Excerpts

In all these comparisons, the difference between control antibody and fremanezumab was highly significant (F 1,62/64 = 21.40–23.68, p < 0.0005) but there was no difference between the three trigeminal partitions V1-V3 (F 2,62 = 0.80, p = 0.45), between females and males (F 1,64 = 0.65, p = 0.42) and between different waiting times (F 1,64 = 0.64, p = 0.43).

There was also a significant trend ( P = 0.0005) of increasing PC3 level with increasing pack-year category (Table 6 ).

Results The regression analysis indicated a large and highly significant Roemer effect (t = 5.6, p<.0005; see Table 3 ).

All p -values are two-sided; p < 0.05 is considered significant, p < 0.005 highly significant, and p < 0.0005 very highly significant.

In contrast, this difference was markedly significant ( p > 0.0005) in H-DNA mice on the HFD compared to the CD.

As shown, the msRT for the familiar face was ~60 ms longer than for each of the other faces, with a highly significant group average effect of 73 ms when comparing the familiar face to the average of all non-familiar faces (Fig. 3a , left panel, p = 0.0005 in a non-parametric permutation test, see Methods).

Highly significant trends validate these findings further for glioma ( P =0.0005) and colorectal cancer ( P =0.0010).

Nosema levels: While the change in nosema levels in the FL trial was not significantly different between treatment groups (F 4,95 = 0.47; P = 0.7586), a highly significant difference in nosema spore levels was detected at the end of the PA trial (F 2,57 = 8.62; P = 0.0005) ( Figure 4 ).

The difference in level of relatedness between breeding pairs and random pairs was estimated at 0.07 and was highly significant (10,000 simulations, one-sided p -value = 0.0005).

A one-way ANOVA showed a highly significant cohort effect ( F = 14.20, p = .0005, η 2 = 0.69), and a pairwise post-hoc Tukey-HSD test computed with the onset indices for the ND-CI and AD-CI cohorts were not significantly different ( p = .98), but did reveal a significant difference between ND-CI and NH-acoustic ( p = .0007) and AD-CI and NH-acoustic ( p = .0018).

We thus fitted the additive model, and, in this model, the method of density estimation was not significant (p = 0.1266) while the effect of the log.BodyMass was highly significant (p = 0.0005, conditional R 2 = 0.90).

We identified several highly significant ( P < 5 × 10 −4 ) maternal QTL influencing total body weight, organ weight, and fat pad weights in both sets of subcongenics.

Statistically significant difference was as follows: **** highly significant (p<0.00005), *** moderately significant (p<0.0005), ** significant (p<0.005), * less significant (p<0.05).

THOMSON highly significant (P< 0. 0005) increase in liver weight occurred in response to C. parvum.

In addition, highly significant loci were detected on chromosome 8 of 320-02 at marker P14M37-134 ( P < 0.0005) and on chromosome 9 of 10618-01 at marker E32M48-233 ( P < 0.0001) (Table 2 ).

For this group, Bartlett’s test indicated the adequacy of the data to apply FA with a p -value highly significant ( p < 0.0005), leading to the rejection of the null hypothesis H0: The correlation matrix is equal to the identity matrix.

Top associated gene sets overlapped across module builds with highly significant p values (Fisher’s test) with the exception of vacuolation ( Figure 1 C, red solid line indicates p = 0.0005).

In contrast, Lr GtfC 100-23 W240C showed a highly significant positive thermal shift in the presence of both UDP-GlcNAc or UDP-Glc ( p < 0.0005).

Treatment with 1 mM SY-LB-57 also caused a highly significant decrease in cell viability in C2C12 cultures compared with control (85% decrease; **** p < 0.0005; Fig. 3 C).

The exponential model on a log e H vs Y scale also demonstrated a highly significant linear relationship (F 1,5 = 137.08, P < 0.0005, R 2 = 0.97), with a slope of −0.1635 (95%CI -0.1994 to −0.1276) and an intercept of 333.1882 (95%CI 261.1155 to 405.2608).

In spring, prevalence reached 93.3% in European hake compared to only 12.2% in greater forkbeard; here, the odds of infection were nearly 100‐fold higher in hake, and the difference was highly significant (OR = 99.0, p = 0.0005) (Table 4 ).

The differences between full-conditioning and the control group were highly significant whether evaluated as the number of women being adhesion free (P = 0.0005), as the severity score (P < 0.001 for all localizations Figure 2 ) or as the density and area involved around the left ovary (P = 0.001 and 0.004), the right ovary (P = 0.0003 and 0.0003), between uterus and bowels (P = 0.0002 and 0.0013) and between bowels and side walls (P = 0.0001 and 0.0001).

Although the CGGGG indel did not reach statistical significance independently in all three cohorts, the combined analysis revealed a clear association signal between the CGGGG indel and MS (p = 0.0005), with the longer allele (4×CGGGG) as the risk allele.

These titers exceed by >1 log the highest titers detected by earlier assay methods (29-31), and the difference between the seropositive patients and normal controls was highly significant (p < 0.0005).

However, in the built area, there was a positive and moderately significant correlation between the abundance of phlebotomine species with humidity (rho = 0.705, p value = 0.0005) and accumulated precipitation (rho = 0.636, p value = 0.0013). 4.