Excerpts

Indeed, we found that potentiation of EPSP amplitudes increased by 166.0±8.9% for rats housed in conventional cages (n = 13; t = 45−50 min after TBP, p = 0.0001) and by 227.0±14.4% for rats raised in MarlauTM cages (n = 12; t = 45−50 min after TBP, p = 0.0001), the difference in LTP amplitude between the two groups of rats being highly significant (p = 0.0013).

Finally, the malignancy value M was highly significant, with P = 0.0013 (table 2 ).

Paired sample t‐tests show that the SPE in the matching conditions is highly significant t (30) = 3.55, p = 0.0013 (mean difference = 198.6), but not in the nonmatching conditions ( t (30) = −1.173, p = 0.25, mean difference = −26.6). 3.1.2.

When SMNs were classified by type, a highly significant difference in distribution by RT field location was observed ( p = 0.0013), with all in‐field SMNs being solid tumors and nearly three‐quarters of out‐of‐field SMNs being hematologic malignancies.

4a ), and combining both markers yielded a highly significant association with worse overall survival ( P = 0.0013) (Supplementary Fig. 4b, c ).

The G×G is genome-wide significant for tau , has a nominally significant interaction for Aβ42 ( p = 0.0013), and the pattern of interaction differs for the two traits in a way that creates the rQTL pattern of tau / Aβ42 correlation changes across genotypes (see Fig. 1a ).

Neither CIITA nor PARP4 showed association with endometriosis in the GWA gene-based analyses 14 , although CUBN was nominally significant ( P = 1.35 × 10 −3 ).

The CAMK2B gene that regulates CAMKII is a nominally significant DEG in our meta-analysis (wfisher p -value = 0.00138, adj p -value = 0.0619) and is known to interact with the ARC and RAS genes (enriched DEGs), and also ERK/MAPK pathways [ 69 , 84 ].

Pairwise population F ST values were highly significant (after Bonferroni correction, p < 0.00138), with the exception of the Mochdre and Gavenny sites, and the Mochdre and Lea sites (Table 3 ).

Dimethyl sulfone showed a significant trend ( p = 0.00139).

We also found that RXRA , a heterodimeric partner of VDR , also showed borderline significance (Additional file 11 , p = 0.00139).

A combined statistical analysis of the triticale and wheat results (Figure 1a–c and Figure S3a,b ) showed that this correlation was highly significant ( P = 0.0014, Data S5 ).

Also, the main hospital, which had maximum experience with the use of CP, showed a highly significant mortality benefit in severe COVID-19 (20.5% vs 34.9%; p = 0.0014; OR = 0.48, 95% CI: 0.29–0.80).

The weighted average of this correlation across all psoriasis datasets was highly significant, [r s = 0.31 (0.12, 0.51); p = 0.0014], with no evidence (p = 0.33) of any substantial residual heterogeneity (i.e., there was no remaining variability in effect sizes that was unexplained) ( Figure 3B ).

The differences among the four groups were highly significant in the soleus for unlabeled type I (Kruskal-Wallis Chi2 (3ddl) p = 0.0014) and type IIa fibers (p = 0.0025), and in the plantaris, for type IIa fibers (p = 0.0011).

Despite a three fold reduction in sample size compared to the full CADCZ patient group, the analysis of CAD patients with metabolic syndrome revealed highly significant association with increased effect size ( P = 0.0014, OR = 2.34; P = 0.0016, OR = 2.41; additive and dominant models, respectively).

The results indicated highly significant relationships for both primates and carnivores (Spearman’s r = −0.48, P = 0.0014, and r = −0.50, P = 0.0031 respectively).

Acute Treatment with Typical and Atypical Antidepressants Induce Positive Affective Biases in Rats Acute treatment with the serotonin-specific reuptake inhibitor (SSRI), fluoxetine, induced a highly significant positive bias in rats (0.3–3.0 mg/kg, RM ANOVA, F 3,45 =6.10, p =0.0014, Figure 2a ).

Both concentrations of FermCAE also showed a trend towards better antioxidant activity compared to respective concentrations of AQE, with a significant difference between the 2.5% extract groups ( p = 0.0014).

The difference was highly significant ( P = 0.0014).

Analysis of the concatenated uidA and mutS data with MULTILOCUS yielded highly significant but low θ values when comparing isolates from the Roodeplaat dam catchment with those from the Rietvlei dam catchment ( θ = 0.012 , p = 0.0014) or when comparing phylogroup B2 isolates from the two catchments ( θ = 0.031 , p = 0.0104).

A logistic regression analysis analyzing preoperative feasibility assessment of IORT yielded highly significant test results for the variables “clinical tumor size (cT)” ( p = 0.0014; OR 3.102) and “tumor–skin distance” measured by ultrasound ( p < 0.0001; OR 0.026).

In addition to these decreases, CRP levels showed a highly significant increase (P = 0.0014**), suggesting an inflammatory response related to cancer.

On the other hand, the difference between the asymLSF and symLSF conditions was highly significant ( t (6) = 5.603, p = .0014 for the female-face condition, and the difference between them for the male-face condition was obviously significant but beyond the measurable range.

This difference was highly significant ( p = 0.0014).