Barely Significant

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marginal significanceP = 0.0320.6× alphagold
On the multivariate analysis, the G12D/V mutation was associated with a poor prognosis in both cohorts, with marginal significance (HR = 2.015, 95% CI = 1.064–3.817, P = 0.032 in the discovery cohort; HR = 2.366, 95% CI = 1.109–5.046, P = 0.026 in the validation cohort).
a statistical trendP = 0.0330.7× alphagold
However, when analysing differences due to the experimental treatments by sampling day, although no differences were found during the suckling period, a statistical trend for an increased beta-diversity in the control piglets was found after weaning ( P = 0.033, P = 0.053 and P = 0.058, for Envfit, Anosim and Adonis tests, respectively).
a positive trendP = 0.0340.7× alphagold
For the correlation between the cluster of voxelwise interaction and cognitive tests, although the results failed to survive from the criteria of Bonferroni correction, a positive trend between DSB score and putaminal volume was observed in the participants carrying AA (r = 0.189, P = 0.034).
marginally significantp = 0.0340.7× alphagold
Matched samples comparisons There were marginally significant differences in RSFC parameters (Table 2 ) for within-network RSFC of the fronto-parietal network (FPN, p = 0.034) and the ratio of within- to inter-network RSFC of the visual network ( p = 0.044; Fig. 2 ) between PRESENT shift workers and MATCHED controls.