Excerpts

Patients who had both types of FLT3 mutations showed a trend towards worse OS compared to patients with single FLT3 -ITD mutation status (HR: 1.1, 95% CI: 0.4–3.3) ( Figure 1A ). 443 of 672 patients achieved a CR.

HEK293a-Shh cells treated with Hhat-#2 siRNA co-cultured with C3H10T1/2 cells (ratio 1∶2) for 2 days during day 2–4 of KD, resulted in a C3H10T1/2 response decrease of 32±10% compared to non-targeting siRNA, but this did not quite reach statistical significance.

For both the vocabulary learning and visual acuity performance we found a highly significant effect of the factor spacing interval on the final test performance.

The fact that borderline significance in gene overlap was also observed for categories of disorders sharing clinical risk with MDD (i.e. cardiovascular diseases, inflammation and metabolic syndrome) suggest that the same gene sets may also contribute to dysfunctions in peripheral organs through pleiotropic functions of common genes, hence providing putative biological links for the clinical and symptom co-morbidity.

However, we adjusted for this by using Bonferroni correction with many associations remaining highly significant.

Our study would not determine the potential SNP or indel variation in the SVA; such variation may be significant for both clinical association with disease and transcriptional properties of the SVA.

All paired t-tests were highly significant, except for one marginally significant outcome (after Bonferroni correction). 3.1.2 P3b component Figures 2 – 5 present grand averages for all experiments.

A p value <0.05 (marked as *) was considered statistically significant, and p<0.01 (marked as **) highly significant.

This is highly significant in terms of the cost of running high-throughput screening assays or routine assays spanning long experiment times typically associated with TSE infection in animal models.

The variability in summer biomass, which lacked a clear trend, was only explained by the BSI.

While the effect of temperature was weakly positive for the BB, it was highly significant and non-linear for the GD, with an overall negative trend.

Often, and indeed in our own case, there may be significant geographical separation between the operating room and the diagnostic laboratory.

All factors except for (female) sex had a highly significant influence on mortality in model 2.

All the values compared were found to be highly significant.

In fact, our comparisons of individual and JEM-based measures of lifting supported a decreasing trend of lifting exposures with increasing gestational age.

The regressions give marginally significant p-values for the interaction between country and gender, which remain when controlling for age and risk preferences in the analysis using Tobit but disappears when we use ordinary least squares.

Indoor cooking with the intervention stoves as opposed to the traditional stove was associated with a 37% reduction in 24-h PM 2.5 , which was of borderline significance.

Although no statistical significance was identified, the new P2Y 12 receptor inhibitor, ticagrelor, showed a trend toward achieving the greatest beneficial effect compared to other regimes, which gives it the highest probability of being the optimal therapy.

This relationship was highly significant, and the regression equation was used to estimate BM E for animals where it could not be directly calculated.

There was stable improvement in those stroke transplanted with high doses of cells (Groups C and D) which showed a trend of better improvement over time up to the 56-day study period.

During the last decade, there is an increasing trend of SST values in the eastern Mediterranean Sea [56] .

For the comparison of genetic distance with both geographical and linguistic distance, the correlation coefficients obtained within linguistic phyla were, on average, approximately 10 times lower than those obtained for the complete dataset and not or only marginally significant.

The direct economic consequences of oral mucositis induced by cancer therapies may be significant and require allocation of considerable resources [13] – [15] .

The average permutation-based P values ( Figure 7 ) in both Archaea and Eubacteria are , which show that there is a highly significant relationship between sequence-similarity and isoenzymatic weights in both domains.

Interestingly, Knowles HJ demonstrated that OS cells showed a trend toward increased hypoxic migration and responded to HIF-siRNA, with targeted inhibition of HIF-2α resulting in increased cell migration under hypoxia [35] .