The correlation analysis between the Firmicutes abundance and striatum RD shows a negative association ( r = 0.7, p = 0.02, Figure 4D ), while the striatum FA shows a positive trend ( r = 0.6, p = 0.06, Figure 4B ).
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A positive trend was also observed in the application of pressure after needle removal (p = 0.060), although this did not reach statistical significance.
33 37 One additional study, 39 a CBSM web-based programme, reported a positive trend in functional well-being (p=0.06) and emotional well-being (p=0.07) on the FACT-G subscale.
The variable VPR showed a positive correlation with SCD ( p = 0.04) and a positive correlation with CAD ( p ≤ 0.01), while also presenting a positive trend with SIW ( p = 0.06).
The correlation between SKP2 protein levels and IC50 values showed a positive trend (Pearson r = 0.7767), with a p-value near significance ( p = 0.06), (Supplemental Fig.
However, the average meditation composite score was negatively associated with %N1 ( p = 0.017), and showed a positive trend with %N2 ( p = 0.060) (Figure 5 ).
However, there was a positive trend-level correlation between RT difference and M-ratio scores, Spearman’s r = 0.32, p = .06, BF 10 = 1.02 (Fig. 4 B), suggesting that—if anything—lower RT differences, which are indicative of better mentalising, are associated with lower M-ratio.
Probiotic use was independently protective against blaTEM carriage (adjusted odds ratio = 0.19, 95% CI = 0.05-0.69, p = 0.011), whereas MGE detection showed a positive trend (p = 0.060).
Although the expression of PSMA3-AS1 in relation to the size of the tumor was not statistically significant, a positive trend towards higher PSMA3-AS1 expression in bigger tumors was demonstrated ( p = 0.06), ( Figure 6 ).
DST-Forward Regarding short-term memory span (DST-forward), conventional meta-analysis showed a positive trend for partially immersive VR (Group B) over active controls (Group C) (n = 55; SMD = 0.87, 95% CI [−0.03, 1.78], p = 0.06; I 2 = 60%), while fully immersive VR (Group A) did not significantly differ from passive controls (n = 370; SMD = 0.13, 95% CI [−0.07, 0.34], p = 0.20; I 2 = 0%) ( Figure S9 ).
Among carriers, there was a positive trend between bacterial density and M.pneumoniae copy number (rho 0.23, p = 0.06, Supplementary Figure S3B ).
There also appears to be a positive trend with the tree composition of the genera Eugenia , Podocarpus, Olea , and Washingtonia ( Figure 4 d), but this relationship is not statistically significant ( p = 0.060).
There was no significant association between the whole‐blood IGS and LINE‐1 transcription expression (Figure 1D ), despite a positive trend ( P = 0.06) between the IGS and circulating IFN‐α (data not shown).
Among older women (≥37 years), a positive trend was observed: greater insomnia severity was associated with higher BMI ( β = 0.59, 95% CI: −0.03 to 1.21), a result that approached statistical significance ( p = 0.06).
The subgroup analysis suggested that the combination therapy not only provided significant improvement in PFS (HR = 0.60, 95% CI 0.39–0.90; p = 0.01), but also had a positive trend to prolong OS (HR = 0.69, 95% CI: 0.46–1.02; p = 0.06) in patients with brain metastasis (Fig. 4 A, B).
Knowledge score, while showing a positive trend, did not reach statistical significance in the multivariable model (OR = 1.181, 95% CI: 0.993–1.404, p = 0.060).
In the overall population, OS was significantly improved in the toripalimab group, with 17 months in the experimental arm vs 11 months in the placebo group (HR = 0.58, 95%CI: 0.43-0.78; P = 0.0004), maintaining a positive trend in PD-L1 CPS ≥ 10 subgroup, though without reaching statistical significance (17.0 months vs 10.9 months, HR = 0.64, 95%CI: 0.40-1.03; P = 0.06)[ 26 ].
Further subgroup analysis revealed that HbA1c levels ≥6.5% were significantly and positively associated with anterior circulation stenosis ( r =0.13, P =0.03) and showed a positive trend with posterior circulation stenosis ( r =0.13, P =0.06).
Pooled effect size analysis demonstrated a RR of 1.11 (95% CI = [1.00, 1.24]), indicating a positive trend favoring the treatment group, but this did not reach conventional statistical significance ( p = 0.06).
A positive trend was observed for folic acid intake, although it did not reach statistical significance ( p = 0.061).
However, peak troponin levels during hospital admission showed a positive trend with the IMR ( r = 0.405, P = 0.061) at follow-up assessment.
To investigate the degree of immune cell infiltration at the tumor site in the two subgroups of patients, we further explored the relationship between TIL fraction (estimated by T cell receptor sequencing (TCR-seq)) and TASL expression in the tumors of both groups of patients and found that in the NA-aPD1 group, there was a positive trend of correlation between TIL fraction and TASL expression ( R = 0.539, P = 0.061), whereas in the A-aPD1 group, TIL fraction was not associated with TASL expression ( R = -0.164, P = 0.555, Fig. 4 F), implying that in the NA-aPD1 subgroup, high TASL expression may be positively correlated with the activation of adaptive immunity.
No significant correlation was observed between the grey matter fraction within the voxel and the GSH concentrations, although a positive trend was seen between GSH levels and the grey matter fraction (rho = 0.236, p = 0.061).
However, higher zonulin levels showed a positive trend towards increased duodenal bacterial load (r s = 0.36, p = 0.061) and zonulin correlations also extended to obesity associated parameters such as body mass index (r s = 0.65, p = 0.01E−02), waist circumference (r s = 0.47, p = 0.009), and hip circumference (r s = 0.53, p = 0.003) (Supplementary Table 3 ).
Despite not showing a statistically significant difference, when comparing the bothersomeness of symptoms in each group, there was a positive trend towards better outcomes in the cineole group ( p = 0.061; see Figure 2 ). 3.2.4.