Excerpts

As well as progressive atrophy, we noted that atrophy first became measurable in the thalamus during the period of study and hippocampal volume showed a trend towards a significant volume change, although this did not survive correction for multiple comparisons.

In our investigation, the average ratio of maternal age less than 20 years was 0.9%; this ratio showed an increasing trend and reached the highest point (1.7%) in 2011.

The incidence of chromosomal aberrations exhibited a decreasing trend, which was probably related to the introduction of advanced noninvasive prenatal diagnostic methodology with subsequent induced abortion [ 37 ].

12 as inferred regulator(s) and 20 QTL in three major downstream groups, supported by 60 highly significant pairwise interactions ( S7 Table ).

The association with chronic bronchitis was borderline significant.

These data may explain why women with ER-negative and PgR-positive disease in the EBCTCG meta-analysis showed a trend towards initial benefit from adjuvant tamoxifen, an observation which was lost with longer follow-up.

The study gives support to findings of a previous study which propose a change in Mn content of plants as a potential cause of breakage of many antlers in Spain: an effect of climate reduced work to peak force in antlers by 10%, impact energy by 27%, cortical thickness by 30%, and also affected content in ash, Ca, P, Mn, Si, Na, Co, Cu (in this case only with marginal significance), and Fe.

The HER2 + /PIK3CA wt cell line, EFM192A, did show synergy with GSK2141795 and also displayed borderline significance with lapatinib plus GSK690693.

There were no statistically significant differences in hit rate, false alarm rate, sensitivity index or response bias between the two groups although response bias approached significance.

ICW/H 2 and ECW/H 2 exhibited an increasing trend in accordance with the TBW/H 2 quartile.

Among these risk factors, a clear trend of increased risk was observed for alcohol consumption and smoking (linear trend test P <0.0001 for both variables).

Salt preference and alcohol consumption had were marginally significant (< 0.1; these variables were thus included in the model), and meal regularity and physical activity had no effect on gastric cancer incidence in women.

Similar results were found for men, and only meal regularity had marginal significance.

In Romania, the overall incidence of tuberculosis was approximately 100 cases per 100,000 population in 2011, with a decreasing trend from an incidence of 142 per 100,000 population in 2002, but the number of severe cases of TB in children (meningoencephalitis, miliary, cavitary) still maintains a high annual rate (65/100,000 in 2011) [ 4 ].

Health outcomes demonstrate a positive trend for all groups between 1999 and 2010 (Tables 6 and 8 , Fig 2e–2g ).

All but one of the 13 respondents who perceived a negative trend in manatee numbers blamed it on hunting pressure (6 respondents) and/or reduced water level (7 respondents).

The relationship between ΣPCBs in resting females compared to pregnant (p = 0.065) and lactating (p = 0.066) females was almost significant, having controlled for other factors.

If we first focus on the examples for market parameters in the bistable regime (first column, a = 5 · 10 −4 , h 0 = 10 −3 ), we find a highly significant autocorrelation of absolute returns which only falls off slowly, in accordance with previous empirical literature [ 2 , 4 , 58 , 59 ].

ively at interventions delivered in the late phase of stroke recovery; one finding no benefit,[ 17 ] and the other (based on a single study) finding strong evidence of benefit.[ 21 ] Two reviews reported measures of community reintegration,[ 22 , 23 ] both of reasonable quality, and both identified a significant trend favouring therapy intervention.

Several studies provide increasing evidence that such variable Aβ peptides may be significant in AD pathogenesis [ 6 – 9 ].

In species collected from sufficiently large geographic areas, the intraspecific variation was non-randomly distributed and showed highly significant negative correlation with latitude (in 2x A . alpinum and 4x A . odoratum ) and a less pronounced but still significant association with altitude (positive in 2x A . alpinum and negative both in the “Mediterranean diploid” and 4x A . odoratum ) ( Table 2 , S1 Fig ).

Between-group statistical differences were assessed using unpaired t -tests, with p < 0.05 used to define a significant difference and p < 0.0001 used to define a highly significant difference.

A clear trend was only seen in the postmenopausal group and in those who were nonsmokers (overall trend p-values of 0.004 and 0.023 respectively).

In the first case (>45% recovery) statistical analysis showed a trend towards lower values of total cholesterol (p 0,0584) in patients showing recovery.

In addition, the mutational site of 1896 was identified for its association with survival at a borderline significance level.