There was a slight trend, but one that did not reach statistical significance, for increased total PDE4 activity in mice fed an HFD for 3 weeks vs. mice fed an ND (Supplementary Fig.
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In the literature
There was a slight trend for an increase in FVC after NIV-supported ACT, especially in the morning session, and although this did not reach statistical significance it may make NIV support a viable consideration in patients with loss of lung volume.
Although exploratory analysis showed a trend towards lower leptin levels after an incomplete course of steroids, this did not reach statistical significance, and it is unclear if the association could be related to an acute suppressive effect of the initial steroid dose on placental leptin transfer and/or a stimulatory effect of >24 hour steroid exposure on adipocyte leptin production.
a clear trendgold
The differences between SLE TLR7 hi and TLR7 norm/lo groups did not reach statistical significance (p-value = 0.06, by Fisher's exact test), but there was a clear trend toward G-risk genotype enrichment in the TLR7 hi group.
a marked trendgold
At high shear rate, there was a marked trend toward reduced thrombogenicity that did not reach statistical significance [19.6% reduction in median thrombus from 8788 (1325) μm 2 /mm to 7066 (2516) μm 2 /mm, P = 0.176] ( Fig. 3A ).
Quantification of fluorescence in the superior colliculus showed a trend toward a decrease in transport at 2 days post-blast that did not reach statistical significance ( Figure 4E ).
Although pharmacological inhibition of sEH showed a trend to limit mitochondrial expression of Mfn-2, it did not reach statistical significance compared to WT IR hearts ( Figure 6 B).
Evaluation of jerk forces at the shoulder in this study showed a trend toward high jerk forces with sliders compared to fastballs [ 46 ], but this did not reach statistical significance with our limited sample of pitchers.
The faces scale, a subset of the BRWP, showed a trend toward benefit but did not reach statistical significance (p=0.085).
IgG1 levels showed a trend towards an increase, but did not reach statistical significance (IgG1 P = .09).
This did not reach statistical significance (p=0.29, χ 2 1.117) but showed an important trend, given the rarity of moderate, severe or catastrophic adverse incidents.
Our findings indicate that the total number of steps per day and the amount of vigorous activity showed a positive trend toward patients in remission, although this did not reach statistical significance.
Despite a strong trend towards greater timing adherence with dry powder capsules, the difference between the two study groups did not reach statistical significance.
AZD8848 showed a trend towards decreased maximal LAR fall in FEV 1 versus placebo at 1 week after dosing, but this reduction did not reach statistical significance (18% decrease vs placebo; p = 0.076).
Levels of p21 Cip2 and tp53 were also examined and showed a trend toward reduction in the rapamycin-treated samples, but the changes did not reach statistical significance.
a strong trendgold
There was a strong trend for lower trabecular bone volume fraction in female vertebrae compared with male vertebrae, which, however, did not reach statistical significance ( p = 0.1).
A second study [ 12 ] compared Eribulin against capecitabine in 1102 patients and showed a trend towards better OS: 15.9 months in Eribulin versus 14.5 in control; however, this difference did not reach statistical significance ( p = 0.056).
However, the effect of miR-195-5p on CPNE1 expression did not reach statistical significance and it just showed a trend toward significance based on the Linkedomics public dataset (Figure 4 D).
In another occupational study, a positive trend based on exposure-response was observed for pancreatic and prostate cancer, although these did not reach statistical significance [ 35 ].
Effects of the resident workshop Residents’ teaching effectiveness and their impact on students’ rotation experience showed a trend of increase after the workshop, but this did not reach statistical significance ( p = 0.35).
Interestingly, when looking at the changes within individual clusters, decreases did not reach statistical significance although there was a clear trend ( Figure 3 H–J).
The odds of prospective trial registration showed a trend towards significance for industry funded trials, with a 2.5 times greater likelihood of trial being registered prospectively before enrolment; however, the trend did not reach statistical significance.
1e ), while the distal segment (−1550 bp to −1350 bp), segment 3, only showed a trend of reduction, but did not reach statistical significance (Fig. 1e ).
The trabecular separation displayed a decreasing trend in the CDH-13-treated group, but the difference did not reach statistical significance ( Figure 5J ).
A decreasing trend in serum SOD levels was noted with increasing severity of premature canities; however, it did not reach statistical significance [Tables 3 , 4 and Figures 1 , 2 ].