Barely Significant

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highly significantp value < 0.051.0× alphaqualifiedgold
Ingenuity Pathway Analysis (IPA) Enriched canonical pathways in CD105+ cells as revealed by IPA analysis IPA of common differentially expressed genes from CD105+ cells isolated from primary and metastatic RCC revealed highly significant overlap of a total of 335 canonical pathways with p value < 0.05.
borderline significantp = 0.051.0× alphagold
Intermittent opioid use appeared to be associated with decreased memory CD8+ T cells proportion (CD45RO+CD45RA- CD8+ T cells: adjusted mean difference [AMD] [95% CI] = -6.15 [-11.50, -0.79], p = 0.02) and borderline significant increased senescent T cells (%CD57+ of total CD28-CD8+ T cells (AMD [95% CI] = 7.70 [-0.06, 15.46], p = 0.05).