depletion alone caused only a subtle shift of the MyoD1 locus towards a more central position within the nucleus, additional depletion of Tmem38a induced a statistically highly significant change in the localization of MyoD1 towards the nuclear interior, which was further enhanced upon deletion of WFS1 (Fig. 4b , left panel).

Furthermore, the slope of activity preceding locomotion offset differed markedly between the two subtypes: Kremen1 + dSPNs exhibited an increasing trend (positive slope), while Calb1 + dSPNs displayed a decreasing trend (negative slope) (Fig. 3m ).

Most production fields in China showed an increasing trend of CH 4 emissions, especially in Northwest, Southwest, and North China, where emissions increased by 1.4 TgCH 4 , 0.5 TgCH 4 , and 0.4 TgCH 4 , respectively, from 2000 to 2022.

Notably, although the DNA sequences of the CTCF sites within the PCDH -β locus are identical between humans and macaques, the human CTCF sites within the PCDH -β locus showed a trend of increasing DNA methylation compared to macaques (Fig.

Conversely, expanding spatial frequency bandwidth did not further improve orientation discrimination performance and even showed a trend towards reduced performance with higher spatial frequency bandwidth (Fig. 7d , percentage of correct trials: narrow (0.004 cpd) = 72.53% ± 2.85%; mid-range (0.04 cpd) = 69.18% ± 2.12%, Wilcoxon signed rank test against narrow percentage of correct trials, p = 0.79; broad (0.4 cpd): 65.34% ± 3.60%, p = 0.29, mean ± s.e.m., n = 24, 16 and 18 sessions for each condition from 6 mice).

When analyzing the average population activity across multiple 10-min sessions, we found that the switch from water to saccharin, and water to quinine-added water, did not significantly change activity (although the latter was close to significance).

Notably, PD-1 expression was significantly upregulated in tumors after neoadjuvant Aumolertinib treatment compared to baseline, with an increasing trend in PD-L1 expression (Fig. 4f ).

A notable trend in this integration is the use of smartphone or tablet-based digital devices to read test results 75 – 77 .

2BP treatment of healthy cultures showed a trend towards decreased DLK palmitoylation in axon fractions but this did not reach statistical significance.

We treated detached cells with a series of concentrations of putrescine and observed an increasing trend in the total polyamine level in the detached cells (Fig.

A clear trend is visible between thermal conductivity and lifetimes of the sesquioxides indicating scattering rate as the dominant factor leading to the decrease in thermal conductivity.

Moreover, we observed a number of morphological features in the upper layers: Neurons in layers 2/3 showed a trend of a decreasing width of their dendritic arbor and a smaller tuft with increasing cortical depth.

In JJA, a negative trend in WSC is observed over the northeastern Weddell Sea (Fig. 7a ) and likely contributed to 100–500 m subsurface warming and sea ice decline there (Figs.

Additionally, we noted a positive trend in the fraction of OVA-specific PEX CD8 + T cells in the IiOVA mid dose compared to the high dose-treated animals.

Myelination in GA-Nes mice was not significantly reduced at this young age compared to littermate controls, although there was a small trend (Fig.