We found a highly significant influence of patient age on LMP1 score (p = 0.004)(Table 1 ).
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Among which tryptophan betaine was the most significant causal metabolite in both AF GWAS data (from Nielsen et al.) (odds ratio (OR) = 0.83, 95% confidence interval (CI) = 0.76–0.90, P = 9.37 × 10 −6 ) and AF GWAS data (from Roselli et al.) (OR = 0.82, 95% CI = 0.76–0.88, P = 2.00 × 10 −7 ), while uridine was nominally significant metabolites in both AF GWAS data (from Nielsen et al.) (OR = 0.58, 95% CI = 0.40–0.84, P = 0.004) and AF GWAS data (from Roselli et al.) (OR = 0.56, 95% CI = 0.35–0.88, P = 0.01).
The difference in the percentage of proliferating cells between combination- and HPßCD-treated NPC1 -/- mice is highly significant ( p = 0.004), with 65.7% less BrdU(+) cells in combination-treated NPC1 -/- , indicating a noticeable difference between both therapies.
However, there was a significant trend toward an increased incidence of AOM with a tympanic bulge by Veau classification ( p = .004).
Secondary outcomes A clearly significant time x group interaction was found for the FERUS, resulting in an F -value of F (1,44) = 9.04, p = 0.004.
After including village (Model 1a, Table 6 ), age group was borderline significant, and village was highly significant (p = 0.004).
Mann-Whitney tests show that these differences of area are highly significant: between clade B2 and other species (p = 0.004), and between clade B2 and all other species from clade B (p = 0.023).
This conclusion is further reinforced by our risk factor analysis, which identified a highly significant association between infection and animal contact ( p = 0.004), as both infected patients reported such contact.
The mean number of individuals offered for sale showed a positive trend related with the human population in the respective city (Estimate = 14.91 ± 4.10, t-value = 3.64, p -value = 0.004) and the number of market stalls selling wildlife (Estimate = 39.54 ± 14.02, t-value = 2.82, p -value = 0.02) ( Figure 2 ).
Using this cut-off value, a highly significant prognostic role for CD8 on RFS was observed (Figure 2 , log-rank test, p = 0.004, cohort 2).
Among the three explanatory variables, spring precipitation had the greatest influence on model performance ( p < 0.001), though the interaction term was also highly significant ( p = 0.004).
Specifically, WT mice performance showed a highly significant negative correlation with weight ( P = 0.004), and APP/PS1 KI mice showed a similar pattern that did not reach statistical significance ( P = 0.052).
The graph shows the highly significant correlation between the real values of grid walk performance and those predicted by the model ( R 16 = 0.718, P = 0.004; Figure 6(a) ).
Only CpG −241 showed a slight trend with diabetes duration (p = 0.004).
In general, concentrations of most antibiotics were lower in the effluent samples compared to influent samples, with differences (at marginal significance) between influent and effluent concentrations observed only for oxacillin (W = 54, p -value = 0.004) and pipemidic acid (W = 53, p -value = 0.006).
According to statistics there is a highly significant dependency of trans -resveratrol content on winery origin ( p = 0.004 ), which supports the results obtained from the canonical discriminant analysis that polyphenolic content is dependent on winery origin.
This corelation was highly significant if patients did not achieve disease remission ( p = 0.004) or minimal disease activity while receiving intensified therapy with biologics ( p = 0.04).
In general, these associations were statistically significant in the USA, UK, Spain and Italy but did not reach statistical significance in Germany and France independently. 10.1136/bmjgh-2020-004611.supp1 Supplementary data HCWs were more likely to report greater than 14 days of symptoms (p=0.004) and moderate-to-severe symptoms (p=0.006) with poor access to PPE relative to excellent access to PPE even after multivariable adjustment including comorbidities ( table 4 ).
However, on day 6 the infectivity of the oseltamivir-treated infected group was 123-fold higher than the control infected group (10 5.4 ffu per ferret), a highly significant difference ( p = 0.004; Fig. 4 d).
The Mantel test indicated a highly significant correlation between environmental variables (exchangeable K + and exchangeable Mg 2+ , and urease activity) and ECM fungal community ( r = .33, p = .004; r = .40, p = .003; r = 0.25, p = .017, respectively). 4.
CAP analysis using forest type as a factor gave strong canonical correlations (δ 1 = 0.89, δ 2 = 0.87) and by permutation yielded a highly significant first squared canonical correlation ( δ 1 2 = 0.789, p = 0.004) and a highly significant trace statistic (1.157, p = 0.001).
It showed a significant trend for acupuncture to decrease the occurrence of OHSS in PCOS women (RR 0.64; 95%CI: 0.47 to 0.87; P = 0.004; I 2 = 0%, Figure 8B ).
Interestingly, an even more and highly significant positive correlation ( p = 0.004, n = 18) was seen if the ratio between the cross-reactive NP205-specific CD8 T cells and the PV NP38-specific CD8 T cells was plotted against the severity of AFN ( Figure 6C ).
Our results indicate a clear trend of decreasing adherence with increasing age (p = 0.004, r = -0.195).
The statistical analysis of the LC-MS measurements shows a highly significant increase (p = 0.004) of the [2,3- 13 C 2 ]lactate-to-[2,3- 13 C 2 ]pyruvate ratio upon activation, with a 95% confidence interval of [4.54, 28.76] (Fig. 3F ).