Excerpts

With the exception of females aged ≥50 years at years 2 and 4, where the proportional difference did not reach statistical significance, females aged <50 years were significantly less likely (p< 0.0021) to receive LTOWB compared with all other groups ( table 2 ).

The DV CAT regressor itself was highly significant (β=0.021±0.006, t(23)=3.53, p=2.10 -3 ), suggesting that it was the main factor explaining the default bias.

However, comparing methylation frequency among newborns to adults (control population of n = 3602 with the addition of a separate group of 292 young females reported in our study), the difference in methylation frequency between newborns and adults was highly significant (Fisher’s exact test; p = 0.0021).

This association is statistically highly significant ( χ 2 = 12.3, p = 0.0021).

First, we validated the finding in 246 patients with a history of smoking and found a highly significant association with an almost identical hazard ratio compared to the TCGA RNA-Seq data (logrank P = 0.0021; HR, 0.49; CI 0.3 to 0.78 vs.

Overall, it was determined that the presence of an average number ≥ 10 CCR5 pools on CAMLs was a highly significant predictor of worse PFS and OS (PFS HR = 4.5, CI95% 1.8–10.8, p = 0.0021 and OS HR = 3.7, CI 95% 1.4–9.6, p = 0.0137).

In 2007 to 2009, a decreasing trend for mean BMI was significantly observed in those with a high income ( p =0.0021).

A highly significant linear regression equation for the observed data ( p < 0.0021; R 2 = 0.9958) further confirmed a smooth geometric progression in the larval instars of D. helophoroides , validating the geometrical development of head capsule widths across successive instars as proposed by Brooks–Dyar’s Law.

Similarly, the association between N-oleoyl-leucine and future heart failure remained highly significant when further adjusted for free leucine (HR 0.78; 95% CI, 0.66–0.91; p -value = 2.1 × 10 −3 ; median follow-up 12.6 years).

Under the low ionic strength condition, after 63 days, differences between untreated and sodium periodate-treated saliva samples appeared at the limit of significance (paired sample t -test, p < 0.0021).

Highly significant differences were found in 25(OH)D concentrations of women with preeclampsia and the controls (14.75 vs. 22.10 ng/mL, p = 0.0021).

Our array contained 27 SNPs in the vicinity, and only one, namely rs4131943, had a nominally significant association with influenza A severity (p = 2.1×10 −3 , OR = 2.60 95% CI 1.40–4.83); note that the hypothesis-specific number of tests was 27, and that the multiple testing correction would yield p = 0.0567.

A multivariate regression of EFA coefficients with size as independent variable was highly significant (Wilks’ λ = 0.22, F = 2.39, p = 0.0021), demonstrating clear size allometry for the data pooled over all subspecies.

After FDR correction across the two pre-specified correlations, the THBS1–AMH correlation remained significant (Pearson r = 0.351, raw p = 0.036, p _FDR = 0.036; Bonferroni p _corr = 0.072) and the THBS1–LH correlation remained highly significant (Pearson r = 0.496, raw p = 0.0021, p _FDR = p _Bonf = 0.0042).

In addition, the differences between RTs for both phase ranges were highly significant (monkey B: 45.0 ms, n = 16, p = 0.0021483, t = 3.3579; monkey T: 48.9 ms, n = 18, p = 0.011919, t = 2.6571; paired Student’s t -tests, two-sided) and this effect was equally strong for RTs following the reappearance of the initial shape at the end of MCs 2 and 3 (Supplementary Fig. 5 ).

Calcifications vary by pathological stage Both lattice parameters (‘a’ and ‘c’ axes) for HAP showed a decreasing trend with increasing pathological stage, with a significant weak negative correlation between the ‘c’ axis and pathological stage (r τ = − 0.284, p = 2.17 × 10 –3 ) (Fig. 4 a,b).

In contrast, no eQTL was found for FCSHD2 in organ donor (OD)-obtained samples from the same cohort (p = 0.89), while the signal for STARD10 remained nominally significant (p = 2.19 × 10 −3 ).

Unexpectedly, a highly significant ( P = 0.0022) increased frequency of naive B cells in the peripheral blood of healthy controls (HCs) compared with patients with RA was observed ( Figure 1B ).

There was a significant trend that the longer the duration of ACEI/ARB, the higher log [Calc/BSA] ( P = 0.0022) with Jonckheere-Terpstra trend test.

However, improvement in dyspnea scores in the success group was highly significant compared with the failure group ( p = 0.0022).

sporotrichioide s was also demonstrated by a highly significant ( P = 0.0022) negative linear regression of SCIRP contents against culture age during the period of 35–56 days after inoculation.

In a positive/negative thresholded analysis, without taking into account expression level in the positive patients, channel expression did not add predictive value over age alone in the elderly and mid-age patients (older than 65 and 17.28 to 65 years; p = 0.59 and 0.44), but was still highly significant as a bad prognostic factor in young patients (p = 0.0022).

In particular, the reaction time had a highly significant effect ( p -value = 0.0022), confirming its strong influence on the degree of substrate surface phosphorylation.

Protection in the 8 h group was highly significant vs CG (p = 0.0022 Fig. 4C ), and the 47% protection after 24 h approached but did not reach significance (p = 0.0566) ( Table 3 ).

Transplantation showed a trend toward improvement in intestinal tissue damage and a decrease in inflammatory cell infiltration (loss of epithelium: p=0.0022, crypt damage: p=0.0087, depletion of goblet cell: p=0.0433, histological score: p=0.0043) ( Fig. 3E ).