Excerpts

K t and D h showed highly significant positive relationships ( R 2 = 0.87, P < 0.001), with a single slope and intercept across the three growth forms, but lianas showed a shift towards higher values for both traits ( P < 0.001).

The family health team coverage had an increasing trend from 2012 onward (APC: 3.3%, 95% CI: 0.6-6.1, P < 0.001).

The APOH transcript was more abundant in liver of Rf + embryos at e13 and e15, as indicated by a highly significant ( P ≤ 0.001) treatment x age interaction.

The KMO measure was 0.850, and Bartlett's test of sphericity was highly significant (χ 2 = 1,529.402; p < 0.001), confirming that the data structure is well-suited for factor extraction.

The overall analysis of the NSND group also showed a highly significant association with a high CPS ( p < 0.001). 3.3 Association of Immunohistochemical Expression of PD ‐ L1 , PD ‐1 and Clinicohistopathologic Characteristics The analysis of associations between PD‐L1 and PD‐1 expression with clinical parameters showed a significant association between low PD‐1 expression and advanced T‐stages (T3 + T4) ( p = 0.032), as well as the presence of lymphangiosis carcinomatosa ( p = 0.008).

The difference in mean number of symptoms named before and after the lesson was highly significant (p < 0.001), as well as the difference in percentage of participants giving a correct definition of stroke (p < 0.001) and those naming more than 4 symptoms.

Overall, the canonical axes were highly significant for both vertebrates (Monte Carlo permutation test: F (8,21) = 1.50, p < 0.001) and spermatophytes (Monte Carlo permutation test: F (8,21) = 2.04, p < 0.001).

Highly significant differences (p < 0.001) were found at the different plant growth stages, watering regime (WR) within plant growth stage, and day within WR and plant growth stage.

This association was statistically highly significant ( P -value < 0.001).

Mixed-effects model analysis of MI vs breast cancer development stage showed a significant trend for increasing levels of methylation of all four biomarkers during progression from benign towards malignant ( P <0.001 for trend by both categorical and linear mixed-effects model) ( Figure 3 ).

The coefficient for the current score difference shows a highly significant influence as well ( t = 5.10, p < 0.001), with an average increase of 0.78 s for each positive increase in the goal difference.

Tumor Subsite Tumor anatomic distribution showed a highly significant difference between NSND and SD patients ( p < 0.001).

When the six datasets were combined (n = 1334) (Figure 7K ), the positive association between Ran and VEGFR2 mRNA levels was highly significant (Pearson’s correlation 0.67, P < 0.001 ).

EtOH showed significant (*P < 0.05) at 200 mg (5.59 ± 0.29), (**P < 0.01) at 300 mg (4.47 ± 0.46), and highly significant (***P < 0.001) at 400 mg (3.34 ± 0.18) results when compared to the Diseased group (Table 4 and Fig. 8 ).

Statistical analysis revealed highly significant effects ( p < 0.001) for most factors, including sample, day, and their interactions, while proofing time alone did not show significant effects.

They quantitated the LINE-1 methylation levels of each specimen by using pyrosequencing and showed that HNSCC specimens had a marked trend toward hypomethylation compared to control samples (46.8% vs. 54.0%, p < 0.001, Mann–Whitney).

The difference in prediction of probability of overall survival (Figure 6B ) between the groups with good or poor prognosis profiles was also highly significant (p < 0.001).

The following variables that showed a highly significant statistical difference ( P <0.001) in the univariate analyses were entered a stepwise backward logistic regression model: age; Euroscore; preoperative plasma creatinine level; ScO2 minox ; type of surgery; duration of surgery; duration of cardiopulmonary bypass (CPB); lowest hematocrit during CPB; intra- and postoperative use of inotropic/vasoactive agents (noradrenaline, dobutamine, vasopressine); cumulative use of blood products; mean RPP within the first 8 hours after ICU admission, time to first extubation (hours), and reintubation.

Whereas the treatment difference was nominally significant in IFNGS-high patients (treatment difference: 18.2% (95% CI 10.5 to 25.8); nominal p<0.001), it did not reach nominal significance in IFNGS-low patients (treatment difference: 9.3% (95% CI –8.0 to 26.5) nominal p = 0.292), although the sample size of the IFNGS-low group was small (17.4% of the overall study population) ( figure 1 ; table 1 ).

Both log-rank (Mantel-Cox) and Breslow (generalized Wilcoxon) tests were highly significant ( P < .001), with the Enhanced condition showing a slower decay (less nonusage attrition) over time than the Basic condition.

However, there were highly significant differences for the susceptibility of different strains ( p < 0.001): the inhibitory diameters of P. aeruginosa strain were less than other strains, which ranged from 19.67 to 27.33 mm.

Intraoperative use of 5ALA in patients undergoing surgical resection (ie excluding patients undergoing biopsy alone) was associated with a markedly significant mOS increase from 15.9 weeks (5ALA not used) to 45.4 weeks (5ALA used, Figure 2B ), P < .001.

When assessed as a group, the difference between PBMC and MMC CD4 + T cell percentage was highly significant after 1 y (57.9% ± 11.9% CD4 + PBMCs versus 34.6% ± 4.2% CD4 + MMCs; p < 0.001), 2 y (54.4% ± 10.9% CD4 + PBMCs versus 30.8% ± 9.8% CD4 + MMCs; p < 0.001), and 3 y (67.3% ± 9.8% CD4 + PBMCs versus 41.3% ± 4.9% CD4 + MMCs; p = 0.02) of suppressive antiviral therapy ( Figure 1 D).

Five studies, 7 studies, 5 studies, 12 studies, 17 studies, 7 studies, and 2 studies were included to assess the effect of treatment on blood glucose levels at 1 week, 2 weeks, 3 weeks, 1 month, 2 months, 3 months, and 6 months, respectively, all of which showed a highly significant hypoglycemic effect in the MSC-treated group (1 week: SMD = − 1.484, 95%CI − 2.586 to − 0.381, p < 0.001; I 2 = 80.6%; 2 weeks: SMD = − 2.312, 95%CI − 3.743 to − 0.882, p = 0.002, I 2 = 89.6%; 3 weeks: SMD = − 4.007, 95%CI − 6.472 to − 1.541, p = 0.001, I 2 = 92.1%; 1 month: SMD = − 1.740, 95%CI − 2.660 to − 0.821, p < 0.001, I 2 = 83.8%; 2 months: SMD = − 1.830, 95%CI − 2.633 to − 1.028, p < 0.001; I 2 = 86.0%; 3 months: SMD = − 1.649, 95%CI − 2.838 to − 0.461, p = 0.007; I 2 = 84.6%; 6 months: SMD = − 3.045, 95%CI − 5.895 to − 0.195, p = 0.036; I 2 = 76.4%).

An increasing trend was observed in CO data until the 16th h (P < 0.001), and then CO dropped significantly below the level of the sham-operated animals at the 20th h (P < 0.001).