In summary, considering HCN NOS, HB FPAs, and older patients with HB, we found near-significant and significant associations between outcomes and metastatic disease or transplantation at p = 0.02 and p = 6E-4 by FET, respectively.
These findings were replicated when the analysis was adjusted for BSA with the addition of the mid-RCA segment, which was borderline near-significant (p value 0.051) ( table 4 ).
The near-significant associations of these functionally relevant genes suggest that they may contribute to OCD pathophysiology through disrupted ion channel function and neuronal excitability.
The near-significant between-strain difference under high-illumination conditions further implies that genetic predisposition to hypertension influences autonomic responses to environmental stimuli, with SHRs consistently exhibiting higher sympathetic predominance than do their normotensive counterparts.
O 3 was the only air pollutant that showed significant and near-significant associations with health outcomes among older adults (ages 65+).
DV0 and SV90 Z score were calculated separately using the formulas: 1 2 Significant or near-significant associations identified in the correlation matrix (particularly FARS and GAA1) were further examined using linear regression models (to allow simultaneous consideration of variables of age and GAA1, which are linked in based on disease severity).
Where there were significant or near-significant interactions with gender, we calculated actor and partner effects separately for males and females using dummy codes for each gender in a two-intercept model (see Kenny, Kashy, & Cook, 2006 ).
Follow-up comparisons within the left IFG cluster showed a near-significant priming effect in the higher predictive validity blocks (Z = 2.67, p FWE = 0.054).
In summary, univariate analysis highlights widowed marital status, certain blood groups, obesity, pregnancy, elevated body temperature, and RBS as significant or near-significant predictors of mortality among COVID-19 patients.
In the original research, using cohort 1, no such near-significant value was found [ 14 ].
There was a near-significant interaction in Word reading between pre-post training and all the trained groups (except the CG), suggesting a possible generalized enhancement.
A near-significant correlation was observed between advanced-stage cancer and increased fatigue levels.
[ 18 ] reported a near-significant 5.3% improvement in cycling time-trial performance (effect size of 0.58) compared with placebo following 4 wk of consuming 75 g/d of almonds.
We likewise found a phylogenetic signal in bacterial ASV richness, Bd-inhibitory bacterial richness, and Bd load and a near-significant effect in Bd prevalence, all of which remained significant when we accounted for intraspecific variation ( Table S7 ).
Therefore, we described it as a ‘near-significant’ observation, emphasizing that confirmation requires larger, prospective studies with greater statistical power.
The near-significant difference between the male and female gender frequency might be related to the transmission route – higher number of women was infected sexually.
Genes displaying this trend with significant increases in all comparisons ( p < 0.05, Wilcoxon rank-sum test) or near-significant increases included known key immune/interferon response genes ( AIM2 , CLEC5A , CTSD, FCGR1A , FCGR1B , IFI16 , PSMB8 , SP100 ), stress/chemical response-associated heat-shock chaperonin protein HSPD1 , Krüppel-like factor transcriptional regulator KLF4 , and mitochondrion-associated genes CISD1 (CDGSH iron sulfur domain redox-active protein) and MTHFD2 (methylenetetrahydrofolate dehydrogenase).
Except for the affected-to-unaffected hand temperature difference, both groups consistently demonstrated significant or near-significant improvements in measured parameters after MT period.
The lesion site was near-significant at unadjusted P value of 0.05, thus requiring further examination.
Although the analysis considered all age groups, only the ≥46 years category displayed a statistically significant (or near-significant) association with the outcome in the final adjusted model.
For SNPs with significant allele and interaction coefficients, a meaningful allele main effect was considered present if the single-condition vehicle and ATRA analyses showed the same allelic direction of effect, with a vehicle Pemp < 0.1 and ATRA FDR < 0.1 (i.e., near-significant within each condition of n = 6, thus reasonably capable of achieving significance in the LMM analysis of the two conditions combined).
Despite the small sample size and the short supplementation time, significant and near-significant changes in several POMS scale were noted [ 86 ].
Although the majority of kittens in the study (regardless of treatment, age or disease severity at study entry) achieved the defined resolution or recovery endpoints, kittens receiving famciclovir along with antibiotics had a number of statistically significant or near-significant outcomes superior to those seen in kittens receiving antibiotics only.
They did not report the main effect of mimicry, but report a near-significant positive effect of mimicry on how non-anxious women evaluated the avatar in terms of likeability and friendliness.
In boys, participation in social activities was significantly positively associated with z-scores of BMI and WC and near-significant with z-scores of WHR in adulthood (Additional file 1 : Table S4 and Table S5).