Excerpts

This in-phase synchronicity was quantified by means of the synchrony index (SI), showing a highly significant difference (P < 0.00002) between PC-BK −/− (0.13 of ±0.04, n = 18) and PC-WT pairs (0.03 ± 0.02, n = 7).

Negr1 -WT mice demonstrated improvement in the time required to find the hidden platform (escape latency) over the first three training days and there was a highly significant improvement from day 1 to day 3 ( p = 0.00002).

When the entire sample was evaluated together, the facial asymmetry scores of the scoliosis group were significantly higher than those of the non-scoliosis group, and this difference was statistically highly significant (U = 1848.5; p = 0.00002).

For this case, all parameters were reported as extremely significant ( p -Value < 2 × 10 −5 ) with the following coefficients: (10) k 13 = 0.74957 · ( w t 13 ) 3.283 + 0.07617 · T 13 Although other polynomial alternatives were contemplated as well, including additional second or superior order coefficients did not improve the prediction capabilities. 3.2.2.

Increasing the number of marginally significant height SNPs in the estimates of inbreeding coefficients increased the difference with respect to the random SNPs (P < 2 × 10 −5 for top 2,500 SNPs and P < 9 × 10 −8 for top 5,000 SNPs), further providing evidence of height-based assortative mating in the ARIC European cohort (Tables 2 and 3 ).

ID 653 was therefore experimentally regrouped into the viral group, which resulted in a highly significant p-value ( p = 2e -5 ; Fig 7B and 7D ). 3.2.2 Bacterial No statistically significant group differences could be detected for bacterial presence in this investigation.

As a result, a significant difference between the prisms with and without cyanobacteria was detected (Figure 2) for bending tensile strength (t = 2.9717; p = 0.0180) and a highly significant difference for compressive strength (t = 5.75; p = 0.00002).

Compared with the CC-Random group ( Appendix A:Supporting Information S2 ), The relative matched frequency (RF) of the BFE-mRNA sequence was more obvious in these two regions, and the difference in RF at the 3’end was highly significant ( t -test, p < 0.00002).

Since our GWAS hits are of marginal significance, the false discovery rate within this range of P -values is high (for example, at P -value≤2e−05, the FDR is 0.66).

Importantly, we also observed a highly significant inverse correlation with the expression of AR (P = 0.00002) (Figure 1 A).

The increase in predictive power is highly significant ( p < 2 × 10 −5 ; paired Wilcoxon test).

The observed difference in the monthly prevalence of the DEC was highly significant in the month of March (P = 0.00002) ( Table 3 ).

For the U-87 MG glioblastoma cell line, on which the present study was focused and for which correspondingly more experiments were performed, the enhancement was statistically highly significant ( p = 2 × 10 −5 ).

Results Correlation analysis between CNV values obtained with the two methods was slightly significant ( R = 0.413, p = 0.00002), because of the wider data dispersion in qPCR compared with ddPCR.

Based on the observed data, a negative trend of four species lost per census (per 5 years) was observed ( figure 4 d ; average p = 2 × 10 −5 from bootstrap least-squares linear regression).

Strikingly, ontological analysis established that six of the 17 CIS genes have transcription factor activity ( Nfia , Tead1 , Tgif2 , Nfib , Myt1l and L3mbtl4 ), a highly significant excess relative to expectation (FDR corrected p-value = 2×10 -5 ).

By 24 hours, the difference was highly significant ( P = 0.00002), with 30% and 40% of patients on nalbuphine experiencing no or mild pain compared with 15% and 25% of patients in the morphine group, respectively.

Group status had no significant main effect on amygdala activation but the interaction between group and experimental phase on left amygdala activation was highly significant (peak voxel xyz: -24 -2 -14, cluster size: 97, F(1,126) = 19.26, Z-score = 4.07, p = 0.00002).

To address the potential physiological significance of neutrophil count normalization by hRabMab1+gem/PTX in the PaCa-44 model, we performed correlation analysis between circulating neutrophil counts and tumor volumes across all 4 cohorts; a highly significant positive correlation between neutrophil counts and tumor volumes was identified (R = 0.628, p = 0.00002), mirroring findings reported in human patients [ 22 ].

Further, the differences between them were highly significant (Mann-Whitney U -test, P = 2 × 10 −5 ).

The number of observed confirmations is highly significant ( P < 2 × 10 −5 , Z -score = 77.2), because no more than 16 matches (1%) were observed in 50,000 simulations that apply a transcription factor's annotations to its shuffled motifs ( Fig. 3D ).

Indeed, used alone, CD9 based sorting yielded a highly significant, 14-fold enrichment in CD140a + /PDGFRα + cells relative to their unsorted dissociates (t-test, p=0.00002).

All model terms were highly significant ( p < 2e − 5), with acidic group count (nAcid) displaying the most significant effect ( p = 3.2e − 7) (Fig. 2 e), consistent with the group-wise investigation of LMs (Fig. 2 a).

We observed a highly significant positive correlation between MSI/hypermutation frequency and the total number of somatic mutations per cancer after integration by OncoMerge (R = 0.68 and p value = 2.0 × 10 −5 ).

The difference between the cumulative growth in the number of PVCs in the control and riluzole groups was highly significant, at p<0.00002.