Barely Significant
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did not reach statistical significance

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In the literature

did not reach statistical significancep = 0.0511.0× alphaplainly factual
MFC-MRD–free survival showed a favorable trend in the maintenance group, although this did not reach statistical significance (2-year MFC-MRD–free survival: 85.5% [95% CI, 74.4–98.3] vs. 68.7% [95% CI, 57.3–82.4], p = 0.051).
Of note, the blastocyst formation rate exhibited a decreasing trend with higher TyG quartiles; in Q4 compared with Q1, the adjusted difference was − 2.37% points (β = − 2.37; 95% CI, − 4.78 to 0.03), which did not reach statistical significance, and other quartile contrasts were likewise non-significant.
did not reach statistical significancep = 0.0661.3× alphaplainly factual
Correlation of PIK3CA mutations with outcome Patients enrolled in the G3 trial who had tumours with PIK3CA mutations showed a trend towards worse invasive disease-free survival (iDFS) compared to those with PIK3CA wild-type tumours, although this difference did not reach statistical significance (HR 2.1 (95%CI 0.95–4.78); p = 0.066) (Fig. 4 ).
did not reach statistical significancep = 0.05061.0× alphaplainly factual
UUO isotype control kidneys showed a trend toward increased ICAM-1 expression in PTC compared with platelet-depleted animals, consistent with Icam1 mRNA, although the difference did not reach statistical significance (median 2 vs. 1; p = 0.0506, Mann–Whitney test, Fig. 2 F).
In the unadjusted crude model, both the Pre-frail group (OR = 1.6, 95% CI: 1.0–2.6; P = 0.061) and the Frail group (OR = 1.7, 95% CI: 0.9–3.1; P = 0.088) showed a trend toward increased odds of infection compared to the Robust reference group, although these associations did not reach statistical significance.