Excerpts

Using GLMMs, we accounted for some of the correlation structure of GPS animal tracking data; however, parameter standard errors remained very small and all predictors were highly significant.

Further comparisons between these two regions indicated a significant, or nearly significant difference in species diversities, depending on which diversity measures were used (DB- or TM-based) (Fig. 4de).

Results were considered statistically significant, highly significant or very highly significant if the p-value fell below 0.05, 0.01 and 0.001, respectively.

An increasing trend in all serious complications was observed during early implementation, whereas a significant decrease occurs in the later period (p<.001).

A clear trend of narrowing down of host range with plummeting genome size was proven among the sequenced Bordetella genomes [8] .

The co-regulatory network does not see much of an increase in AUC value (0.548 to 0.590); however, this improvement is still highly significant (3.7×10 −14 ) given the size of the network that we are evaluating and the standard we are using.

Terminal cytochrome d ubiquinol oxidases, which are active at low levels of O 2 [32] , showed no clear trend with depth and the variations among layers were barely significant.

GO analysis of the Leydig enriched transcripts (7-fold or higher) revealed highly significant molecular function and biological process categories related to steroidogenesis ( Table S5 ), such as lipid, alcohol, cellular ketone and organic acid metabolic processes, oxidoreductase activity, steroid dehydrogenase activity and steroid and coenzyme binding, confirming the highly specialized nature of this cell type in the testis.

Data were then finally reviewed, and any datapoints with borderline significance that were based on population frequencies <0.25% were removed.

There were two other probes for APP (ILMN_1653283 and ILMN_2404065), both of which showed significant positive correlations in the cerebellum and temporal cortex, except ILMN_2404065, which was not significant (p = 0.21) but had a positive trend in the temporal cortex (β = 0.04).

We tested all nominally significant SNPs out of the discovery analysis in 2 replication samples, resulting in a total sample size of 894 patients.

In opposition to findings reported here, Schittone [34] documented a significant trend for the larvae of S. siderea to settle on concrete at a restoration site in the Florida Keys; however, its congener, S. radians , notably settled solely on natural substrata.

Lower, but still highly significant relations were also found with CML (a non-fluorescent AGE) and CEL [10] .

All KD-fed mice showed a trend of elevated blood ketones throughout the study; however, only KD+HBO 2 T mice had significantly higher ketones than controls on day 7 ( Figure 3 ).

Animals receiving the KD alone or in combination with HBO 2 T demonstrated a notable trend of slower tumor growth over time.

Notably, the average scores showed a trend related to age with higher scores obtained by those of older age.

The treatment effect remains highly significant.

The statistical significance of the P-value was defined as: P>0.05 - not significant, P = 0.01–0.05 - significant (*), P = 0.001–0.01 - very significant (**), P<0.001 - extremely significant (***).

Also, a highly significant reduction in DAT availability of the right caudate-putamen was noted in lesioned mice, compared to controls (p-value peak maximum = 1.9 10 −6 , T = 11.17; K ext = 1189).

Although we observed an increasing trend, iron chelators didn’t induce significant cell apoptosis after 24 h or 48 h stimulation.

However, these two genes were further shown to be associated with high levels of specific cytokines, with a dramatic and highly significant elevation compared to normal controls.

This implies that biological networks have a higher tendency to possess sparse structure or weakly significant cohesive modules, which is consistent with previous findings [23] – [25] .

A reduction was also observed for the Sciara SXL protein (SXS) when the amino (chimera SX35) (t-test: P value = 2,316; 0,05<P<0,1) or carboxyl (chimera SX28) (t-test: P value = 11,326; P<0,001) terminal domains were replaced by the corresponding Drosophila domains, with a highly significant binding reduction for SX28.

Differences were more striking with regard to poking into the hole containing a familiar versus a novel odorant where the CON+SAL and Nf1 OPG+LDOPA mice displayed a highly significant preference for the familiar odorant-containing hole while the Nf1 OPG+SAL mice again showed no significant preference.

The Nf1 OPG+LDOPA mice showed a strong trend toward increased rearing to investigate the ball versus the empty area, although this comparison failed to achieve statistical significance (p = 0.064).