Excerpts

sQTLs that were also eQTLs First, GTEx variants were filtered for those that were both nominally significant sQTLs (.v8.sqtl_signifpairs.txt) and nominally significant eQTLs (.v8.egenes.txt) in the same tissue (GTEx browser) .

Sedimentary archives from the ECS reveal a striking divergence: while δ 13 C org exhibits an increasing trend, 10 of 13 cores show coherent declines in δ 15 N from the early 1900s to present, with an average rate of −1.09 ± 0.48‰ per century (Supplementary Figs. 8 and 9a–b ).

Conversely, a weak trend between MW and toxicity suggests that heavier compounds are less toxic.

8E ), this was not the case in most excitatory neurons, where it instead showed a trend in the other direction (Fig. 8C ).

We also evaluate the macro-F1 score, which exhibits an overall trend consistent with that of weighted accuracy.

2e shows the winter NPP calculated in the grid with the highest observation frequency, displaying a positive trend of winter NPP rate.

In contrast to the climate models, historical observations suggest that the ITF transport showed no significant trend during the past century or even an increasing trend during the recent decades when the ocean has been rapidly warming 11 , 30 , 31 , 33 , 34 .

Many of the genes involved in the 50 highest ranking triples have already been linked to AML in the literature (see SI for Table S3 for a list of highly significant triples and Table S4 with links to the literature associating the involved genes with AML).

In addition, allelic copy number loss also coincided with reduced expression of USP15 and SCAF1 and patients with deep or shallow USP15 or SCAF1 deletions showed a significant trend towards a shorter overall survival (Fig. 6b and Supplementary Fig. 8a ).

6c ), demonstrating a pronounced trend towards lower scores for ZF targets, suggesting fewer unfavorable interactions (Supplementary Fig. 4 , 5 ).

Among the 2465 CHIP variable-protein pairs being compared (493 proteins × 5 CHIP variables [ DNMT3A, TET2, ASXL1, JAK2 , and composite CHIP]), 30.8% was nominally significant in at least one of the SomaScan-based and Olink-based results.

The electrochemical impedance spectroscopy (EIS) of 50 μm Li||Ni92 cells at different state of charges (SOCs) shows that the cell with the GMFN shows a decreasing trend of impedance from the 1 st to 10 th cycle (Supplementary Fig. 35 ).

A statistical trend for an association with mood was further detected for the AAA ( t = 2.6, p uncorrected = 0.011, p corrected = 0.061, subpart 9, light green on Fig. 2A ) and the intercalated nuclei ( t = 2.46, p uncorrected = 0.016, p corrected = 0.089, subpart 10, green on Fig. 2A ) (Fig. 2L, M , Supplementary Table S4.d ).

Accordingly, we subdivided the compiled Ordovician Δ 199 Hg profile into four intervals, including (1) a decreasing trend of Δ 199 Hg values during the early Tremadocian to middle Floian (~485-473 Ma), (2) a dominance of near-zero Δ 199 Hg values during the late Floian, followed by a decreasing trend from positive to near-zero values during the earliest to early Dapingian (i.e., the LFCE) (~473-468 Ma), (3) a gradual

Globally, wind-solar supply systems have experienced an increasing trend in extreme long-duration events, although there are repeated up and down undulations irrespective of their frequency, duration, and intensity.

For the z-SDMs of Al-Al pairs, there is an obvious trend to be close to the signature of D0 3 -CSRO except zone 1.

In the present study, we found an overall trend of relaxed selection amongst human-infecting compared to bird-infecting trichomonad species, suggesting higher levels of genetic drift as a factor in their genome expansion.

At the pre-NAT time point, ctDNA-positive patients showed a trend towards inferior RFS compared to those who tested ctDNA-negative.

Plant height also showed a similar pattern, but the interaction soil lines x soil was only marginally significant (Supplementary Table 6 and Supplementary Data 1 ).

8a ), it is evident that H C , R xy , and T C exhibit a decreasing trend at varying polarization voltages as temperature increases.

The OH − mobility ratio in ISG compared to liquid-phase electrolytes exhibits an increasing trend, peaking at approximately 25 with 40% of ISG content.

As satellite retrievals and reanalysis products indicate a positive trend in Q v near the surface over the last four decades 41 , the connection between water vapor and σ W explains some of the positive trends depicted in Fig. 1 .

However, the D208N mutant showed a clear trend towards hexamer formation even before incubation, with the hexamer fraction becoming dominant at equilibrium (Fig. 2f , middle).

Although the difference was not statistically significant, a clear trend towards an increased expression pattern was observed in the CIP group compared with the CTL group (Supplementary Fig. 3d , e ).

Notably, the EI transcriptomes did not change drastically at 19 d, and after 22 d, the EI transcriptome showed a trend toward aging, but was considerably milder than the aging state of the UT group (Fig. 2d ).