“an overall trend”

Nevertheless, meta-analyses and systematic literature reviews reveal an overall trend of worsening sexual functioning and decreased frequency of sexual activity during the pandemic (Delcea et al., 2021b ).

The NDVI WS values were evaluated by comparing the single-year boxplot for each portion of the AOI ( Figure 14 ), revealing that the 02_Camp_Altiplano area exhibits an overall trend of stability during the WS.

In non-progressing patients, there was an overall trend for decreasing ctDNA values over time, and undetectable ctDNA correlated with spontaneous clinical regression in some patients ( 85 ). ctDNA may also serve as a minimally invasive marker for predicting FL progression and its transformation into diffuse large B-cell lymphoma.

Since the analysis used 2016–2020 data, COVID-19 restrictions may have affected use of screening and diagnostic services and potentially impacted NAS identification in 2020; however, given the 2020 data is part of an overall trend of declining NAS rates of four years in a row the presenting data likely accurately mirrors the NAS birth rate.

Inter-regional temporal trends varied with three patterns being typical: a distinct peak of ANS primary detections in the 1995–2015 timeframe, an overall trend (positive slope) of increased detections through time or a relatively stable rate of detections ( Figure 3 ).

In aged animals, there was an overall trend toward decreased phase and increased resistance as compared to young animals, whereas reactance values were lower in aged animals at frequencies below 60 kHz and then were higher at frequencies beyond that value.

As an overall trend, the group of enterprises in quantile 2.5 was significantly different from the group of enterprises in all other quantiles, with a shorter average duration.

However, in patient glioblastoma cultures, no significant changes in tumour cell numbers were observed between the same groups, although an overall trend for higher efficacy of AZ over TMZ was speculated (Fig. 3 A).

An overall trend toward an increase in BMI was observed at the long-term follow-up that however did not reach statistical significance due the small sample size, but in the majority of participants BMI changes were stable or improving over time [ 80 , 81 ].

Although there were no statistically significant changes in antigen-specific T cell responses with training, there was an overall trend for an increase in the response to VZV, Mammaglobin, Mucin-1 and Survivin, especially in the partly-supervised exercise group.

Thus, hyperbolic discounting is not identified as an overall trend within the sample.

Concerning the used atmosphere, oxygen or nitrogen, an overall trend can be seen ( Figure 3 a): with values ranging from 12 to 108 kA/m and an average of 40.7 kA/m, the particles synthesized with O 2 show significantly higher H C , compared with the reaction under N 2 , where H C ranges from 1 to 32 kA/m with an average of 19.8 kA/m.

An overall trend of increasing concentrations of reducing ends (expressed in galactose equivalent) was observed, which showed that the hydrolysis of glycosidic bonds resulting from the depolymerization reaction produced new reducing terminal galactoses over M n reduction.

Regarding DLPC ( Figure 7 B,E), an overall trend of a decrease in bilayer thickness and a concomitant increase in APL in the presence of the protein was also found, except bilayer thickness in the PS-raft, where no significant change in bilayer thickness due to the protein was evident.

The analyses were performed to obtain an overall trend for all participating countries together and for each country separately.

An overall trend of slow progression of disease and requirement of keratoplasty in less than one-fourth of the study population was observed.

As an overall trend, the oil–water IFT values for the three lignin carboxyl betaines decreased and then increased as the temperature increased within the experimental temperature range, and the ultra-low IFT values were achieved at the temperatures ranging from 50 °C to 90 °C.

The CD45 mid CNS-resident microglia also showed an overall trend towards a less inflammatory functional phenotype in animals treated with B cells at the time of injury.

Although we found an overall trend towards decreased functional connectivity in patients with ARHL compared with older individuals with normal audition, our results may have been limited by insufficient differences in hearing thresholds.

This analysis revealed relatively weak signs of host cell defense system activation and an overall trend of parasite benefiting changes.

The existing literature suggests that there was an overall trend towards increased alcohol consumption and a clear trend towards increased use of other substances use in the general population during COVID-19 [ 76 ].

An overall trend toward an increased relative abundance of ASVs under intermediate and severe water deficit was observed for the fungal phylum Ascomycota (Fig. 2D ).

For non-drinkers, among both overweight and obese categories, an overall trend shows a significant decline in the prevalence between 1999 and 2017 ( Fig. 4 ) albeit with a higher decline of over 2% per year observed in obese individuals (APC, −2.06%; 95% CI: −2.95%, −1.17%).

While there are inconsistent results, there is an overall trend illustrating an increase of cathepsin levels in biofluids and tissues of AD and a decrease in PD.

The phasor plot revealed not only some heterogeneity across cells but also an overall trend, in which greater N res exhibited more left-shifted phasor values, corresponding to longer fluorescence lifetime and greater R E .