Barely Significant
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did not reach statistical significance

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In the literature

did not reach statistical significancep = 0.12.0× alphaplainly factual
showed a trendp = 0.12.0× alpha
For hostility, although both HIFT and MICT groups showed a trend toward improvement, the changes did not reach statistical significance (main effect of time: p = 0.1).
Limbs with any non-closure also showed a trend toward less symptom improvement (“much better:” 50.0% vs 79.6%; P = .10) and less improvement in visual appearance (“much better:” 66.7% vs 81.6%; P = .083), although these differences did not reach statistical significance.
did not reach statistical significanceP = 0.1002.0× alphaplainly factual
showed a trendP = 0.1002.0× alpha
Furthermore, trend analysis ( Table 3 ) confirmed a significant stepwise increase in mortality risk as LDL-C quartiles decreased ( P for trend = 0.024). In the survival analysis, although the KM curves for the four quartile-based groups showed a trend of separation, the difference did not reach statistical significance ( Figure 1C , P = 0.100).
A pooled analysis of 8 randomized clinical trials involving 2281 patients with STS demonstrated a slight trend favoring doxorubicin-based combination therapy for ORR (odds ratio [OR], 0.79; 95% confidence interval [95% CI], 0.60-1.05 [ P = .10]); these results, as well as OS data (OR, 0.84; 95% CI, 0.67-1.06 [ P = .13]), did not reach statistical significance compared with single-agent doxorubicin. 16 Nausea, vomiting, and myelosuppression were consistently more severe with the combination regimens.
did not reach statistical significancep = 0.1022.0× alphaplainly factual
showed a trendp = 0.1022.0× alpha
Additionally, all patients in both groups who had subcardiac spurters had fully healed (100%); Although the differences did not reach statistical significance, the urgent endoscopy group showed a trend toward more complete eradication of gastric varices ( p = 0.102) and a higher incidence of cyanoacrylate-induced ulcers ( p = 0.138), the later could be explained by issues not related to urgent endoscopy itself rather than other patient’s co-morbid condition ( Table 3 ).
However, in multivariable Cox regression models adjusted for TNM stage and history of breast disease, the GATA6high/TGFB2-AS1low signature did not reach statistical significance as an independent prognostic factor—though it showed a trend toward worse DFS (HR = 1.86, 95% CI: 0.88–3.93; P = 0.104) and no significant association with OS (HR = 1.15, 95% CI: 0.39–3.37; P = 0.799).