Excerpts

Geeglm revealed that the negative effect of mother deprivation on the number of successfully reared embryos per spawning was highly significant (anova: df = 1, χ 2 = 387.7, P < 0.0001).

The analysis revealed highly significant main effects of PCA concentration (F4,40 = 550.59, P < 0.0001) and fungal species (F3,40 = 30.32, P < 0.0001).

Models generated for different quality attributes of instant phirni dry mix were highly significant ( p ≤ 0.0001).

A highly significant positive trend in hatchability was observed for the brown layer line ( P = 0.0001), with hatching rates increasing from 52% at ED4 to 87% at ED7.

The risk difference (RD) for overall dentitional anomalies in the UCL phenotype was highly significant when compared with the control group ( p ≤ 0.0001, RD = 0.36, 95% CI = 0.29,0.43).

A highly significant difference was found between the parental lines in MI ( P ≤ 0.0001), with 53.9 ± 1.97 and 70.7 ± 1.97 for IGC119 and Harari, respectively (Fig. 1 b).

As expected, LPS induced a highly significant increase of nitrites production by BV2 cells (Fig. 5 a; P < 0.0001).

The animals showed a highly significant preference (paired Wilcoxon test; V = 353, p < 0.0001, r = 0.76) for odor derived from male perioral secretions (median sniffing time: 23.17 s; SD: 26.3) over swabs from the dorsum (median sniffing time: 12.45 s; SD: 14.9), irrespective of their sex.

Viral DNA load of NS1 correlated significantly with VP1/2-DNA load (p = 0.0148; Pearson r = 0.1228; r 2 = 0.01509) and furthermore correlation of NS1- to VP1/2-RNA loads was highly significant (p ≤ 0.0001; Pearson r = 0.8817; r 2 = 0.7775).

All four models were highly significant ( p < 0.0001) with non-significant lack-of-fit tests ( p > 0.05), indicating adequate model fit.

This analysis showed a highly significant positive correlation between the two datasets for both the SLC transporters (r = 0.9157, P < 0.0001) and the ABC transporters (r = 0.8368, P < 0.0001) (Fig. 3 , Supplementary Tables S3 and S4 ), providing further confidence in our approach.

However, the difference between both normal melanocytes and skin, as well as between tumor samples and skin, was not only highly significant (adjusted p -values < 0.0001) but also substantially larger in magnitude, as shown in Fig. 2 E.

The proportion of CLas-infected (qPCR positive) leaves, following a 4-day inoculation period (with 5 insects/leaf), was 2.5% (1/40 leaves) for nymphs and 36.3% (29/80 leaves) for adults, and this difference was highly significant ( P = 0.0001 in X 2 test).

At univariate analysis MS was strongly associated with education with a significant trend (chi square 23.5; p-value 0.0003) reaching a strongest positive association for university degree (OR 6.87; 95%CI 2.90–16.20; p-value < 0.0001); MS was also positively associated with history of mononucleosis and inversely associated with history of autoimmune diseases as reported in Table 2 .

The ASR/N1 correlation was highly significant for each trial type (startle: r = 0.8, p < 0.0001; paired: r = 0.6, p = 0.01), but the correlation strength did not differ across arousal levels (Steiger’s Z: startle: Z = − 1.2, p = 0.1; paired: Z = 0.9, p = 0.2; Fig. 6 e,f).

Importantly, this relationship remained highly significant in the time-adjusted model (β = 0.000177, 95% CI: 0.000113–0.000242, F = 29.8, p < 0.0001), indicating that the structure-function correlation persists even after controlling for temporal changes during the recovery process.

Histograms indicated a highly significant increase in mean NAVs after stimulation with 2 or 10 nM iloprost ( p < 0.0001) for those phosphopeptides with PKA consensus site versus no such site (Suppl.

communis had a highly significant effect on a wide range of bacterial groups independent of the watering regime as obtained with an analysis of differential abundance (ALDEx2) ( P < 0.0001) (Supplementary Figure S2 , S3 , Table S2 ).

The difference between groups was highly significant ( p < 0.0001) (Fig. 4 a).

4 a) showed a highly significant interaction between culture medium and initial inoculum concentration ( p < 0.0001), indicating that the effect of inoculum depended on the culture medium.

500 nM Aβ 1–42 ), 23.1 ± 2.4% (mean ± SEM; n = 23) of wild type dendritic spines were associated with amyloid-β-immunoreactive puncta, whereas in contrast spines from p75 NTR ko neurons showed a colocalization ratio of only 6.9 ± 1.1% (mean ± SEM; n = 24), a difference that was statistically highly significant (p < 0.0001).

Change in bodyweight, but not epididymal fat mass, had a significant effect on xenograft mass (P = 0.0069), but the effect of treatment was still highly significant (P < 0.0001) and the differences between groups treated with vehicle, HI or IX10 were fully comparable to the effects observed when the effect of bodyweight was not included in the analysis (Supplementary Table S4 ).

The model was highly significant ( p < 0.0001), yielding the components ‘Age’, and ‘SNP.Dim.14’ as the two most important predictors.

controls, was markedly significant (respectively, 334 out of 402, or 83.1% vs . 18 out of 210, or 8.6%; p < 0001).

Our data suggest a highly significant association of MAS with PH in IUGR neonates ( p = 0.0001 ) but BA, RDS, gender, GA (weeks) and WP as a non-significant risk of PH.