Barely Significant

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Although the results were marginally significant, there exists a potential association with LMM, suggesting that the nutritional imbalance resulting from a diet characterized by a reduced intake of protein-based foods, alongside increased consumption of refined carbohydrates, high glycemic index foods, and saturated fats, may contribute to the decline in muscle health.
After a 12-week intervention, compared with the placebo group, the probiotic group showed a significant increase in muscle mass and fat free mass ( p < 0.05), a significant decrease in fat mass ( p < 0.05) and a decreasing trend in body weight; however, the difference was not statistically significant ( p = 0.07).
The highest quintile of GPC intake was associated with a significant reduced risk of cognitive decline (HR: 0.468, 95% CI: 0.283, 0.771), and a significant trend ( p -trend = 0.0448) across quintiles of dietary GPC intake was observed in Model 1 ( Figure 3 ).