Barely Significant
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did not reach statistical significance

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In the literature

The pre-dementia group had fewer hospital visits related to pancreas cancer (IRR = 0.82, 95% CI: 0.69–0.98, FDR-adjusted P = 0.010), and showed a trend toward fewer visits for colon cancer (IRR = 0.95, 95% CI: 0.91–1.00, FDR-adjusted P = 0.056), though it did not reach statistical significance.
Additionally, the interaction between time × APOE ε4 status showed a trend toward significance ( F [1,90] = 3.736, p = 0.056, partial η 2 = 0.040), suggesting that the decline in distress over time may have been moderated by genetic risk, although this effect did not reach statistical significance. χ 2 Tests examined whether behavioral adaptations (yes/no) differed between the online and onsite intervention groups at 3 and 6 months.
Contrary to expectations, our study showed that the mediating effect of FT on the DII-S-Klotho association did not reach statistical significance, but displayed a trend towards significance after controlling for confounding factors (p = 0.056).
a negative trendp = 0.05651.1× alphagold
did not reach statistical significancep = 0.05651.1× alphaplainly factual
Although the association between total training sessions and DBP improvement showed a negative trend, it did not reach statistical significance (β = −0.0340, p = 0.0565), implying that increasing the number of sessions may contribute to DBP reduction, but the evidence remains insufficient.
There was a clear trend towards significance in the association between high SERPINE1 expression and poor patient survival (HR 1.78, 95%CI 0.98–3.23, p = 0.057), however the differences observed among groups, did not reach statistical significance in the multivariate analysis.
Finally, in the analysis of the total MFI score, as shown in Supplemental Figure S4a and b, blood samples showed a suggestive trend toward an association with homocysteine degradation (Holm p = 0.057, FDR = 0.032), although this did not reach statistical significance.
did not reach statistical significancep = 0.0571.1× alphaplainly factual
showed a trendp = 0.0571.1× alpha
Close margins showed a trend toward increased risk that did not reach statistical significance (hazard ratio 2.18, 95% CI 0.98–4.86, p = 0.057; 8 events among 38 patients), likely reflecting limited statistical power given the small number of events.