In the univariate model, PRMT7 high showed a trend to increased hazard for an event (HR = 1.81, 95% CI, 0.89–3.71, p = 0.1), but it did not reach statistical significance.
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Other miRNAs, such as miR-32-5p, miR-106a-5p, and miR-148b-3p, showed a trend toward upregulation ( p < 0.1), suggesting possible HPV-related modulation that did not reach statistical significance.
showed a trendp = 0.10
While high risk of hospitalization showed a trend towards increased mortality (log[OR] = 0.46), it did not reach statistical significance ( p = 0.10).
showed a trendp = 0.10
Although anti-dsDNA levels ≥100 IU/mL showed a trend toward association (OR = 2.66, 95% CI: 0.81–8.71), this did not reach statistical significance ( p = 0.10).
showed a trendp = 0.1
For hostility, although both HIFT and MICT groups showed a trend toward improvement, the changes did not reach statistical significance (main effect of time: p = 0.1).
Limbs with any non-closure also showed a trend toward less symptom improvement (“much better:” 50.0% vs 79.6%; P = .10) and less improvement in visual appearance (“much better:” 66.7% vs 81.6%; P = .083), although these differences did not reach statistical significance.
showed a trendP = 0.100
Furthermore, trend analysis ( Table 3 ) confirmed a significant stepwise increase in mortality risk as LDL-C quartiles decreased ( P for trend = 0.024). In the survival analysis, although the KM curves for the four quartile-based groups showed a trend of separation, the difference did not reach statistical significance ( Figure 1C , P = 0.100).
trending toward significanceP = 0.10
Although trending toward significance, the variance between the groups did not reach statistical significance ( P = 0.10).
A pooled analysis of 8 randomized clinical trials involving 2281 patients with STS demonstrated a slight trend favoring doxorubicin-based combination therapy for ORR (odds ratio [OR], 0.79; 95% confidence interval [95% CI], 0.60-1.05 [ P = .10]); these results, as well as OS data (OR, 0.84; 95% CI, 0.67-1.06 [ P = .13]), did not reach statistical significance compared with single-agent doxorubicin. 16 Nausea, vomiting, and myelosuppression were consistently more severe with the combination regimens.
Diet quality showed a positive trend (Adjusted OR 1.16, 95% CI 0.98 to 1.37, p = 0.100) but did not reach statistical significance in the fully adjusted model.
Even if these reductions did not reach statistical significance, a decreasing trend could be observed in EGR1, IL‐6 and IL‐1β ( #, p ≤ 0.1).
[ 10 ] found only a weak trend toward prologation of QTc duration with methadone dose, which did not reach statistical significance (r = 0.13, P = 0.1).
showed a trendp = 0.1
While the Luminal B poor-prognostic gene set showed a trend toward worse outcomes (HR = 1.663, 95% CI: 0.9–3.074), this association did not reach statistical significance (Log-rank p = 0.1; Figure 6 D).
Although several correlations did not reach statistical significance, some variables demonstrated a trend toward significance (0.05 < p < 0.1).
Although LI11 demonstrated an increasing trend relative to sham, this difference did not reach statistical significance ( p = 0.10).
In the age group 40–59 years, this negative correlation approached significance ( β coefficient = −0.009, p = 0.1004) but did not reach statistical significance.
showed a trendp = 0.101
non-postCTx group) showed a trend towards prolonged survival in the non-postCTx groups, which did not reach statistical significance ( p = 0.101).
showed a trendp = 0.102
Additionally, all patients in both groups who had subcardiac spurters had fully healed (100%); Although the differences did not reach statistical significance, the urgent endoscopy group showed a trend toward more complete eradication of gastric varices ( p = 0.102) and a higher incidence of cyanoacrylate-induced ulcers ( p = 0.138), the later could be explained by issues not related to urgent endoscopy itself rather than other patient’s co-morbid condition ( Table 3 ).
showed a trendp = 0.102
While pNmi showed a trend toward worse survival, it did not reach statistical significance in either DFS (HR 2.351, 95% CI: 0.843–6.557, p = 0.102) or DSS (HR 2.572, 95% CI: 0.657–10.066, p = 0.175).
Laterality showed a trend towards higher risk for hypothyroidism with left-sided surgery (adjusted HR 1.682, 95% CI [0.903, 3.134], p = 0.102), but this did not reach statistical significance in the multivariable model.
Initial visual acuity of ≥ 20/200 showed a trend toward better outcomes (OR = 2.35; 95% CI [−0.48–5.18]; p = 0.102), though it did not reach statistical significance ( Table 2 ).
Autoimmune Mechanism In our study, a history of autoimmune disease showed a trend toward an increased risk of recurrence (HR = 2.99, p = 0.104), although this did not reach statistical significance.
However, in multivariable Cox regression models adjusted for TNM stage and history of breast disease, the GATA6high/TGFB2-AS1low signature did not reach statistical significance as an independent prognostic factor—though it showed a trend toward worse DFS (HR = 1.86, 95% CI: 0.88–3.93; P = 0.104) and no significant association with OS (HR = 1.15, 95% CI: 0.39–3.37; P = 0.799).
Although, the difference between low and high expression groups did not reach statistical significance, there was a strong trend towards a difference (P=0.1055).
In contrast, while ANXA3 expression showed a positive trend, its correlation did not reach statistical significance ( r = 0.12, p = 0.106).