“did not reach statistical significance”

As shown in Figure 1 A–C, the expression levels of Acta2 and Col1a1 were significantly elevated in the CKD group compared with those in the Normal group ( p < 0.001), whereas Tgf-β1 expression showed an increasing trend but did not reach statistical significance.

The age distribution showed an increasing trend in vaccination rates with age (21.3% in individuals aged ≥60 years), although this did not reach statistical significance (p = 0.104).

Furthermore, our data showed a trend toward higher serum 1,25(OH) 2 D 3 concentrations in the suboptimal and optimal groups compared with the deficiency group, although this difference did not reach statistical significance.

In the present study, glimepiride showed a trend towards decreasing HDL‐cholesterol, but this did not reach statistical significance.

The relative permeability of TSC2 mutant BMEC barriers showed a trend towards higher permeability than barriers from control BMECs for the 3 kDa dextran, but the difference did not reach statistical significance (Fig. 2 A).

However, while their conclusions suggested a benefit of HBO, their pooled analyses did not reach statistical significance, indicating only a nonsignificant trend.

A decreasing trend in serum SOD levels was noted with increasing severity of premature canities; however, it did not reach statistical significance [Tables 3 , 4 and Figures 1 , 2 ].

Serum decorin levels showed an increasing trend with advancing CKD stage; however, these differences did not reach statistical significance and were not correlated with renal function parameters.

Consistent with this previous report, we also observed a significant reduction in the Idh3a, Slc25a24, and Pck2 protein levels, while Clpp and Me2 showed a decreasing trend that did not reach statistical significance.

The plasma BHB levels of iSIRT3 mice fed HFD were not different from those of mice fed CD and showed an increasing trend compared to S3fl mice on HFD, which did not reach statistical significance.

≥12 months) showed a trend toward association with OS, although this did not reach statistical significance [HR: 0.63 (95% CI: 0.33-1.21); p = 0.16], as shown in Figure S1A-D (see online supplementary material for a color version of this figure).

Although other variables did not reach statistical significance, there was an observed trend suggesting that older individuals and those with diabetes may have a higher likelihood of being seropositive for SARS-CoV-2. 3.4.

Considering all experiments with Cs + , in those cells in which a resonant profile was resolved at subthreshold depolarized potentials without action potential discharges (∼−65 mV; 4 cells), resonance strength showed a trend to decrease in Cs + , though the difference did not reach statistical significance (Q = 1.27±0.15 for Control and 1.03±0.03 for Cs + ; p = 0.054; paired t-test).

Body weight showed a trend toward reduction but did not reach statistical significance.

Rades et al [ 55 ] tested a simple reminder app for skin and mouth care during radiotherapy; while it did not reach statistical significance, it showed a trend toward fewer severe side effects.

A positive trend in tumour-localized CAR T cell mass was observed for mice bearing cytokine-expressing tumours compared with those with unmodified tumours (+37% in SK-N-AS and +18% in SK-N-BE2c), although this did not reach statistical significance.

However, while we observed a negative trend with PPP4C expression, the adjusted p value did not reach statistical significance using CIBERSORT ( online supplemental figure 7 ).

Although the CAF + AM group (test group 2) demonstrated clinical improvements comparable to the other two groups across all parameters, including PPD, CAL, RD, KTW, and GT, the differences did not reach statistical significance ( P > 0.05), suggesting a positive trend without conclusive evidence of superiority.

Short-term fasting (≤3 days; k = 15) showed a trend toward reduced triglyceride levels (g = −0.335; 95% CI: −0.684 to 0.013), although this effect did not reach statistical significance.

The expansion of activated memory B cells observed at M2 negatively correlated with CD4 T-cell frequency (p = 0.022), positively correlated with CD8 T-cell activation (HLA-DR+CD38+ cells, p = 0.033), and showed a positive trend with VL that did not reach statistical significance.

AS alone resulted in weight loss comparable to sham and TBI alone, whereas the combination of TBI + AS showed a numerical trend toward nearly doubled weight loss compared with single AS or TBI exposure; however, this difference did not reach statistical significance (Fig. 4 A).

As shown in Figures 6d and 6e , lysosomes from nfe2l2 -KO mice showed a trend toward reduced RNASE uptake in comparison with Nfe2l2 -WT littermates, although it did not reach statistical significance.

Serum OPN concentrations also showed a trend toward being lower in patients with decreased ALM/W index values, although this difference did not reach statistical significance ( p = 0.060). 4.

Although the association in the elevated glucose group (FPG≥5.6 mmol/L) did not reach statistical significance ( P = 0.072), possibly due to a relatively smaller sample size, the higher point estimate (OR=1.46) suggests a possible trend toward a stronger association.

In the unadjusted crude model, both the Pre-frail group (OR = 1.6, 95% CI: 1.0–2.6; P = 0.061) and the Frail group (OR = 1.7, 95% CI: 0.9–3.1; P = 0.088) showed a trend toward increased odds of infection compared to the Robust reference group, although these associations did not reach statistical significance.