Excerpts

After other variables have been taken into account, the country-level Gini ratio of household income inequality in 1989 has a highly significant power relationship with the number of threatened plant and vertebrate species in 2004 ( P = 6.4×10 −6 ).

This asymmetry is highly significant for the 24 pairings in flexor dominated bouts considered alone (average difference .0346±.0075; 20/24>0; p = 6.68×10 −6 ).

Although no gene achieved genome-wide significance in the meta-analysis (Bonferroni-corrected p < 2.4 × 10 −6 ), the meta-analysis p-value for the germ cell-specific gene, GGN , was of borderline significance (p = 7.1 × 10 −6 ).

Kaplan-Meier analysis showed a trend for significantly shorter MST with increasing number of risk alleles for the OS in patients with HBV-related HCC (Log-rank P = 7.72×10 −6 ; Figure 2 ).

The interaction between rs16847548 and sex in Whites was also highly significant (+2.00 ms, P = 8.68×10 −6 for the interaction term), whereas no sex interaction was observed for rs16856785 (P = 0.31).

Highly significant results were obtained for SORL1 SNPs rs4598682 ( P = 9.51×10 −6 ), rs3781834 ( P = 7.33×10 −7 ), rs17125523 ( P = 5.51×10 −6 ), and rs3737529 ( P = 4.14×10 −6 ) after combining results from the discovery and replication samples ( Table S3 ).

As shown in Figure 9A , EBNA2-wt activated the promoter by about 500-fold (p = 0.0000000016), while the activation by EBNA2-ΔRG was lower but still highly significant (p = 0.000009975). hnRNP K-wt or the 5RG-mutant alone exerted a small but significant activation on the promoter construct (p = 0.000173 and p = 0.00529, respectively), while co-expression of hnRNP K-wt enhanced the EBNA2-wt-mediated activation by up to three-fold (p = 0.001675).

In line with these observations, the 2 (task: judge number/mean size) x 2 (unattended magnitude: small/big) repeated measure ANOVA performed on PSEs estimates showed a highly significant interaction between task and magnitude of the unattended dimension (F(1,13) = 52.17, p<10 −5 ), with PSE estimates differing between small and large unattended magnitude only for the average size task (p<10 −5 ) but not for the numerosity task (p = 0.37).

A highly significant difference in the post-surgical AP dimension was found favoring two-jaw over one-jaw surgeries ( p <0.00001) in OP airways; MD = 3.04mm [95%CI2.76, 3.32], I 2 = 48%. 3.

T-test statistically confirmed the highly significant response of M2e ELISA test to live virus infection at p = 0.00001(data not shown).

Both values are very large and highly significant (p<0.00001) compared to chance levels (1/49 or about 2%, dashed line, which corresponds to the average, 49.2 (SD 2.3) cards presented in each riffle, which is slightly less than the total number of cards -52).

However, after correction for multiple testing, the association did not reach statistical significance (an interaction term P -value <0.00001 was considered statistically significant after correction for the number of interactions tested [23×23 = 529; 0.05/529 = 9.5 10 −5 ].

The increase in PNN density (normalised to the cross-sectional area of the neostriatum) between P10 and P14 was highly significant (one-way ANOVA, Tukey-Kramer test; F(5, 48) = 142.14, P<<0.00001; Fig 7A ).

During the Conditioning phase, highly significant (p<0.00001) main group and training day effects were observed and those were sustained over the entire period of Conditioning.

The frequencies of white choices in S1 and S2 showed a highly significant difference between sessions (χ 2 = 272.23, P <0.00001).

We tested the five significant or marginally significant SNPs (p < 10 −5 ) using standard linear regression models adjusted for the same covariates as above ( S1 Table ).

For example, witnessing violence toward siblings on the MACE showed a highly significant association with DES scores (β = 2.02, t = 4.75 p < 10 -5 ), whereas witnessing interparental violence did not (β = 0.60, t = 1.44, p = 0.15) and experiencing physical abuse had only a marginal association (β = 0.85, t = 1.83, p < 0.07).

This superiority of RBZ and RBZ + Laser compared to laser treatment in terms of a positive effect on BCVA were highly significant (WMD = 5.65, 95% CI, 4.44–6.87, P<0.00001 and WMD = 5.02, 95% CI, 3.83–6.20, P<0.00001, respectively), with no heterogeneity identified ( Fig. 2A and 2B ).

For the third most significant genotyped loci, located on chromosome 8 in the vicinity of the ZNF704 gene, borderline significance was achieved ( P <10 −5 ).

The identification of moderately significant (10 −2 >p>10 −5 ) SNPs offers a novel method for detecting the “missing heritability” of hypertension.

However, the Bray-Curtis dissimilarity between the two data is highly significant, using the two-sided t -test with p-value <10 −5 .

However, several nominally significant (p<1.00E-05) variants were identified ( Table 2 ).

While performance was similar among groups under nonaugmented feedback conditions [ F (2, 24) = 0.048; p = 0.95], a highly significant Group effect was obtained in the presence of augmented feedback [ F (2, 24) = 51.84; p ≤0.00001].

The increments in luciferase activity produced by the addition of increasing amounts of human rMCP-1 to antigen stimulated cells were significant for the allele 1G (ANOVA F = 10.23, p = 0.005) and highly significant for the allele 2G (ANOVA F = 172.3, p <0.00001).

In particular, the differences are highly significant on branch #1 and branch #2 during the genome reduction period (Student's t-test, P- value<10 −5 ).