America showed no trend in percent fire-induced forest loss, and Africa showed a decreasing trend (Supplementary Fig. 3a ).
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Trend analysis of these short-term records showed an increasing trend in percent fire-induced forest loss in Eurasia, the western US, and Australia.
During marine isotope stage 5 (MIS 5), three negative peaks in the loess δ 13 C IC exhibit a decreasing trend from MIS 5e to MIS 5a, corresponding to changing summer insolation maxima.
When we plotted the ED 50 values for morphine analgesia in WT, S375A, 10S/T-A and 11S/T-A mice against their respective ED 50 values for respiratory depression and constipation we found highly significant correlations (Fig. 4 , Supplementary Table 1 ), suggesting that both opioid effects cannot be uncoupled.
We can summarize these results by asking: What is the percentage of the ocean area showing a significant trend at different intervals over the 21st century?
a strong trendgold
Where some of the reflectance bands do not show a strong trend, they will dampen the signal of the change in true colour.
a positive trendgold
In addition to ADCVI activity, we found a significant correlation with anti-Env CD4+ T-cell response after the second cycP-gp120 immunization, as well as a positive trend in anti-V2 antibodies with delayed SHIV acquisition, supporting recent studies highlighting the importance of V2-specific antibodies in the human efficacy trials 34 , 38 , 54 as well as both V2-specific antibodies and T-cell responses in non-human primate studies evaluating poxvirus/gp120 vaccination 55 , 56 .
Persistence of an intermediate state envelope trimer in a very early transmitted founder virus described here might be significant.
a positive trendgold
Some studied species show a positive trend: rates of EPP were higher in males with larger repertoires (great reed warblers 24 ) or with increased song diversity (reed bunting 32 ).
an overall trendgold
Our functional characterization of these monoclonal antibodies revealed an overall trend that matched those observations on polyclonal allosera.
Analyses of long-term measurements at NHL stations, Point Barrow (BRW, Alaska) and Alert Nunavut (ALT, Canada), reveal that this seasonal cycle has changed over time, dominated by a decreasing trend in the annual CO 2 minimum (Fig. 3a, b ).
After stimulation with K562 or 772.221 target cell lines, infant lamina propria-derived NK cells showed a trend towards enhanced degranulation compared to adult NK cells (Supplementary Fig. 5 ).
In the mixed effects model, this result was marginally significant in PRc and nonsignificant in PHc and should be interpreted with caution.
Wing pigmentation was noted for males and females from all species (10.17617/3.1D; 08 Wings), with examples shown for most wings with any spots or pattern, where there was a significant trend of wing pigmentation being correlated with larger eye species relative to antennal size (Fig. 4c ; Supplementary Figure 3H ).
Furthermore, we used TPP to investigate how the addition of 10 mM ATP affected the thermal stability of solubilized proteins (Supplementary Data 8 ) and observed a significant trend for thermal destabilization compared to the vehicle condition (Fig. 3f ).
Importantly, three of these groups showed distinct and highly significant functional enrichments.
3d ) and a non-parametric analysis of variance showed this effect to be highly significant across all mouse populations tested.
a clear trendgold
The development of the peak heights do not follow a clear trend (insets of Fig. 2 ) and for nearly all datasets they remain stable over time (see Supplementary Fig. 5 for full distributions, the exception of Wikipedia is discussed in Supplementary note 1).
Moreover, there is a highly significant correlation between NGF and serotonin in human and they are markedly upregulated in IBS-D patients.
Excluding the previously published datasets, 56 of the 118 available variants were at least nominally significant in a meta-analysis of HUNT and MGI alone (Supplementary Data 6 ).
a strong trendgold
Principal component analysis of relative metabolite abundance per cell revealed a strong trend across the 54 cell lines (PC1, 58.9% explained variance, Supplementary Fig. 2 ), which strongly correlates with cell line volumes derived from cell diameters measured in ref. 66 as well as with the herein determined adherent cell size area (Supplementary Fig. 2 , see Supplementary Note).
only marginally significant) moderated the effect of stimulus history on observers’ causal prior, i.e. their tendency to bind audiovisual signals (Fig. 7b ).
NP) and showed a trend of a higher number of persistent clones ( P -value [linear regression] = 0.09).
Similarly, although altitudinal range is associated with language diversity at high resolution with marginal significance, there is no evidence that this is caused by isolation, as altitudinal range does not result in reduction in speaker population size, even when controlling for population density (Table 3 ).
However, while multiple nominally significant cis -eQTLs were present, nearly half of all loci had no evidence of cis -eQTLs in the sample sets used.