“nominally significant”

There is a nominally significant rs11854251‐ LINC00923 association in the spinal cord (cervical c‐1) ( p = 0.032).

11 We only found a nominally significant association of rs10191329 with the yearly change rate of the lateral ventricles ( p = 0.032), but not with any of the other 14 investigated metrics, including yearly change rates of the total brain volume ( p = 0.690), thalamus ( p = 0.953), or putamen ( p = 0.613).

38.9%), with a nominally significant difference in the remission rate (p = 0.032) but not in the response rate (p = 0.28).

The association with previous VTE for one SD increase in CFHR5 level in VEBIOS Coagulation was still nominally significant when adjusting for C3 levels (OR 1.36 [CI 1.03-1.82], p = 0.032), although weaker compared to adjusting only for age and sex (OR 1.55 [CI 1.2-2.01], p = 8.85E-04, Table 3 and Supplementary data 1 [Tab_8] ).

Supplementary data thorax-2023-220856supp002.xlsx Causal estimate for seropositive RA on IPF The primary IVW-FE analysis gave a nominally significant result for a protective causal effect of seropositive RA on IPF (OR 0.93; 95% CI 0.87 to 0.99; p=0.032) ( figure 2A and online supplemental table 6A ).

GlycanAge was significantly lower in the active group compared to the inactive group (β = -7.437, p.adj = 7.85E-03), and nominally significant and increased in professional athletes compared to the active group (β = 7.546, p = 3.20E-02).

Interestingly, one suggestive signal for tau‐PET on Chr7 ( CRYGN,RHEB /rs12538040, MAF = 0.196, P = 3.80E‐07, β = −0.84) was also nominally significant with the same direction for p‐tau217 ( P = 0.032, β = −0.21). 3.4 Mult‐trait GWAS Multi‐trait GWAS was performed on a subset of 76 participants from ABC‐DS with all four tau biomarker measurements available, aiming to identify pleiotropic loci that simultaneously contribute to all tau biomarkers.

Analysis of the allelic distribution among patients according to their asthma severity also indicated nominally significant associations of allele A of IL-4Rα A1199>C, allele T of IL-4Rα T1570>C and allele A of TNFα TNFα C-863>A with asthma severity (p = 0.033, p = 0.018 and p = 0.047, respectively).

The results showed the same trend for increased right-hand skill in carriers of the minor allele; the association was nominally significant with rs11855415 ( P = 0.033, β = 0.19, Table 1 ), but did not meet significance for rs9806256.

In contrast, cognitive function demonstrated a nominally significant moderating effect ( p = 0.033, adjusted R2= 33.09%; Fig. 3 D).

Pre-gestational DM showed a nominally significant inverse association (OR 0.32; 95% CI 0.11–0.91; p = 0.033); however, this result should be interpreted with caution given the very small number of pre-gestational DM cases ( n = 22 total).

Comparing MDD-SI and MDD-nSI, nominally significant group × time interactions were observed for the λ ( F = 4.530, p = 0.033; β = 0.725, 95% CI: 0.049 to 1.400), and nodal efficiency exhibited a nominally significant group × time interaction in the right posterior cingulate gyrus ( F = 3.958, p = 0.046; β = -0.783, 95% CI: -1.565 to -0.003).

Moreover, we found nominally significant effects (uncorrected) of PAE for FA in the ICP-R (p = 0.033) and SS-L (p = 0.021).

C3 showed a nominally significant risk association under the weighted median model (OR = 1.651, P = .034).

From pre- to post-intervention ( Table 2 ), a nominally significant improvement in IL-6 was observed across all participants ( p = 0.034, effect size = 0.879, 95% CI = 0.879–0.879).

The sole exception was Bacillus subtilis strain 3610, for which the interaction between time post-infection and maternal condition was weakly nominally significant ( S2 Table ; p = 0.034).

Nominally significant association was found between SPON1 and Ecc_global ( P = 0.034).

Results A nominally significant association was found between the G-allele of 941G/T in MAO-A and ADHD (TDT: P = 0.034.

A nominally significant (p=0.034) improvement was observed in global alpha AEC-c.

SLE status was significantly associated with reduced XCI-skew in 40–49 years (p=9.4×10 −4 ) and 50–59 years (p=9.8×10 −4 ), after Bonferroni correction (alpha=0.0125), and nominally significant in the over 60 years group (p=0.034; online supplemental figure S1 ).

This specific observation reached a nominally significant association (r=-0.19; p=0.034; table 3 ).

In this study, although a nominally significant difference was observed in COVES between groups in the univariate analysis ( p = 0.034), this finding was not robust after false discovery rate correction (FDR-corrected, p = 0.129), indicating that the observed association may be marginal and should be interpreted with caution.

Hydration interactions on the cheeks were nominally significant before multiplicity (right cheek β interaction = 3.58, p = 0.034, q = 0.103; left cheek β _interaction = 2.81, p = 0.017, q = 0.077) but did not meet the FDR threshold, which, given the modest sample and group imbalance (38 vs. 15), raises the possibility of both Type I (false positives) and Type II (false negatives).

The set of 37 monogenic obesity genes showed a weaker but also nominally significant enrichment (2.05-fold enrichment, P = 0.034).

Specifically, adolescent MDD patients in the replication cohort exhibited nominally significant reductions in λ ( t = −2.14, P = 0.0342), L p ( t = −2.35, P = 0.0203), and E local ( t = −2.01, P = 0.0467).