“highly significant”

A highly significant correlation (half-life: Spearman's r = 0.67, P ≤ 1e -16 ; decay rate: r = 0.64, P ≤ 1e -16 ) was obtained, supporting the initial finding that RNA stability becomes more pronounced with increasing distance from the promoter.

The perfect association of the haplotype was highly significant (p<10 −16 ).

Figure 3 illustrates the interactome for DS3, featuring 257 edges, 57 nodes, an average node degree of 9.02, and a highly significant PPI enrichment p -value of <1.0 × 10 −16 .

The trend is weaker in lincRNAs compared with protein-coding genes (rho = 0.2 and 0.28, respectively) but both correlations are highly significant (from Spearman: P < 10 − 16 ).

The interaction between fingertip ROI and stimulation condition was highly significant ( F 16,80 = 71.7, P < 10 −16 , Greenhouse‐Geisser correction: F 1,5 = 71.7, P < 10 −3 ).

This difference between MS patients and non-MS controls is highly significant ( p < 10 − 16 ) .

Initial mapping using an imputed genotype matrix for 2029 accessions (Togninalli et al ., 2018 ) revealed a highly significant peak associated with symptom score and total SA levels (−log 10 ( P ) = 15.96 and 10.64, respectively) spanning over 10 Kb on Chromosome 2 (Figs 1 , S2 for SA) and one marker reaching significance on Chromosome 3 (−log 10 ( P ) = 7.59) that is only associated with symptom score.

AgeAccelGrim remains a highly significant predictor of lifespan after restricting the analysis to never-smokers (N=3,988, meta analysis P=1.1E-16, Supplementary Fig. 9 ) or to former/current smokers (P=3.5E-33, Supplementary Fig. 3A ).

The M3 from the Japanese cohort wholly covered all the genes involved M11 from the TCGA cohort, which is highly significant overlap (n=41, hypergeometric test, P < 1.1e-16, Figure 2 g).

Irrespective of clades, all strains treated with 4 wt%Ag/TiZSM-5 zeolite and Ag-silicalite-1-nanomaterial showed highly significant inhibition for both biofilm [(24 h; F = 57.4079 and p = 1.1102 × 10 −16 ) (48 h; F = 43.3833 and p = 1.1 × 10 −16 ) and planktonic C. auris, compared to the control conditions.

It was found that the level of significance was highly significant ( P = 1.1102e-16).

The enrichment of SRCAP variants in the Caribbean Hispanic patients with LOAD was highly significant at p = 1.19e-16.

As shown in Table 1 , the pMHCs that induced higher contact areas also induced more rapid initial spreading, although the initial spreading rate displayed only 1.8-fold variation depending on stimulation peptide, but peptide discrimination remained highly significant ( p = 1.3 × 10 −16 ).

During the active period with lights off there was a highly significant difference between males and females (p = 1.3E-16) and also some difference between sites (p = 1.1E-3) with a significant interaction between site and sex (p = 3E-6) ( Fig 6a and 6b ).

This up-regulation was highly significant on meta-analysis (Fisher’s combined P = 1.4 × 10 −16 , Fig. 2C ).

Highly significant increases in median nFLAIR, CNI, and CCrI were observed for NAV→NEL ( p = 1.5 × 10 –16 , 2.4 × 10 –15 , 2.8 × 10 –16 , respectively) voxels compared to stable NAV voxels, while increases in median nADC also reached a statistical significance of p = 0.0009.

In the univariate model, PIP (chosen to represent all other heart rate fragmentation measures) demonstrated a highly significant ability to predict mortality (p = 1.71E-16).

After including non-LA ω-6 PUFA in the model, the association of the FADS with LDL-c remains highly significant ( p < 2.0 × 10 −16 ).

For males both age and puberty score were highly significant in predicting height at age 11 (r 2 = .17, p<2e −16 ) and 14 (r 2 = .23, p<2e −16 ).

Although, the correlation was highly significant ( p < 2e-16), the R2 of only 0.57 shows a low predictive power.

This difference in wing length was highly significant (t = −57.479, p < 2e-16).

Evolutionary niche shift in response to the mean salinity The mean salinity experienced during evolution had a highly significant effect on acclimated tolerance surfaces ( P < 2 × 10 –16 , likelihood‐ratio test—hereafter LRT—between models with vs. without effects of salinity mean).

In particular, in 10-fold cross-validation experiments on held-out genes, we obtained a mean Spearman rank correlation between predicted and measured gene expression changes of 0.174, a modest but highly significant result ( P <2e−16), shown in Figure 2A .

Laminar quantification showed a highly significant difference in Iba1 intensity across cortical layers [ F (4,531) = 90.19, p < 2 × 10 –16 ; one-way ANOVA] with the highest intensity in L1 ( Figure 7E ; L1 vs.

The difference in this distribution was highly significant ( χ 2 p-value<2e-16).