Barely Significant
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did not reach statistical significance

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did not reach statistical significancep = 0.0521.0× alphaplainly factual
In contrast, patients with PE exhibited significantly higher methylation levels in T compared with D tissues ( p = 0.035), while A tissues showed a trend toward higher methylation compared with D tissues, although this difference did not reach statistical significance ( p = 0.052).
Compared to those implanted after 42 months, children implanted between 25–42 months showed a trend toward better outcomes, though this difference did not reach statistical significance (Estimates = −6.01, SE = 4.06, 95% CI [−14.05, 2.04], t = −1.48, p = .142).
While no specific Ratio of Ratios (RoR) was significantly different from 1 for any pair, certain comparisons, such as "Non opioid analgesic plus Opioid: Non opioid analgesic" (p=0.0782) and "NSAID plus Non opioid analgesic plus Opioid: Non opioid analgesic" (p=0.0759), exhibited marginal p-values, suggesting a possible trend towards inconsistency that did not reach statistical significance.
At the protein level, inhibition of miR-99b-5p in MDA-MB-231 cells resulted in a statistically significant upregulation of DR5 and BAK1, while BCL-XL expression exhibited a decreasing trend that did not reach statistical significance ( Figure 2D ).
Similarly, the Systemic Immune-Inflammation Index (SII) [neutrophil × platelet/lymphocyte] showed an increasing trend in ICU-admitted patients; however, this did not reach statistical significance, possibly due to the limited sample size and heterogeneity of the study population [ 22 ].
The results showed a trend toward partial recovery of associative learning ability following gene therapy, though it did not reach statistical significance, likely due to inter‐animal variability and a limited sample size compared to rodent behavioral studies (Figure S10 , Supporting Information).
did not reach statistical significancep = 0.74915.0× alphaplainly factual
An interesting finding revealed in this study was a positive trend toward an association of high immunohistochemical expression of RUNX2 with larger tumor sizes; however, this did not reach statistical significance (p = 0.749) (Table 2 ).