“did not reach statistical significance”

While the GMV of the left thalamus in patients with dystonia (mean ± SD: 7092.346 ± 816.061) showed a trend towards reduction compared with that in healthy controls (mean ± SD: 7224.300 ± 927.542) ( P uncorrected = 0.011), it did not reach statistical significance after correction for multiple comparisons.

Although there was an overall trend for lower estimates as compared to the non-parametric methods, these differences overall did not reach statistical significance.

KCC2 heterozygous mice showed a trend toward a higher seizure severity compared to the wild type strain, but it did not reach statistical significance ( z = 0.14).

At 50 μM, azure A also showed a trend towards inhibition but it did not reach statistical significance.

Summarizing the BM AML cell engraftment relative to PBS-treated mice across the three PDX models showed a trend towards reduced AML levels was observed in the PBMC + DNT group compared to the PBMC + PBS group, although the difference did not reach statistical significance ( p = 0.0645) (Figure S3B), potentially due to the limited sample size, variability among patient samples, and the potent anti-leukemic activity mediated by PBMCs alone.

MIG level also showed an increasing trend but did not reach statistical significance (486 ± 1401 vs. 649 ± 1147 pg/mL, P = 0.069).

For the OS, a PR-positive status showed a trend toward reduced mortality risk compared with the PR-negative patients (HR, 0.61; 95% CI, 0.30–1.24), though this did not reach statistical significance ( p = 0.173).

The results showed that the proportion of S-phase cells exhibited an increasing trend but did not reach statistical significance, suggesting that the anti-ageing mechanism of cAMP did not depend on enhanced cell proliferation ( Fig. 3A ).

In the noninfarct area, however, the difference in apoptosis between antagomir and control group hearts only showed a trend towards reduction but did not reach statistical significance ( Figure 4(c) ). qPCR showed that miR-208a silencing in MI also decreased Bax levels at 28 days ( Figure 4(d) ).

While correlation between SubC and MRI brain volumetry did not reach statistical significance for this small sub-cohort, there was a weak trend of lower ICV and GM volumes at higher SubC values for CLN2 R208X/R208X miniswine at 17-months-of-age (Supplementary Fig. 1 ).

There was a clear trend between radiographically presumed and histopathologically verified tumor response, which did not reach statistical significance due to the small number of enrolled patients.

In CFA3D, PRE-084 showed a trend toward hyperpolarizing the threshold, although this effect did not reach statistical significance ( p = 0.09, Figure 6 C).

It should be noted, however, that serum levels of AST and ALT, both markers of hepatocellular injury, as well as urea, creatinine, and LDH, markers of kidney and systemic organ injury, showed a trend toward lower values in the DNase-treated mice, although this did not reach statistical significance (Table 1 ).

Interestingly, 5 out of 8 patients showed a trend of increasing in Dll4 expression but the difference did not reach statistical significance ( Fig 7C ).

A slight trend toward reduced rates of proliferation were observed in the HTN (+) HFpEF group but did not reach statistical significance.

BCR-activated B cells also showed a strong trend for increased MHCII expression after coculture with MCs, although this finding did not reach statistical significance ( Fig. 1h ).

On the other hand, binding of rEgAgB8/2 to macrophages was not observed; the binding index showed a trend to increase in a dose dependent manner, but this trend did not reach statistical significance (Fig. 4a ).

The capsular repair showed a trend toward increasing anteroinferior translational stability compared to the Latarjet procedure, but this did not reach statistical significance.

In WT mice injected with LpX ( Fig 5A ), a small trend toward increasing UACR values was observed but did not reach statistical significance ( P = 0.106, One Way ANOVA).

While continued anticoagulation showed a trend toward lower stroke risk, this difference did not reach statistical significance.

Comparing the diameter of unruptured to ruptured aneurysms, we found a slight trend that did not reach statistical significance towards a greater diameter in the unruptured group compared to the ruptured group.

Elevated hs-CRP levels showed a trend towards poorer cognition in individuals experiencing SCD, though this did not reach statistical significance ( Zhang et al., 2023 ).

Ang II treatment with losartan (A + L) showed a trend toward a higher colocalization ACE2 with LRP2 compared to Ang II alone but did not reach statistical significance.

The results of the ELISA did not reach statistical significance, perhaps because of fewer replications and high individual variation, but it showed a decreasing trend.

HAS 2 expression in the c-Met group showed an increasing trend, although it did not reach statistical significance.