Excerpts

[3] Another small randomized controlled trial studying the effect of diclofenac/misoprostol in AD, found a nonsignificant trend of more advanced deterioration in the placebo group than in the diclofenac/misoprostol group.

The difference between the two groups remained highly significant even when this outlier value was excluded.

Medium effect For all traits, the medium effect was highly significant ( Table 2 and Figure 1 ), and accounted for the most important part of total variation (from ∼34% for J T 50 up to ∼80% for S ).

Although only marginally significant, this result is in line with the prediction that these genes are members of a co-adapted gene complex and illustrates that searching for main effects alone will could miss relevant determinants of complex phenotypes, although a replication of this association in an independent cohort would be needed before any conclusions can be drawn.

In the two Asian groups, the TRPV6 locus had a significant proportion of SNPs that were above the 95 th percentile of their respective Rab bins, while Europeans were nearly significant.

[24] , who showed a trend of more-self-likeness (measured in terms of number of shared amino acids) among HIV peptides with no detectable CTL responses in a large study group.

In plasma the difference between the two groups was nearly significant for δ 13 C ( Table 1B ).

A single icv infusion of LipoDoxycycline or LipoMinocycline at the onset of the first neurological symptoms increased survival, reaching statistical significance for doxycycline and close to significance for minocycline.

In females, the MDM2 SNP309 locus and the age of tumor diagnosis share significant mutual information whereas, in males, the level of mutual information measured did not quite reach significance ( Figure 2 ).

Assumptions of independence are violated in AIL populations, and non-syntenic association can cause occurrence of nominally significant results to be more frequent than expected.

For asymptomatic phenotypes, prevalence (PtPF) gave lower LOD scores than parasite density (mean or maximum), although it showed highly significant heritability in Ndiop.

The correlation coefficient for consecutive turning directions, for all cells, was −0.36, with a P-value<10 −4 , a highly significant anti-correlation.

Remarkably, after 106 treatment gene expression profiles showed a clear trend toward normalization.

The distribution of the serious adverse events was not significantly different in the two treatment groups, except that an increased incidence of abdominal pain with AL was of borderline significance.

Based on qPCR analysis, ANOVA showed highly significant differences between diagnoses for the entire model and in many cases also for individual genes.

A positive trend between the specific IgG level and the intensity of exposure was found for gSG6-P1 and for gSG6-P2 in this subsample and this association was only significant for gSG6-P1 (P<0.05).

A Cochran-Armitage trend analyses [27] was used to confirm that a significant trend in survival probabilities existed among vaccinated and unboosted, and vaccinated and boosted groups relative to naïve mice in vaccination/challenge studies ( Table 2 ).

The decay of mutant mRNAs compared to wild-types was significant for MSH6 ( P = 0.02; Student's t-test) and nearly significant for a few others only, e.g.

In the first experiment, tadpoles with resistant haplotypes ( f and j ), but not those with a susceptible haplotype ( g ), showed a trend of reduced growth when exposed to the pathogen, which suggests a possible tradeoff between growth and immune function.

On the contrary, our data showed a significant trend for mutation to lead to a decrease in allele size recorded in 11 out of 15 observed cases.

Note that an improvement of classification accuracy by bias adaptation was highly significant for two subjects.

These dynamic changes implied that the phosphorylation of TCTP from 2.5 hr to 4 hr might be significant to guarantee this process running smoothly.

The structural equation model revealed a highly significant association between the genotype and LDL-C as well as between LDL-C and CAD risk, but the association between rs2228671 and the risk of CAD was abolished (OR 0.99, 95 % CI [0.85–1.16], p = 0.95, Fig. 5 ).

all the genes that are reported in a particular list, the P-value associated with the number of genes contained in this list will likely be highly significant according to how unlikely it is to obtain all the genes contained in a given list in a random draw from all genes present in the bipartite graph.

The largest difference was a 38% increase in perceived albedo and differences are both highly significant and patterned.