hMSH6 SNP rs1042821 showed a significant trend (P trend <0.001) associating younger age at diagnosis (<50) in breast cancer cases in North Carolina [ 78 ]. hMSH6 Pro92Pro polymorphism (rs1800932) showed a protective effect for tumors in the colorectum and colon in patients with Swedish origin (n = 1103 for colon cancer, n = 637 for rectal cancer, and n = 436 for controls) with the rare allele being associated with increased levels of mRNA and ovarian aging [ 79 , 80 ].
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Because the number of bits in a PMV is proportional to the number of patterns, the memory requirements for storing the PMVs might be significant.
an overall trendgold
While an overall trend of a one-to-two order decrease in magnitude in biofilm biovolume was observed in the high millimolar range, at the low millimolar range, there was a concentration that supported a modest increase in biofilm biovolume.
The biases for all NHP were smaller and less likely to be significant when reaching for the target.
The demographic history of the segment B of the IBDV genome for non-vvIBDV lineage, showed a trend toward a decrease in genetic diversity, possibly generated by the introduction of effective vaccination programs against classical and low virulent strains from early stages of the discovery of the disease [ 67 , 68 ].
Although these variants also resulted to be nominally significant when analysing the other chips, they lost their significance after adjusting for multiple testing (see Table 3 ).
The mean 1HPG values showed a decreasing trend in both treatment groups.
Acute phase protein gene expression of Saa1 showed a trend toward upregulation.
Negative and slightly significant interactions, DPI*NDA and DPI*BOR, were also noticed.
a clear trendgold
abundance show a clear trend.
Moreover, an actual decrease in sympathetic activity would have resulted in a decrease in HR, whereas an increasing trend was observed.
Mean costs per patient for antimicrobial medication ( C ab ) showed a trend towards decreasing costs compared to the historic control groups, however it was not significant.
Therefore, our study showed a trend to an association of the variant haplotype with the ring sideroblasts.
However, the importance of the Arg209 in the OmpR structure is quite significant since it may establish interactions with other amino acids that may be critical to activate gene transcription.
The difference between CPT1 (before hypnosis) and CPT3 was statistically significant in the control group and almost significant with moderate effect size in ADHD group.
Blood flow Although fitting to all the variants B1–B4 confirmed highly significant dependencies on their respective variables, B3 and B4 were unable adequately to explain the data variance ( R 2 = 0.75 and R 2 = 0.52, respectively), consistent with our analysis of the model structure.
This is the first study reporting a significant trend in TF and patient survival improvement throughout the vintages in a developing country and after adjusting for multiple covariates.
Co-inertia analysis showed the relationships between microbial community composition and environment factors were marginally significant and significant for 20 groundwater and 19 sediment samples, respectively (groundwater: p = 0.07, r = 0.351; p = 0.002, r = 0.507).
Given these strong correlations and highly significant p-values, we interpret these results as strong evidence of a global tendency to constant average length (the equilibrium position) that constrains the effects of the local evolutionary pressures that are visible in the fine structure.
In CAL there was a marginally significant decrease of 0.036 mmol/L [-0.072, 0.001].
Learning interaction A group (AN, HC) by event ( F-Corr , S-Corr ) interaction revealed that the AN group had increasing activation in the right posterior cingulate cortex from F-Corr to S-Corr whereas the HC group exhibited a decreasing trend.
Oppositely, AN show decreasing activation in the right precuneus from F-Corr to S-Corr whilst HC exhibited an increasing trend ( Fig 3A ).
Along with the fermentation process, both sets showed an increasing trend in pH because the acids were rapidly consumed by methanogens, thus increased the pH and stabilized the digester performance [ 21 ].
VFAs in PM 1 and PM 2 had a decreasing trend in the process of fermentation, which is consistent with the theory of anaerobic fermentation that VFAs were oxidized into substrates slowly by methanogenic bacteria [ 26 ].
a negative trendgold
For the north of the Gurbantunggut Desert, the contours of the >63 μm particle content ( Fig 8A ) present a negative trend with increasing distance away from the Gurbantunggut Desert, with the content ranging from 90% to 30%.