Barely Significant

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a decreasing trendp < 0.0010.0× alphagold
There was a statistically significant increasing trend of total energy ( p for trend < 0.001), and percent of energy from carbohydrates ( p for trend < 0.001), and total sugar intake ( p for trend < 0.001) moving from non-consumers up through the highest level of intake, while there was a decreasing trend in percent energy from total fat and protein ( p < 0.001, Table 3 ).
highly significantp < 0.0010.0× alphaqualifiedgold
Bartlett’s test of sphericity was highly significant (χ 2 = 2349.67, df = 231, p < 0.001), confirming that the correlation matrix was not an identity matrix and that the variables were sufficiently interrelated for factor extraction.
a decreasing trendp < 0.0010.0× alphagold
The serum-UA levels of mice in different treatment groups showed a decreasing trend after gavage administration, among which the positive control group and the HPO group showed excellent UA-lowering efficacy (*** p < 0.001); no statistically significant difference was observed in the comparison between the groups ( Figure 5 A).
highly significantp = 0.0010.0× alphaqualifiedgold
However, pairwise comparisons showed that this overall difference was driven primarily by the dietary contrast, as all ND-versus-HFD-based comparisons were highly significant (R 2 = 0.281–0.404, p = 0.001), whereas the high-dose probiotic group did not differ significantly from the HFD control group (HFD vs.