Excerpts

Discussion In a population with chronic mental illness, various SNPs in 10 candidate genes ( PPP1R1B , BDNF , DRD3 , DRD2 , HTR2A , HTR2C , COMT , MnSOD , CYP1A2 , and RGS2 ) reached nominally significant (p≤0.05) associations with drug-induced movement disorder.

We found many bacterial species that exhibited highly significant correlations to these traits ( Fig 5A–5C , 967, 720, 1,056 bacteria out of the top 1,345 occurring bacteria had significant Spearman correlation, P-value < 0.05 after FDR correction for age, HbA1C% and BMI respectively, S12–S17 Tables in S2 File ).

S6 Dataset A list of 497 genes that showed marginally significant difference in viral induced gene expression changes between asthmatic between non-asthmatic ALI samples (nominal p <0.05).

By fitting a linear mixed-effects model, we identified a total of 497 genes with nominally significant difference (p< 0.05) in viral infection response between asthmatic and non-asthmatic groups ( S6 Dataset ).

Pearson correlation coefficients revealed a modest and marginally significant correlation between total BACS and total SSTICS scores for the non-clinical comparison group (r = −.31, p = .05, n = 41) but no correlation for the patients (r = −.05, p = .62, n = 117).

Among the regions considered, only the right TPJ (associated with mentalizing on action goals) showed a trend towards significant activation (p<0.05 uncorrected) while observing both cooperative and affective pictures.

Indeed there was a significant main effect of shock (F (1,24) = 6.40, p<0.05) but the lesion×shock interaction fell short of significance (F (1,24) = 2.07, p>0.05).

Results Immune Priming and Serratia Marcescens Infections For Experiment 1 ( Figure 1A, B ), the minimal model indicated a marginally non-significant interaction between aphid genotype, pre-exposure, and infection treatment upon second challenge (p = 0.05), which is reflected by the somewhat different responses of the two aphid genotypes (5A0, LSR1) to pre-exposure and subsequent live bacterial challenge ( Figure 1A,B ).

The estimated yearly decrease in trachoma in the control communities was -·04%, compared with -0·9% in the intervention communities, and this difference in the rate of change between control and intervention communities was borderline significant (p = 0·05).

Moreover the test for the interaction between the linear trends failed to reach significance [F(1,26) = 3.94, p < 0.05].

Based on a quantitative real time PCR analysis, it appears that rodents subjected to TNI exhibited substantial increases in NaV1.7 mRNA by day 28 compared to naïve tissue levels, whereas post-injury day 14 values did not reach statistical significance ( Fig. 6 ; n = 4, ANOVA, F = 5.571; p<0.05).

Nominally significant association (P<0.05) was observed for markers in: TCF7L2, RBMS1, CDKAL1, ZNF239, KCNQ1 and TCF1 and a significant bias (P<0.05) towards OR>1 was observed for markers selected from previous T2D genome-wide association studies, consistent with a role for Old World variants in susceptibility to T2D in Latin Americans.

The statistical interaction between dose and density was marginally significant for day of death ( H = 7.813, df = 3, p = 0.05; Figure 1B ) with tadpoles exposed to Dose 3 dying significantly earlier in low density tanks but not when held in high density conditions ( Figure 1B , Table S1 ). 3.

The main effect of identity strength was marginally significant [ F (4.467,31.266) = 3.651 P <0.05].

The interaction of block and training type was marginally significant, F (3.18, 248.30) = 2.59, p = .05, η p 2 = .032, as accuracy increased more across blocks in the Response conditions than in the Observation conditions.

The difference was significant for five genes ( CD63 , RHOB , LOC399491 , ZNF24 , ANAPC5 ) and close to significance for an additional six (p = 0.05–0.09) ( MAN2A1 , CASP4 , SUPT4H1 , VCP , PARP1 , SSRP1 ) by means of t-tests.

The interaction between type of stimulus and form of script was marginally significant ( F (1,31) = 4.08, p≤ .05, η p 2 = .12). t -tests suggested significantly longer reaction times in response to the pointed script only in reading of words ( t (31) = 3.29, p <.01).

Expression increases in miR-186 from post- to 60 min post-exercise (fold change = 1.58, P <0.001) paralleled a significant upregulation of SIRT6 mRNA (fold change = 1.66, P <0.05), a significant downregulation of TERF2IP mRNA (fold change = 0.54, P <0.01) and a strong trend towards significance for RAD50 (fold change = 0.76, P = 0.05).

The downregulation of miR-181b expression between post- and 60 min post-exercise showed marginal significance (fold change = 0.84, P = 0.05) and paralleled significant upregulation of potential target TERT transcript (fold change = 14.75, P <0.05).

• In GSEA, looks like the authors used both significant and weakly significant (p-value > 0.05) genes.

A nominally significant association was observed between survival and the DPP4 enzymatic activity at day 1 (p<0.05), with a higher DPP4 activity being associated with an increase in survival.

This effect was nominally significant (p < 0.05) for four of the eight fingers tested: left 2 nd finger, left 5 th finger, right 2 nd finger, and right 4 th finger ( Table 2 ).

Although marginally non-significant (p-value = 0.050, df = 4), the G-test results showed a tendency for gomphid larvae to display a natural post-mortem position, with the hind legs extended laterally and the forelegs extended close to the body.

Finally, the Proteobacteria showed a trend of increasing with age: the relative abundance of Proteobacteria in the 100-day-old group was significantly higher than that in the 80-day-old group (P<0.05).

In fact, in most cases, the MRI-only and PET-only models predicted MCI conversion with above-chance accuracy levels (65–70%), and this performance approached significance but simply failed to exceed the accepted p <0.05 cutoff.