Excerpts

Our analyses unravel an overall trend of tropic dry season lengthening and identifying some hotspot regions of changes.

Our plots on systemic circulation lifetime in mouse versus nanoparticle elasticity reveal a non-monotonic relationship, rather than a monotonic one as claimed by prior reports (Supplementary Table 1 ), though plots of normalized cellular uptake versus nanoparticle elasticity lack a clear trend as did in prior reports (Supplementary Table 2 ).

Such savings are highly significant, particularly for design optimization applications where a huge number of forward predictions are often necessary.

We detected a clear trend: the Ki67, LDHA, and MCT4 levels were increased from grade II to grade III and gained to grade IV (Fig. 2b ), and there was a positive correlation between the levels of above LA metabolic indicators and the extent of glioma proliferation (Supplementary Fig. 1 ).

In the two rescue cell lines (KO WT and KO Q107A ), there was a slight trend in the upregulation of the expression of the Rab3B and Rab34, which was only significant in the case of Rab3B for the rescue with the WT construct (Fig. 8b ).

The weakening of differential loops during MO differentiation also showed a trend towards higher signals of RAD21 peaks in MO within corresponding anchors (summarized in Fig. 4d ).

While the effects of CTCF knockdown were moderate, they were clearly significant.

It is evident that there is a weak trend of increasing the energy with smaller device area, with μBLASTs exceeding 1 fJ/μm 2 in energy dissipation, but the results still indicate that device scaling still greatly benefits the devices.

The 2nd choice omission error rate in 2 steps condition showed an increasing trend in the CNO condition as compared to saline control (Fig. 4a ).

There was a clear trend showing the inhibition of H 2 production at 104 °C, coinciding with the enhanced production of H 2 O 2 (Figs. 3 , 4 ; Supplementary Fig. 8 ).

Ana showed a trend towards increased food intake, weight, and fat mass in the female mice (Fig. 5f–h ).

In 2017, a genome-wide association study (GWAS) performed on 10,784 ccRCC patients and 20,406 controls identified one highly significant risk locus (rs4903064) in DPF3 and, more importantly, found that the risk allele was associated with increased DPF3 expression in two independent ccRCC cohorts 22 , 23 .

Here we show a significant trend towards earlier onset of tropical cyclone activity in the North Atlantic basin, with threshold dates of the first three percentiles of accumulated cyclone energy shifting earlier at a rate exceeding five days decade −1 since 1979, even correcting for biases in climatology due to increased detection of short-lived storms.

IHC score showed a positive trend with CD73 mRNA expression in all HGG cases with bulk sequencing from the larger CBTTC cohort ( n = 39), though this did not reach statistical significance ( p = 0.052; n = 39) (Fig.

EMF-associated plants showed an increasing trend of AGB, BGB, and R/S under warming (Fig. 5 ), likely due to hyphal-facilitated soil organic matter (SOM) degradation and root nutrient absorption 47 .

and an increasing trend from 1850 C.E. onwards, suggesting a temperature effect on stalagmite Mg/Ca, with high Mg/Ca corresponding to high temperature.

Precipitation reached a second peak in the late 1700 s, followed by a decreasing trend until the end of the LIA.

10c ), we did not see a clear trend in the change in the bulk composition of the annealed samples (Supplementary Fig. 8 ), which again suggests that the introduction of defects can occur more easily on the surface than in the bulk of the NCs.

The resulting Kendall τ coefficient ranges between −1 and 1: where values close to 1 indicate an increasing trend, and −1 a decreasing trend.

To measure the strength of the trends in the indicators for each period, we use the Kendall’s τ correlation coefficient, in which positive values indicate an increasing trend, interpreted as declining resilience 29 .

S r1 shows a decreasing trend with the increase of temperature, while the changes of S max1 − S r1 and S max2 are almost the same, indicating that the high residual strain comes from the non-180° switching and stabilization of the domain, while the reversible strain can be achieved by applying a cyclic electric field.

We also find clear evidence in support of the role of light environment in promoting the evolution of ultraviolet plumage colouration, and a weak trend towards higher ultraviolet plumage reflectance among bird species with ultraviolet rather than violet-sensitive visual systems.

Here, an increasing trend in the LMW DOC signifies a shift to carbon with lower molecular weight and higher bacterial productivity 24 , 69 while increasing C/N ratio may indicate increasing biodegradability of DOC 70 .

The relevance of these variables for explaining changes in mollusk species composition is demonstrated by the highly significant correlations between site scores on the first two PCoA axes (using the entire variance of the species data) (Supplementary Fig. 1 , Supplementary Table 3 ) and the CCA (using only the variance explained by the given factors) (Fig. 2 , Supplementary Table 2 ).

Cluster 1 represents Msx1 + Acan + cells and cluster 2 represents Msx1 + Col6a5 + cells, and cluster 2 showed a trend toward cluster 3 (Supplementary Fig. 11g–j ).