Excerpts

Antibody-positive stained cells were much more abundant in the vitamin D-deficient group when compared to the control group, and the difference was highly significant, especially for PRB ( P < 0.005; Figure 2C and D ).

In contrast to the lack of effect on steady-state levels of PIns, FLUO inhibited the rate of incorporation of 3 H-inositol into PI, PIP and PIP 2 compared with controls; each of these highly significant ( p < 0.005) decreases indicated by the symbol (φ) was directly proportional to the decrease in the steady-state level of inositol (the average decrease in the five components in Figs. 3a, c, d was 45 ± 2%).

2 ) from infected ( n = 4) and non-infected ( n = 8) animals revealed for EAAT2, GluA2, Shank3, and GABA A R α1 a highly significant main effect of infection status ( F 1,10 = 12.93; p = 0.005, two-way repeated measures ANOVA with protein as a within-subject factor and infection status as a between-subject factor) while no significant effect of protein or interaction was observed (all p > 0.804).

We used FLIM-FRET analysis to measure the NDC80 binding in groups of sister kinetochores with similar K-K distances, and observed a highly significant positive correlation (p<0.005) between NDC80 FRET fraction and K-K distance ( Figure 3D ).

Differences were considered as “highly significant” in cases with p -values ≤ 0.005, as “significant” with p -values ≤ 0.05, as “borderline significant” with p -values between 0.05 and 0.1, and as “not significant” (n.s.) with p -values ≥ 0.1.

When accounting for geographic proximity among sites using a partial RDA, WinSST was again the top predictor of both outlier and nonoutlier genotypes based on model selection, although this was marginally nonsignificant for the nonoutlier SNPs ( F = 13.03, p = .005 and F = 2.41, p = .055, respectively).

5E ) and RFS difference between Vigil and placebo was highly significant in this population (median not reached vs 11.8 months, HR = 0.21, p = 0.005) (Fig. 5F ).

The standard error of the average mean difference in oxygen uptake, as determined by paired data analysis, was 1.13 and is highly significant (p < 0.005) .

The permutation test analysis showed ( Figure 3 A) that the OPLS-DA model had a goodness-of-fit R 2 Y value of 0.950 and a predictability Q 2 value of 0.727 after 200 random simulations, both of which were highly significant levels ( p < 0.005).

A marked increase in PD-1 expression was noted in HIV-specific CD4 + T cells from controllers and treated patients, this increase being highly significant ( P < 0.005) in both the cTfh and the MemX5 − subsets ( Fig. 3A and B ).

Indeed, the overall effect of fenofibrate in the presence of marked dyslipidemia was larger than that in all other groups, with borderline significance of treatment by group interaction: marked dyslipidemia group: 27% risk reduction (adjusted HR 0.73 [95% CI 0.58–0.91], P = 0.005); all others: 6% risk reduction (0.94 [0.83–1.06], P = 0.321; P interaction = 0.053) ( Fig. 2 ).

The trend effect calculated by treating variables as ordinal categorical variables in the multivariate logistic regressions showed that there is a significant trend of improvement in ECD with an increase in the duration of breastfeeding (trend effect, p = 0·005) and in the number of books (trend effect, p = 0·008).

cytoprotective or pro-inflammatory), differences from baseline were highly significant at the 95% confidence level by ANOVA (F 1,52 = 8.82, p < 0.005 for cytoprotective genes and F 1,46 = 9.25, p < 0.004 for pro-inflammatory genes) (Fig. 6c ).

There was a statistically significant within group improvement in VAS pain scores from baseline at all timepoints for the PRG combined group, with highly significant improvements seen at months 3, 6, 9 and 12 (p ≤ 0.005) while VAS pain scores in the placebo group showed marginal improvement.

There was a highly significant difference ( p < 0.005) between the high and low FeNO groups in the number of recorded coughs in 24 h.

When groups of individuals were analyzed, it was observed that there was highly significant control of bacterial replication in the presence vs. the absence of non-adherent PBMC from vaccinees ( n = 11); P < 0.005 for cultures with LVS-infected or SCHU S4-infected cells, whereas addition of non-adherent PBMC from naïve individuals ( n = 11) did not result in significant control ( P > 0.05) of bacterial numbers in any of the cultures (data not shown).

The NS clonal line showed a significant effect of H 2 O 2 exposure on average number of tentacles present on days 5–12 (p<0.05), with highly significant effects on days 5, 11, and 12 (p<0.005).

These effects failed to reach significance at the p < 0.005 level.

In a general linear model of body condition index as a function of Julian day, breeding state, and an interaction term, all three terms were highly significant (p<0.005).

[ 39 ] reported markedly higher risks for females, with ERR/Gy of 4.22 (90% CI 1.72 to 7.21) for all CVD, 6.17 (90% CI 2.44 to 10.92) for ischemic heart disease (IHD), and 2.67 (90% CI < 0 to 9.79) for CeVD, compared with ERR/Gy for males for the same endpoints of 0.20 (90% CI 0.07 to 0.36), 0.16 (90% CI -0.01 to 0.34), and 0.48 (90% CI 0.10 to 0.91), respectively; these differences were highly significant for all CVD ( p = 0.005) and IHD ( p = 0.004), but not for CeVD ( p > 0.50) (Tables 2 and 3 ).

In fact, the up-regulation in expression for all three treatments between 8 hr and 24 hr was highly significant (p < 0.005 in all cases).

Layer-by-layer comparison resulted in slightly significant differences revealed by Kruskal–Wallis ANOVA (χ 2 = 16.7, p = 0.005), although post-hoc tests did not show any relevant differences between layers (Fig. 4 b red bars, 4 d, n = 4).

This trend was highly significant for the toxin genes of Rhs loci 1 and 2 (Spearman’s rank correlation ρ = −0.388, P < 0.005, and Spearman’s rank correlation ρ = −0.563, P < 0.001, respectively), although this trend was not observed for Rhs locus 3 (Spearman’s rank correlation ρ = 0.375, P = 0.034).

L-Arginine-Related Biomarkers in Relation to Chronic Airflow Obstruction (CAO) There was a highly significant difference in SDMA serum concentration between participants with and without CAO (0.518 [0.461–0.616] vs. 0.494 [0.441–0.565] μmol/L; p = 0.005), but no significant difference in ADMA concentration (0.516 [0.447–0.594] vs. 0.505 [0.447–0.557] μmol/L; p = 0.20) ( Table 3 and Figure 4 a).

Influence of irrigation levels on above-ground biomass and grain yield of wheat at harvest The irrigation treatments had a highly significant effect ( p < 0.005 ) on both the aboveground biomass (BY; t ha −1 ) and grain yield (GY; t ha −1 ) of wheat across all three study years (Fig. 3 , Table S1 ), as well as on the average over the three years (Table S1 ).