“did not reach statistical significance”

Finally, in the analysis of the total MFI score, as shown in Supplemental Figure S4a and b, blood samples showed a suggestive trend toward an association with homocysteine degradation (Holm p = 0.057, FDR = 0.032), although this did not reach statistical significance.

There was a clear trend towards significance in the association between high SERPINE1 expression and poor patient survival (HR 1.78, 95%CI 0.98–3.23, p = 0.057), however the differences observed among groups, did not reach statistical significance in the multivariate analysis.

While this model did not reach statistical significance; perspective taking was the only variable that approached significance, ß = 0.388, t = 1.99, p = 0.057.

Close margins showed a trend toward increased risk that did not reach statistical significance (hazard ratio 2.18, 95% CI 0.98–4.86, p = 0.057; 8 events among 38 patients), likely reflecting limited statistical power given the small number of events.

Although the levels of IL-1β did not reach statistical significance among treatment groups, mice treated with HC1, HC4, SBS1, SBS2, and SBS3 showed a trend of inhibition ( p = 0.057) compared to the mice that received PBS alone ( Figure S3D ).

We found Diet had a strong trend towards reducing the F/B ratio ( p = 0.0574) but it did not reach statistical significance (Figure 3c ).

Although the difference approached significance, it did not reach statistical significance ( p = 0.058).

Although the mediation effects for SDoH = 1 and SDoH = 2 did not reach statistical significance, it was noteworthy that the effect for SDoH = 2 approached significance for both mortality outcomes ( P = 0.058).

In contrast, beta-blockers showed a trend toward a protective effect (OR: 0.47, 95% CI: 0.22–1.03, P = 0.058), though this did not reach statistical significance.

This showed a strong trend in the logistic regression model ( p = 0.058) which did not reach statistical significance possibly due to the small sample size (Type I statistical error).

Women with normal weight (18.5 ≤ BMI < 24.0 kg/m 2 ) also showed a trend toward reduced risk (OR = 0.73, 95% CI: 0.53–1.01, p = 0.058), although this did not reach statistical significance.

Although tumor invasion of the ventricle showed a strong trend, it did not reach statistical significance in the multivariate model (OR = 6.21, 95% CI: 0.94-41.15, P = 0.058).

A notable trend was observed between the groups after the 12-week intervention period when comparing the change in area under the curve (ΔAUC) for glucose ( p = 0.058); however, this result did not reach statistical significance.

Although unmarried patients showed a trend toward worse DSS, this finding did not reach statistical significance (HR = 1.285, p = 0.058).

In this study, patients who received radiotherapy during systemic treatment showed a trend toward improved iPFS compared with those who underwent radiotherapy prior to starting this regimen (P = 0.058), although this did not reach statistical significance due to the retrospective design and limited sample size( supplement Figure2 ).

DAT−/− rats showed a 1.5-fold increase in the levels of ALDH1L1 (one-way ANOVA F (2, 14) = 11.79; p = 0.0010; Tukey’s multiple comparison test p = 0.0007 DAT−/− versus DAT+/+ controls), while DAT+/− rats showed a trend toward elevation that did not reach statistical significance (Tukey’s multiple comparison test p = 0.0586 DAT+/− versus DAT+/+ controls; Figure 4 A).

Although post hoc comparisons did not reach statistical significance after Bonferroni correction, a clear trend toward higher TAN counts was observed in the c-erbB2-positive group compared with the c-erbB2-negative group (mean rank = 36.65 vs. 28.91, p = 0.059) ( Table 4 , Chart 4 ).

Glycaemia at daytime versus night‐time during the 5‐day exercise period While there was a numerical trend for more time spent in euglycaemia for the 75% IDeg dosing period during night‐time, it did not reach statistical significance ( P = 0.059; Table 3 ): 3.5.

A favorable trend was also observed for overall survival (OS) (HR = 0.75, 95% CI: 0.55-1.01, P = 0.059, Figure 3F ), although this did not reach statistical significance.

Carer psychological distress showed a positive trend in its association with increasing PLWD unmanaged symptoms (coefficient = 0.07, 95% CI [−0.00, 0.13], p = 0.059) and agitation (coefficient = 0.06, 95% CI [−0.01, 0.14], p = 0.090), but both analyses did not reach statistical significance.

RFDR showed a tendency toward significance (F = 2.893, p = 0.059, η 2 = 0.048) but did not reach statistical significance after adjustment.

The root extracts showed a trend toward increasing CASP9 expression ( p = 0.059), but this did not reach statistical significance, meaning that while there might be a potential effect, the data do not provide strong enough evidence to confirm a reliable upregulation at the tested doses.

However, the difference in AST and ALP did not reach statistical significance ( p = 0.378 for AST, p = 0.190 for ALP), while GGT showed borderline significance ( p = 0.059). 3.4 WQS regression The eight components that make up the LE8 score were evaluated for their impact on these liver function parameters ( Figures 3A – E ).

While a positive trend was observed between GRS and fasting C-peptide (β = 0.0228), this association also did not reach statistical significance (p = 0.059).

The differences seemed fairly small and did not reach statistical significance, excepting a marginally significant difference in the estimated relations of social and emotional intelligences with visuospatial processing ( r = 0.29 versus r = 0.17, respectively, p = 0.06).