However, RT‐qPCR analysis of Nod1 , NLR family CARD domain‐containing protein 4 ( Nlrc4 ), Nlrc5 and Nlrp10 did not reach statistical significance, although it showed an expected trend, possibly due to their subtle alterations or individual variation (Fig.
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genome‐wide cfDNA) did not reach statistical significance, a trend towards significance was observed and may reach statistical significance in a larger sample size.
Similarly, there was an observed trend indicating that patients with PA with posttreatment PRA levels between 1 and 2 ng/mL per hour had a lower incidence of MACE compared with those with PRA levels either <1 ng/mL per hour or >2 ng/mL per hour; however, this trend also did not reach statistical significance.
Intriguingly, the perigonadal fat dissected from males or females at 9 months of age showed a trend for an increase by 5–12% in the mutant mice of both genders, but this difference did not reach statistical significance.
However, patients aged 45–65 showed a trend toward a lower likelihood of completing vaccination compared to those under 45, though this association did not reach statistical significance ( p = 0.119).
BDNF showed an increasing trend but did not reach statistical significance.
There was also an overall trend toward decreasing the number of steps in the knot-tying process when comparing the original stimuli to the knots demonstrated by the last participant, though this did not reach statistical significance.
A strong trend toward a higher rate of deaths (8,8% vs 0%) was also observed in not vaccinated patients, although it did not reach statistical significance, probably due to the small number of evaluated patients.
However, it could not be determined whether this was due to changes in interneurons located in the stratum oriens (Or) or pyramidale (Pyr) as the densities in those subregions showed a trend but did not reach statistical significance ( Fig. 1C ).
Several studies revealed that patients with coexisting TP53 mutations treated with EGFR-TKIs showed a trend toward lower ORR, shorter PFS, and OS compared to patients with wild-type TP53 that did not reach statistical significance ( 28 – 31 , 68 ).
Area-under-the-curve (AUC) and mobility fraction (m.f.) analyses, indicating the overall proportion of highly mobile proteins within the nucleus, showed a trend for decreased mobility of endogenous fusion proteins relative to their over-expressed forms but these did not reach statistical significance (AUC = 67.80 and 82.61, m.f. = 44.61 and 58.81%, respectively, for -mAvicFP1/GFP [Fig. 3 g]; AUC = 68.12 and 76.95, m.f. = 41.93 and 48.51%, respectively, for -mCherry [Fig. 3 h]).
Although patients with detectable ctDNA prior to adjuvant chemotherapy showed a trend toward shorter RFS compared to ctDNA-negative patients, the association did not reach statistical significance.
Although a positive trend emerged, it did not reach statistical significance for most states ( SI Appendix, Fig.
In contrast, the S155E mutant showed a trend to increased promoter activation under unstimulated conditions that did not reach statistical significance.
Compared with the OPS group, the MIS group showed a trend towards lower overall complication rates, but this did not reach statistical significance (OR=0.78, 95% CI [0.59–1.03], P =0.08), neither for PD (OR=1.10, 95% CI [0.43–2.79], P =0.84) nor for DP (OR=0.73, 95% CI [0.53–1.01], P =0.06).
A positive trend in daytime functioning was observed upon chamomile consumption, though it did not reach statistical significance. 142 By contrast, 2 methodologically identical studies in 77 elderly hospitalized individuals with a mean age of 74.3 ± 10.6 years, 143 and 110 postmenopausal women aged 50-60 years, 144 found that 400 mg of chamomile extract twice a day for 4 weeks significantly improved PSQI sleep scores following treatment (from 8.8 ± 4.3 to 5.0 ± 3.7, P < .001, and from 13.68 ± 1.68 to 9.07 ± 1.53, P = .001, respectively) compared to placebo.
The results indicate that changes in LFP and rsfMRI connectivity showed a trend toward correlation, but the relationship did not reach statistical significance ( r = 0.52, p = 0.057).
Descriptive data showed that treatment-naïve patients receiving RTX experienced no glucocorticoid-related adverse events, whereas relapsed patients exhibiteda statistically significant reduction in steroid dosage and a decreasing trend in relapse frequency after RTX, although the latter did not reach statistical significance.
The interstitial scores showed a trend to decrease by ISD017 treatment, although it did not reach statistical significance (Supplementary Fig. 5).
Comparison of cell-type composition revealed that the proportion of CD25 + cells within the CD4+ T cell compartment showed an increasing trend in non-survivors compared with survivors at both the sample and cell levels, although this difference did not reach statistical significance (Additional file 2: Figure S3).
In the pairwise correlation analyses, all significant associations between CBF and p-tau181 were also negative, and most other brain regions showed a negative trend but did not reach statistical significance ( Fig. 2 ).
Our longitudinal study found that BRI did not reach statistical significance, although it approached significance, indicating that BRI may not be a reliable predictor of CKD progression.
Phosphorylated TH, phosphorylated CaMKII, and dopamine protein levels showed an increasing trend in the model group, although these differences did not reach statistical significance.
While our analysis of axon projections did not include the VMH, we observed a small trend in the predicted direction when we compared BLA innervation between SERT-Cre and ePET-Cre mice, but this did not reach statistical significance.
An increasing trend was observed in ELSA but did not reach statistical significance.